Over-the-counter medicine
Aspirin First approved as Measurin
Aspirin (Measurin) is an over-the-counter medicine with an FDA approval on record since 1965. No generic is listed; pharmacies paid $0.0142 per aspirin ec 81 mg tablet in the October 7, 2026 NADAC survey.
- No generic listed
- A presentation discontinued
- Over the counter
Check it at the source: the aspirin FDA label on DailyMed (effective September 9, 2025); the NDA 16030 record on Drugs@FDA; every aspirin label on DailyMed.
Highlights of the record
FDA label of September 9, 2025; NDC Directory, Drugs@FDA and Orange Book, October 8, 2026; NADAC October 7, 2026
Used for
From the label: indications and usageTemporarily relieves headache toothache pain and fever of colds muscle pain menstrual pain minor pain of arthritis
Forms and strengths
- 81 mg
- 325 mg
- 500 mg
- 81 mg/811
- 325 mg/3251
- 500 mg/5001
Delayed-release tablet; chewable tablet; coated tablet; tablet; film-coated tablet.
On the market
- Earliest approval on file
- June 25, 1965 Measurin, Bayer; Drugs@FDA’s file, where older or withdrawn approvals can be missing
- Generic approvals
- No generic approved
- Labelers listed (NDC)
- 168 of which 0 under generic applications, 0 under brand applications, repackagers included
- Last listed patent
- September 29, 2032 Vazalore capsules; not a generic launch date
Supply and safety
- Pharmacy cost (NADAC)
- $0.0142 per tablet Aspirin ec 81 mg tablet
- Shortage (FDA)
- None current 1 past records
- Recalls by its makers (FDA)
- 1 since 2013 0 Class I among all firms' recalls; latest February 23, 2017; 5 more by firms not listed as its makers
- FAERS reports
- 534,208 through July 30, 2026
What is aspirin used for?
From the label: indications and usageTemporarily relieves headache toothache pain and fever of colds muscle pain menstrual pain minor pain of arthritis
Conditions named in the indications of aspirin's FDA labels, with every medicine labeled for each:
From other aspirin labelsPain, Cough and cold and Fever: Uses Temporarily relieves headache toothache pain and fever of colds muscle pain menstrual pain minor pain of arthritis
Source: FDA drug label (Medique Products Aspirin), Unifirst First Aid Corporation, effective September 9, 2025 (SPL set 9b28fed0-a993-ca72-e053-2995a90ac7fd), via openFDA; the full label on DailyMed
Is there a generic for aspirin (Measurin)?
No generic aspirin is approved (Drugs@FDA, October 8, 2026).
The Orange Book lists 4 patents for Vazalore capsules, the last expiring on September 29, 2032. A patent or exclusivity date is not the date a generic goes on sale: court cases and settlements move it either way.
- 1965 earliest approval on file
- 2032 last listed patent
- red ticks recalls
Source: Drugs@FDA, FDA NDC Directory and the Orange Book (openFDA bulk files, October 8, 2026)
What do pharmacies pay for aspirin (Measurin)?
In CMS's NADAC survey of October 7, 2026, pharmacies paid $0.0142 per Aspirin ec 81 mg tablet, down 2% from $0.0144 on October 8, 2025. The chart's scale runs from the lowest to the highest price shown, not from zero. NADAC is what retail pharmacies paid their wholesalers, per unit, in CMS's monthly survey; what a patient pays depends on insurance and the pharmacy.
