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What the FDA labels say about taking them together

Aspirin and prasugrel

Prasugrel's FDA label of February 11, 2025 names aspirin in its drug interactions section; the aspirin label PlainMeds reads does not name prasugrel.

Check it at the source: the aspirin FDA label on DailyMed (effective September 9, 2025); the prasugrel FDA label on DailyMed (effective February 11, 2025, Panacea Biotec Limited).

What does the aspirin label say about prasugrel?

Aspirin's label (effective September 9, 2025) does not name prasugrel in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Medique Products Aspirin), Unifirst First Aid Corporation, effective September 9, 2025 (SPL set 9b28fed0-a993-ca72-e053-2995a90ac7fd), via openFDA; the full label on DailyMed

What does the prasugrel label say about aspirin?

Prasugrel label, drug interactions

Prasugrel tablets can be administered with aspirin (75 mg to 325 mg per day), heparin, GPIIb/IIIa inhibitors, statins, digoxin, and drugs that elevate gastric pH, including proton pump inhibitors and H 2 blockers [see Clinical Pharmacology ( 12.3 )].

Prasugrel label, warnings and precautions

Aspirin and heparin were commonly used in TRITON-TIMI 38 [see Drug Interactions ( 7.1 , 7.2 , 7.4 ), and Clinical Studies ( 14 )].

Source: FDA drug label (Effient, NDA022307), Cosette Pharmaceuticals, Inc., effective September 7, 2022 (SPL set 69ea2d58-5353-4222-b61f-cab976fa7e5e), via openFDA

Source: FDA drug label (PRASUGREL), Panacea Biotec Limited, effective February 11, 2025 (SPL set 944c195a-de24-a44c-8baa-84b624b5ddcb), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

0Aspirin generic labelers
10Prasugrel generic labelers
AspirinPrasugrel
Labeled forPain, Cough and cold, FeverHeart attack and coronary artery disease, Angina
Boxed warningNoYes
Pharmacy cost (NADAC)$0.0142 per tablet 81 mg tablet$0.263 per tablet 10 mg tablet
Shortage nowA presentation being discontinuedNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?