If someone is having a severe reaction right now
Call 911 or your local emergency number. For poisoning or overdose, call the U.S. Poison Help line at 1-800-222-1222 (24/7). This checker is educational FDA-linked data; it does not replace emergency care or a clinician.
Drug Interaction Checker
Enter your medications to check for potential interactions. Add two or more drugs, then click "Check Interactions." Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
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Important: This tool checks for known interactions in our database. It may not include all possible interactions. Always consult your doctor or pharmacist before starting, stopping, or changing medications.