- Aspirin ec 81 mg tablet (generic)
| Strength and form | Brand or generic | Pharmacy cost | 30 tablets, or one pen or vial | 12-month change |
|---|---|---|---|---|
| Aspirin 325 mg tablet | Generic | $0.0166 per tablet | $0.498 | +8% |
| Aspirin 81 mg chewable tablet | Generic | $0.0257 per tablet | $0.771 | -1% |
| Aspirin ec 325 mg tablet | Generic | $0.0222 per tablet | $0.665 | +4% |
| Aspirin ec 81 mg tablet | Generic | $0.0142 per tablet | $0.425 | -2% |
| Aspirin regimen 81 mg ec tablet | Generic | $0.0142 per tablet | $0.425 | -2% |
| Buffered aspirin 325 mg tablet | Generic | $0.0207 per tablet | $0.620 | +2% |
| Ft aspirin 325 mg tablet | Generic | $0.0166 per tablet | $0.498 | +8% |
| Ft aspirin 81 mg chewable tablet | Generic | $0.0257 per tablet | $0.771 | -1% |
| Ft aspirin ec 325 mg tablet | Generic | $0.0222 per tablet | $0.665 | +4% |
| Ft aspirin ec 81 mg tablet | Generic | $0.0142 per tablet | $0.425 | -2% |
| Gnp aspirin 325 mg tablet | Generic | $0.0166 per tablet | $0.498 | +8% |
| Gnp aspirin ec 81 mg tablet | Generic | $0.0142 per tablet | $0.425 | -2% |
| Gs aspirin 81 mg chewable tablet | Generic | $0.0257 per tablet | $0.771 | -1% |
| Qc aspirin 325 mg tablet | Generic | $0.0166 per tablet | $0.498 | +8% |
Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price
Is aspirin in shortage?
No aspirin presentation is listed as in shortage in the FDA Drug Shortage Database (read October 8, 2026); its 1 record is all marked to be discontinued, the latest updated July 23, 2026. ASHP keeps a separate shortage list, which can differ.
| Presentation | Company | Status | Updated |
|---|---|---|---|
| Aspirin, Suppository, 300 mg (NDC 0574-7034-12) | Padagis US LLC | To Be Discontinued | July 23, 2026 |
Source: FDA Drug Shortage Database via openFDA, updated October 8, 2026
Has aspirin been recalled?
The FDA's Enforcement Report lists 6 recalls naming aspirin since 2013: 0 Class I (the most serious), 6 Class II, 0 Class III; 1 still ongoing. 5 of them are by firms that FDA's NDC Directory does not list as a maker of aspirin and that hold no application for it in Drugs@FDA, such as compounding pharmacies or bulk-ingredient suppliers; the recall notice names the product recalled. A recall names products and lots, not every product of the medicine.
| Started | Class | Company | Reason |
|---|---|---|---|
| November 11, 2024 | Class II | Safecor Health, LLC not a listed maker | cGMP Deviations: Observations were made that some blister card-foils were separating from the blister cavity. |
| January 26, 2022 | Class II | CARDINAL HEALTHCARE not a listed maker | CGMP Deviations: Products were exposed to temperatures outside of the products labeled storage conditions. |
| February 23, 2017 | Class II | Mckesson Packaging Services | Presence of Foreign Substance: foreign material found in the bulk inventory. |
| July 2, 2013 | Class II | Aidapak Services, LLC not a listed maker | Labeling: Label Mixup; ASPIRIN Tablet, 325 mg may be potentially mislabeled as CHOLECALCIFEROL, Tablet, 400 units, NDC 00904582360, Pedigree: W002642, EXP … |
| July 2, 2013 | Class II | Aidapak Services, LLC not a listed maker | Labeling: Label Mixup: ASPIRIN, CHEW Tablet, 81 mg may have potentially been mislabeled as one of the following drugs: OMEGA-3 FATTY ACID, Capsule, 1000 mg … |
| July 2, 2013 | Class II | Aidapak Services, LLC not a listed maker | Labeling: Label Mixup: ASPIRIN, Tablet, 325 mg may have potentially been mislabeled as one of the following drugs: PANCRELIPASE DR, Capsule, 0 mg, NDC … |
Source: FDA Enforcement Report (drug recalls) via openFDA, through October 8, 2026
What does the aspirin label say about other medicines?
The aspirin label names no other medicine on this site. The labels of 29 other medicines name aspirin. The sentences are the labels' own; a label lists what its studies and reports found, not every interaction.
