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What the FDA labels say about taking them together

Aspirin and monomethyl fumarate

Monomethyl fumarate's FDA label of July 16, 2026 names aspirin in its warnings and precautions section; the aspirin label PlainMeds reads does not name monomethyl fumarate. The monomethyl fumarate label: “Studies with dimethyl fumarate show that administration of non-enteric coated aspirin (up to a dose of 325 mg) 30 minutes prior to dosing may reduce the incidence or severity of flushing.”

Check it at the source: the aspirin FDA label on DailyMed (effective September 9, 2025); the monomethyl fumarate FDA label on DailyMed (effective July 16, 2026, Banner Life Sciences LLC).

What does the aspirin label say about monomethyl fumarate?

Aspirin's label (effective September 9, 2025) does not name monomethyl fumarate in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Medique Products Aspirin), Unifirst First Aid Corporation, effective September 9, 2025 (SPL set 9b28fed0-a993-ca72-e053-2995a90ac7fd), via openFDA; the full label on DailyMed

What does the monomethyl fumarate label say about aspirin?

Monomethyl fumarate label, warnings and precautions

Studies with dimethyl fumarate show that administration of non-enteric coated aspirin (up to a dose of 325 mg) 30 minutes prior to dosing may reduce the incidence or severity of flushing [see Clinical Pharmacology ( 12.3 )].

Source: FDA drug label (BAFIERTAM), Banner Life Sciences LLC, effective July 16, 2026 (SPL set a161f9d4-70f1-4097-957a-eafb35d3274f), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

0Aspirin generic labelers
0Monomethyl fumarate generic labelers
AspirinMonomethyl fumarate
Labeled forPain, Cough and cold, FeverMultiple sclerosis
Boxed warningNoNo
Pharmacy cost (NADAC)$0.0142 per tablet 81 mg tabletn/a
Shortage nowA presentation being discontinuedNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?