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What the FDA labels say about taking them together

Aspirin and eptifibatide

Eptifibatide's FDA label of May 28, 2021 names aspirin in its drug interactions section; the aspirin label PlainMeds reads does not name eptifibatide. The eptifibatide label: “Coadministration of antiplatelet agents, thrombolytics, heparin, aspirin, and chronic NSAID use increases the risk of bleeding.”

Check it at the source: the aspirin FDA label on DailyMed (effective September 9, 2025); the eptifibatide FDA label on DailyMed (effective May 28, 2021, Mylan Institutional LLC).

What does the aspirin label say about eptifibatide?

Aspirin's label (effective September 9, 2025) does not name eptifibatide in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Medique Products Aspirin), Unifirst First Aid Corporation, effective September 9, 2025 (SPL set 9b28fed0-a993-ca72-e053-2995a90ac7fd), via openFDA; the full label on DailyMed

What does the eptifibatide label say about aspirin?

Eptifibatide label, drug interactions

Coadministration of antiplatelet agents, thrombolytics, heparin, aspirin, and chronic NSAID use increases the risk of bleeding.

Source: FDA drug label (Eptifibatide), Mylan Institutional LLC, effective May 28, 2021 (SPL set 88a37f9c-496b-4a6b-9665-4550abba04f1), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

0Aspirin generic labelers
8Eptifibatide generic labelers
AspirinEptifibatide
Labeled forPain, Cough and cold, FeverHeart attack and coronary artery disease
Boxed warningNoNo
Pharmacy cost (NADAC)$0.0142 per tablet 81 mg tabletn/a
Shortage nowA presentation being discontinuedNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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