What the FDA labels say about taking them together
Aspirin and tenecteplase
Tenecteplase's FDA label of December 15, 2025 names aspirin in its warnings and precautions section; the aspirin label PlainMeds reads does not name tenecteplase. The tenecteplase label: “Because heparin, aspirin, or TNKase may cause bleeding complications, carefully monitor for bleeding, especially at arterial puncture sites.”
Check it at the source: the aspirin FDA label on DailyMed (effective September 9, 2025); the tenecteplase FDA label on DailyMed (effective December 15, 2025, Genentech, Inc.).
What does the aspirin label say about tenecteplase?
Aspirin's label (effective September 9, 2025) does not name tenecteplase in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Medique Products Aspirin), Unifirst First Aid Corporation, effective September 9, 2025 (SPL set 9b28fed0-a993-ca72-e053-2995a90ac7fd), via openFDA; the full label on DailyMed
What does the tenecteplase label say about aspirin?
Tenecteplase label, warnings and precautionsBecause heparin, aspirin, or TNKase may cause bleeding complications, carefully monitor for bleeding, especially at arterial puncture sites.
Source: FDA drug label (TNKase), Genentech, Inc., effective December 15, 2025 (SPL set e647640d-c395-4b4b-a0be-1162f9c21d84), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Aspirin | Tenecteplase | |
|---|---|---|
| Labeled for | Pain, Cough and cold, Fever | Heart attack and coronary artery disease |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.0142 per tablet 81 mg tablet | n/a |
| Shortage now | A presentation being discontinued | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once