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What the FDA labels say about taking them together

Abrocitinib and aspirin

Abrocitinib's FDA label of September 9, 2026 names aspirin in its contraindications section; the aspirin label PlainMeds reads does not name abrocitinib. The abrocitinib label: “Intervention; CIBINQO is contraindicated in patients taking antiplatelet drugs, except for low-dose aspirin (≤81 mg daily), during the first 3 months of treatment.”

Check it at the source: the abrocitinib FDA label on DailyMed (effective September 9, 2026, Pfizer Laboratories Div Pfizer Inc); the aspirin FDA label on DailyMed (effective September 9, 2025).

What does the abrocitinib label say about aspirin?

Abrocitinib label, contraindications

CONTRAINDICATIONS CIBINQO is contraindicated in patients taking antiplatelet therapies, except for low-dose aspirin (≤81 mg daily), during the first 3 months of treatment [see Warnings and Precautions (5.7), Drug Interactions (7.2), and Clinical Pharmacology (12.2) ].

Abrocitinib label, drug interactions

Intervention; CIBINQO is contraindicated in patients taking antiplatelet drugs, except for low-dose aspirin (≤81 mg daily), during the first 3 months of treatment [see ].

Source: FDA drug label (Cibinqo), Pfizer Laboratories Div Pfizer Inc, effective September 9, 2026 (SPL set 3f6d6fcd-e9f9-42c8-bfa2-bb2cfc9ed258), via openFDA; the full label on DailyMed

What does the aspirin label say about abrocitinib?

Aspirin's label (effective September 9, 2025) does not name abrocitinib in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Medique Products Aspirin), Unifirst First Aid Corporation, effective September 9, 2025 (SPL set 9b28fed0-a993-ca72-e053-2995a90ac7fd), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

0Abrocitinib generic labelers
0Aspirin generic labelers
AbrocitinibAspirin
Labeled forEczema (atopic dermatitis)Pain, Cough and cold, Fever
Boxed warningYesNo
Pharmacy cost (NADAC)$197.09 per tablet 100 mg tablet$0.0142 per tablet 81 mg tablet
Shortage nowNo current entryA presentation being discontinued

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?