Verapamil and Aspirin Interaction
Drug interaction information between Verapamil and Aspirin.
Verapamil and Aspirin have a documented minor interaction in FDA labeling.
FDA drug labeling documents a minor-severity interaction between Verapamil and Aspirin. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
Taking these two drugs together can make your blood take longer to clot than if you were taking aspirin by itself.
FDA Label Information
Aspirin: In a few reported cases, co-administration of verapamil with aspirin has led to increased bleeding times greater than observed with aspirin alone.
Verapamil Also Interacts With
- Eplerenone major
- Ezetimibe major
- Ezetimibe/Simvastatin major
- Simvastatin major
- Clarithromycin moderate
Aspirin Also Interacts With
- Atenolol major
- Fluoxetine major
- Ibandronate major
- Alendronate moderate
- Apixaban moderate
Frequently Asked Questions
What SPL severity band is on file for Verapamil + Aspirin?
Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Verapamil has 57 labeled pairs on file vs Aspirin's 47. In the minor band specifically: Verapamil has 47 (also Atorvastatin, Atenolol, Timolol, Cyclosporine); Aspirin has 32 (also Carisoprodol, Celecoxib, Colestipol, Diflunisal).
What mechanism field is on file for Verapamil and Aspirin?
Taking these two drugs together can make your blood take longer to clot than if you were taking aspirin by itself.
Verapamil carries more major-labeled pairs than Aspirin
SPL source-record counts only. This page's band is minor · classes on file: Verapamil (Calcium Channel Blocker); Aspirin (Antiplatelet / NSAID).
Verapamil has 4 major-labeled pairs vs Aspirin's 3. This page itself is in the minor band, not the major band.
4 major · 6 moderate · 47 minor · 57 total
- Other minor peers for Verapamil
- Atorvastatin
- Atenolol
- Timolol
- Cyclosporine
3 major · 12 moderate · 32 minor · 47 total
- Other minor peers for Aspirin
- Carisoprodol
- Celecoxib
- Colestipol
- Diflunisal
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.