What the FDA labels say about taking them together
Aspirin and nizatidine
Nizatidine's FDA label of January 2, 2025 names aspirin in its drug interactions section; the aspirin label PlainMeds reads does not name nizatidine. The nizatidine label: “In patients given very high doses (3,900 mg) of aspirin daily, increases in serum salicylate levels were seen when nizatidine, 150 mg b.i.d., was administered concurrently.”
Check it at the source: the aspirin FDA label on DailyMed (effective September 9, 2025); the nizatidine FDA label on DailyMed (effective January 2, 2025, Epic Pharma, LLC).
What does the aspirin label say about nizatidine?
Aspirin's label (effective September 9, 2025) does not name nizatidine in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Medique Products Aspirin), Unifirst First Aid Corporation, effective September 9, 2025 (SPL set 9b28fed0-a993-ca72-e053-2995a90ac7fd), via openFDA; the full label on DailyMed
What does the nizatidine label say about aspirin?
Nizatidine label, drug interactionsIn patients given very high doses (3,900 mg) of aspirin daily, increases in serum salicylate levels were seen when nizatidine, 150 mg b.i.d., was administered concurrently.
Source: FDA drug label (Nizatidine), Epic Pharma, LLC, effective January 2, 2025 (SPL set e9957997-8b85-48a0-9bb3-b878cb223236), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Aspirin | Nizatidine | |
|---|---|---|
| Labeled for | Pain, Cough and cold, Fever | Acid reflux and ulcers |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.0142 per tablet 81 mg tablet | $0.804 per capsule 150 mg capsule |
| Shortage now | A presentation being discontinued | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once