FDA Drug Shortage Database
Drug shortages now
54 medicines have at least one presentation the FDA Drug Shortage Database lists as limited or unavailable (updated October 6, 2026), 371 presentations in all; lisdexamfetamine has the most (34), then amphetamine and dextroamphetamine (28) and carboplatin (25).
Which medicines are in shortage?
| Medicine | Limited or unavailable | First posted | Companies | Generic labelers |
|---|---|---|---|---|
| Lisdexamfetamine | 34 | July 14, 2023 | 14 | 19 labelers |
| Amphetamine and dextroamphetamine | 28 | October 12, 2022 | 11 | 25 labelers |
| Carboplatin | 25 | April 28, 2023 | 9 | 10 labelers |
| Lidocaine | 15 | February 22, 2012 | 9 | 81 labelers |
| Methylphenidate | 15 | July 26, 2023 | 7 | 31 labelers |
| Ropivacaine | 15 | March 23, 2018 | 5 | 18 labelers |
| Methylprednisolone | 14 | December 15, 2021 | 5 | 35 labelers |
| Ketorolac | 13 | March 23, 2018 | 8 | 60 labelers |
| Furosemide | 12 | April 7, 2020 | 9 | 52 labelers |
| Hydromorphone | 12 | October 31, 2017 | 5 | 13 labelers |
| Midazolam | 12 | April 2, 2020 | 6 | 22 labelers |
| Morphine | 12 | October 31, 2017 | 7 | 22 labelers |
| Quinapril | 12 | January 19, 2023 | 4 | 9 labelers |
| Dexmedetomidine | 11 | April 10, 2020 | 17 | 23 labelers |
| Lorazepam | 10 | May 3, 2018 | 4 | 36 labelers |
| Bupivacaine | 8 | February 20, 2018 | 7 | 26 labelers |
| Epinephrine and lidocaine | 8 | February 22, 2012 | 1 | 17 labelers |
| Fentanyl | 7 | January 1, 2012 | 3 | 6 labelers |
| Methotrexate | 7 | March 13, 2023 | 5 | 29 labelers |
| Promethazine | 7 | November 21, 2023 | 2 | 47 labelers |
| Rifampin | 7 | February 17, 2021 | 5 | 13 labelers |
| Atropine | 6 | January 1, 2012 | 8 | 22 labelers |
| Clindamycin | 6 | March 21, 2023 | 5 | 60 labelers |
| Dextrose | 5 | January 13, 2022 | 6 | 7 labelers |
| Azacitidine | 4 | December 18, 2020 | 9 | 20 labelers |
| Cefotaxime | 4 | February 17, 2015 | 2 | 1 labeler |
| Ifosfamide | 4 | June 12, 2026 | 4 | 2 labelers |
| Sodium bicarbonate | 4 | March 1, 2017 | 5 | 22 labelers |
| Dopamine | 3 | November 6, 2017 | 3 | 4 labelers |
| Etomidate | 3 | October 5, 2022 | 6 | 10 labelers |
| Heparin | 3 | November 14, 2017 | 4 | 18 labelers |
| Hydrochlorothiazide and quinapril | 3 | January 19, 2023 | 2 | 4 labelers |
| Liraglutide | 3 | July 18, 2023 | 4 | 9 labelers |
| Metronidazole | 3 | January 13, 2022 | 3 | 55 labelers |
| Penicillin g benzathine | 3 | April 26, 2023 | 2 | none listed |
| Remifentanil | 3 | June 28, 2022 | 3 | 2 labelers |
| Rocuronium | 3 | February 15, 2023 | 11 | 26 labelers |
| Sufentanil | 3 | May 3, 2022 | 2 | 1 labeler |
| Water | 3 | November 23, 2021 | 7 | 11 labelers |
| Alanine, arginine and 16 other ingredients | 2 | December 8, 2020 | 1 | none listed |
| Dexamethasone | 2 | February 8, 2019 | 5 | 60 labelers |
| Flurazepam | 2 | August 3, 2022 | 2 | 1 labeler |
| Hydroxocobalamin | 2 | November 4, 2024 | 2 | 1 labeler |
| Sodium acetate | 2 | February 3, 2016 | 5 | 5 labelers |
| Technetium tc 99m pyrophosphate | 2 | December 27, 2023 | 1 | none listed |
| Alanine, arginine and 13 other ingredients | 1 | December 8, 2020 | 1 | none listed |
| Bacitracin | 1 | March 3, 2025 | 1 | none listed |
| Clonazepam | 1 | March 10, 2023 | 6 | 31 labelers |
| Dobutamine | 1 | November 6, 2017 | 3 | 4 labelers |
| Isocarboxazid | 1 | April 16, 2026 | 1 | none listed |
| Pentostatin | 1 | August 27, 2026 | 1 | none listed |
| Propranolol | 1 | October 31, 2023 | 2 | 42 labelers |
| Riluzole | 1 | January 26, 2024 | 1 | 5 labelers |
| Sodium pyrophosphate and stannous | 1 | December 27, 2023 | 1 | none listed |
Each medicine links to its shortage record: every presentation, company, reason and date, grouped as short now, listed but available, and resolved.
This is the FDA's own list: shortages the agency confirms, with the reason and dates the makers report. The list the American Society of Health-System Pharmacists keeps is broader and counts more medicines; it is not reproduced here.
Source: FDA Drug Shortage Database via openFDA, updated October 6, 2026
What next?
- The shortage analysis
- counts, method and the data
- The longest current shortages
- by first posting