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What the FDA labels say about taking them together

Aspirin and icosapent

Icosapent's FDA label of July 9, 2026 names aspirin in its warnings and precautions section; the aspirin label PlainMeds reads does not name icosapent. The icosapent label: “The incidence of bleeding was greater in patients receiving concomitant antithrombotic medications, such as aspirin, clopidogrel, or warfarin.”

Check it at the source: the aspirin FDA label on DailyMed (effective September 9, 2025); the icosapent FDA label on DailyMed (effective July 9, 2026, Hikma Pharmaceuticals USA Inc.).

What does the aspirin label say about icosapent?

Aspirin's label (effective September 9, 2025) does not name icosapent in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Medique Products Aspirin), Unifirst First Aid Corporation, effective September 9, 2025 (SPL set 9b28fed0-a993-ca72-e053-2995a90ac7fd), via openFDA; the full label on DailyMed

What does the icosapent label say about aspirin?

Icosapent label, warnings and precautions

The incidence of bleeding was greater in patients receiving concomitant antithrombotic medications, such as aspirin, clopidogrel, or warfarin.

Source: FDA drug label (Icosapent Ethyl), Hikma Pharmaceuticals USA Inc., effective July 9, 2026 (SPL set e3d38d1d-fbe7-413d-849a-675e7dfa9b0a), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

0Aspirin generic labelers
18Icosapent generic labelers
AspirinIcosapent
Labeled forPain, Cough and cold, FeverHigh triglycerides
Boxed warningNoNo
Pharmacy cost (NADAC)$0.0142 per tablet 81 mg tablet$0.441 per capsule 1 gram capsule
Shortage nowA presentation being discontinuedA presentation being discontinued

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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