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What the FDA labels say about taking them together

Aspirin and triamcinolone

Triamcinolone's FDA label (Triesence) of June 5, 2026 names aspirin in its drug interactions section; the aspirin label PlainMeds reads does not name triamcinolone. The triamcinolone label: “Nonsteroidal anti-inflammatory drugs (NSAIDs) Concomitant use of aspirin and corticosteroids increases the risk of gastrointestinal side effects.”

Check it at the source: the aspirin FDA label on DailyMed (effective September 9, 2025); the triamcinolone FDA label on DailyMed (effective January 28, 2026, E. Fougera & Co. a division of Fougera Pharmaceuticals, LLC).

What does the aspirin label say about triamcinolone?

Aspirin's label (effective September 9, 2025) does not name triamcinolone in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Medique Products Aspirin), Unifirst First Aid Corporation, effective September 9, 2025 (SPL set 9b28fed0-a993-ca72-e053-2995a90ac7fd), via openFDA; the full label on DailyMed

What does the triamcinolone label say about aspirin?

Triesence label (Harrow Eye, LLC, June 5, 2026), drug interactions

NSAIDs including aspirin and salicylates: Concomitant use of aspirin or other non-steroidal antiinflammatory agents and corticosteroids increases the risk of gastrointestinal side effects.

Zilretta label (Pacira Pharmaceuticals, Inc., June 3, 2026), drug interactions

Nonsteroidal anti-inflammatory drugs (NSAIDs) Concomitant use of aspirin (or other nonsteroidal anti-inflammatory drugs) and corticosteroids increases the risk of gastrointestinal side effects.

Source: FDA drug label (Triesence, NDA022048), Harrow Eye, LLC, effective June 5, 2026 (SPL set 2267978c-72ad-9229-e063-6394a90a09d0), via openFDA

Source: FDA drug label (Zilretta, NDA208845), Pacira Pharmaceuticals, Inc., effective June 3, 2026 (SPL set cd5c4673-21f2-4126-9556-da847b3a228b), via openFDA

Source: FDA drug label (triamcinolone acetonide), E. Fougera & Co. a division of Fougera Pharmaceuticals, LLC, effective January 28, 2026 (SPL set 92a1ded0-8e1a-4994-9c8a-89e84fc85c94), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

0Aspirin generic labelers
73Triamcinolone generic labelers
AspirinTriamcinolone
Labeled forPain, Cough and cold, FeverAsthma, Eczema (atopic dermatitis), Anemia, Leukemia, lymphoma and myeloma, Allergies, Fever, Pain, Osteoarthritis
Boxed warningNoNo
Pharmacy cost (NADAC)$0.0142 per tablet 81 mg tablet$0.0452 per gram 0.1% cream
Shortage nowA presentation being discontinuedListed; available

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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