Fluvoxamine and Aspirin Interaction
Drug interaction information between Fluvoxamine and Aspirin.
Fluvoxamine and Aspirin have a documented minor interaction in FDA labeling.
FDA drug labeling documents a minor-severity interaction between Fluvoxamine and Aspirin. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
Both of these medications can interfere with how your blood clots. Taking them together increases your risk of bruising or bleeding.
FDA Label Information
Warfarin and Other Drugs That Interfere With Hemostasis (NSAIDs, Aspirin, etc.): See WARNINGS AND PRECAUTIONS ( 5.9 , 5.11 ) .
Fluvoxamine Also Interacts With
- Tizanidine major
- Lithium moderate
- Phenelzine moderate
- Tasimelteon moderate
- Metoprolol minor
Aspirin Also Interacts With
- Atenolol major
- Fluoxetine major
- Ibandronate major
- Alendronate moderate
- Apixaban moderate
Frequently Asked Questions
What SPL severity band is on file for Fluvoxamine + Aspirin?
Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Aspirin has 47 labeled pairs on file vs Fluvoxamine's 40. In the minor band specifically: Fluvoxamine has 36 (also Metoprolol, Omeprazole, Fluoxetine, Propranolol); Aspirin has 32 (also Carisoprodol, Celecoxib, Colestipol, Diflunisal).
What mechanism field is on file for Fluvoxamine and Aspirin?
Both of these medications can interfere with how your blood clots. Taking them together increases your risk of bruising or bleeding.
Aspirin carries more major-labeled pairs than Fluvoxamine
SPL source-record counts only. This page's band is minor · classes on file: Fluvoxamine (Selective Serotonin Reuptake Inhibitor (SSRI)); Aspirin (Antiplatelet / NSAID).
Aspirin has 3 major-labeled pairs vs Fluvoxamine's 1. This page itself is in the minor band, not the major band.
1 major · 3 moderate · 36 minor · 40 total
- Other minor peers for Fluvoxamine
- Metoprolol
- Omeprazole
- Fluoxetine
- Propranolol
3 major · 12 moderate · 32 minor · 47 total
- Other minor peers for Aspirin
- Carisoprodol
- Celecoxib
- Colestipol
- Diflunisal
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.