Original analyses
PlainMeds research
12 original analyses from FDA and CMS files, each leading with its finding, with its method, limits and data.
Every page
- Brand vs generic: what pharmacies pay for the same strength
- Across 367 strengths that NADAC prices as both a brand and a generic, pharmacies paid a median 20.0x more per unit for the brand (survey of …
- Brands whose listed protections end by 2028, with no generic approved
- 29 medicines with no approved generic application have their last Orange Book patent or exclusivity ending between 2026 and 2028.
- First generics approved in 2025 and 2026
- 58 medicines got their first approved generic in 2025 or 2026 (Drugs@FDA); 12 of them already have a generic price in the NADAC survey of …
- Generic competition by drug class
- Of 224 FDA pharmacologic classes with three or more medicines, 47 have every member listed from at least one generic labeler and 38 have …
- Generic medicines listed by only one or two makers
- 101 generic-only medicines are listed in FDA's NDC Directory by just one or two labelers under generic applications; …
- Medicines first approved since 2024
- 106 medicines on this site had their first FDA approval (an original NDA or BLA) on or after January 1, 2024; …
- Medicines with a boxed warning
- 664 of the 2102 medicines with a current FDA label on this site have a boxed warning on at least one of their labels (for some, only one …
- The largest changes in what pharmacies pay, over 12 months
- Of 3,213 NADAC descriptions priced a year apart, 1,010 rose and 2,151 fell; the largest rise is Imiquimod 3.75% cream pump (+363.8%) and …
- The medicines other labels name most
- Phenytoin is named in the interaction, contraindication or boxed-warning sections of 290 other medicines' FDA labels, more than any other.
- The medicines with the most FAERS reports
- Adalimumab has the most FAERS reports of any medicine on this site (712,308 through 2026-07-30); …
- Which medicines are in shortage now
- 54 medicines have at least one presentation listed as in shortage in the FDA Drug Shortage Database (updated October 6, 2026), 371 …
- Why medicines were recalled, 2024 to 2026
- 1259 FDA drug recall entries since January 2024 name a medicine on this site; the most common reason is contamination or sterility (394).
Source: openFDA (FDA labels, NDC Directory, Drugs@FDA, Orange Book, shortages, recalls, FAERS) and CMS NADAC, read October 8, 2026