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What the FDA labels say about taking them together

Aspirin and ibandronate

Ibandronate's FDA label of March 18, 2026 names aspirin in its drug interactions section; the aspirin label PlainMeds reads does not name ibandronate. The ibandronate label: “Do not take within 60 minutes of dosing. Use caution when co-prescribing aspirin/nonsteroidal anti-inflammatory drugs that may worsen gastrointestinal irritation.”

Check it at the source: the aspirin FDA label on DailyMed (effective September 9, 2025); the ibandronate FDA label on DailyMed (effective March 18, 2026, Aurobindo Pharma Limited).

What does the aspirin label say about ibandronate?

Aspirin's label (effective September 9, 2025) does not name ibandronate in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Medique Products Aspirin), Unifirst First Aid Corporation, effective September 9, 2025 (SPL set 9b28fed0-a993-ca72-e053-2995a90ac7fd), via openFDA; the full label on DailyMed

What does the ibandronate label say about aspirin?

Ibandronate label, drug interactions

Do not take within 60 minutes of dosing. ( 7.1 ) Use caution when co-prescribing aspirin/nonsteroidal anti-inflammatory drugs that may worsen gastrointestinal irritation.

Source: FDA drug label (Ibandronate Sodium), Aurobindo Pharma Limited, effective March 18, 2026 (SPL set 86c0b4ae-5e38-4efe-88af-50ac560e294f), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

0Aspirin generic labelers
9Ibandronate generic labelers
AspirinIbandronate
Labeled forPain, Cough and cold, FeverOsteoporosis
Boxed warningNoNo
Pharmacy cost (NADAC)$0.0142 per tablet 81 mg tablet$2.68 per tablet 150 mg tablet
Shortage nowA presentation being discontinuedNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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