What the FDA labels say about taking them together
Aspirin and montelukast
Montelukast's FDA label of April 30, 2025 names aspirin in its warnings and precautions section; the aspirin label PlainMeds reads does not name montelukast. The montelukast label: “Patients with known aspirin sensitivity should continue to avoid aspirin or non-steroidal anti-inflammatory agents while taking SINGULAIR.”
Check it at the source: the aspirin FDA label on DailyMed (effective September 9, 2025); the montelukast FDA label on DailyMed (effective April 30, 2025, Organon LLC).
What does the aspirin label say about montelukast?
Aspirin's label (effective September 9, 2025) does not name montelukast in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Medique Products Aspirin), Unifirst First Aid Corporation, effective September 9, 2025 (SPL set 9b28fed0-a993-ca72-e053-2995a90ac7fd), via openFDA; the full label on DailyMed
What does the montelukast label say about aspirin?
Montelukast label, warnings and precautionsPatients with known aspirin sensitivity should continue to avoid aspirin or non-steroidal anti-inflammatory agents while taking SINGULAIR ( 5.4 ).
Source: FDA drug label (SINGULAIR), Organon LLC, effective April 30, 2025 (SPL set 482dcc92-b47f-4ea6-854a-f5ac2aea7842), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Aspirin | Montelukast | |
|---|---|---|
| Labeled for | Pain, Cough and cold, Fever | Asthma, Allergies |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $0.0142 per tablet 81 mg tablet | $0.0419 per tablet 10 mg tablet |
| Shortage now | A presentation being discontinued | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once