Other labels that name aspirin
- Abrocitinib
- Acellular tissue engineered vessel
- Acetaminophen and caffeine and dihydrocodeine
- Acetazolamide
- Alendronate
- Alteplase
- Anagrelide
- Apixaban
- Bismuth subsalicylate
- Celecoxib
- Citalopram
- Collagenase clostridium histolyticum
- Desvenlafaxine
- Dexamethasone
- Dichlorphenamide
- Diclofenac
- Diflunisal
- Dimethyl fumarate
- Diroximel fumarate
- Divalproex
- Duloxetine
- Eptifibatide
- Escitalopram
- Etodolac
- Fenoprofen
- Fludrocortisone
- Fluoxetine
- Fluvoxamine
- Hydrocortisone
- Ibandronate
- Ibuprofen
- Icosapent
- Indomethacin
- Ketoprofen
- Ketorolac
- Levomilnacipran
- Meclofenamate
- Mefenamic acid
- Meloxicam
- Melphalan
- Menthol and methyl salicylate
- Methazolamide
- Methotrexate
- Methylprednisolone
- Milnacipran
- Monomethyl fumarate
- Montelukast
- Nabumetone
- Naproxen
- Niacin
- Nitroglycerin
- Nizatidine
- Oxaprozin
- Paroxetine
- Piroxicam
- Prasugrel
- Prednisolone
- Ranibizumab
- Revakinagene taroretcel-lwey
- Rimantadine
- Rivaroxaban
- Sertraline
- Sulindac
- Tadalafil
- Tenecteplase
- Tolmetin
- Trazodone
- Triamcinolone
- Valproic acid
- Vardenafil
- Venlafaxine
- Verapamil
- Vilazodone
- Vortioxetine
- Warfarin
- Zafirlukast
Source: FDA drug label (Medique Products Aspirin), Unifirst First Aid Corporation, effective September 9, 2025 (SPL set 9b28fed0-a993-ca72-e053-2995a90ac7fd), via openFDA; the full label on DailyMed
What do FAERS reports show for aspirin?
The FDA Adverse Event Reporting System holds 534,208 reports that list aspirin among the medicines taken, through July 30, 2026, each a report of something that happened, not proof the medicine caused it; 48,992 are coded as a death and 208,873 as a hospital stay. Counts follow how widely a medicine is used and watched, and they are not a measure of how risky it is.
Reports received each year
The most reported reactions
Source: FDA Adverse Event Reporting System (FAERS) via openFDA, reports through July 30, 2026
What else is labeled for the same conditions as aspirin?
38 other medicines are given the same way (oral) and in the same FDA class as aspirin or labeled mainly for the same use (pain), the same class first. Pain lists all 80 medicines labeled for it, by any route. The first 8 are below. They are listed as records, not as substitutes: whether one can replace another is a prescriber's decision.
| Medicine | Shared indication | Generic labelers (oral) | Pharmacy cost | Shortage |
|---|---|---|---|---|
| Ibuprofen | Pain, Cough and cold, Fever | 273 labelers | $0.0573 per tablet 800 mg tablet | No current entry |
| Acetaminophen | Pain, Cough and cold, Fever | 79 labelers | $0.0339 per unit 500 mg caplet | No current entry |
| Naproxen | Pain, Cough and cold, Fever | 146 labelers | $0.0565 per tablet 500 mg tablet | No current entry |
| Acetaminophen and hydrocodone | Pain | 38 labelers | $0.152 per tablet 10-325 mg tablet | No current entry |
| Diclofenac | Pain | 67 labelers | $0.0619 per tablet 75 mg tablet | A presentation being discontinued |
| Oxycodone | Pain | 34 labelers | $0.0884 per tablet 5 mg tablet | No current entry |
| Acetaminophen and oxycodone | Pain | 30 labelers | $0.183 per tablet 7.5-325 mg tablet | A presentation being discontinued |
| Tramadol | Pain | 40 labelers | $0.0248 per tablet 50 mg tablet | No current entry |
Source: FDA drug labels (indications), NDC Directory, NADAC of October 7, 2026, FDA shortages (October 8, 2026)
How does aspirin compare with medicines for the same use?
10 side-by-side pages set aspirin beside a medicine whose label shares a use: approvals, generics, pharmacy cost, warnings and supply.
What next?
- Aspirin side effects
- the label's list beside FAERS reports
- Aspirin shortage record
- every presentation, company and date
- Check an interaction
- what two or more labels say about each other