What the FDA labels say about taking them together
Anagrelide and aspirin
Anagrelide's FDA label of April 8, 2026 names aspirin in its drug interactions section; the aspirin label PlainMeds reads does not name anagrelide. The anagrelide label: “Use of concomitant AGRYLIN and aspirin increased major hemorrhagic events in a postmarketing study.”
Check it at the source: the anagrelide FDA label on DailyMed (effective April 8, 2026, Takeda Pharmaceuticals America, Inc.); the aspirin FDA label on DailyMed (effective September 9, 2025).
What does the anagrelide label say about aspirin?
Anagrelide label, drug interactionsDRUG INTERACTIONS Other PDE3 inhibitors: Exacerbation of inotropic effects. ( 7.2 ) Aspirin and Drugs that Increase Bleeding Risk:
Anagrelide label, warnings and precautionsUse of concomitant AGRYLIN and aspirin increased major hemorrhagic events in a postmarketing study.
Source: FDA drug label (Agrylin), Takeda Pharmaceuticals America, Inc., effective April 8, 2026 (SPL set cb960074-99c1-4a73-941f-f0644a7ec219), via openFDA; the full label on DailyMed
What does the aspirin label say about anagrelide?
Aspirin's label (effective September 9, 2025) does not name anagrelide in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Medique Products Aspirin), Unifirst First Aid Corporation, effective September 9, 2025 (SPL set 9b28fed0-a993-ca72-e053-2995a90ac7fd), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Anagrelide | Aspirin | |
|---|---|---|
| Labeled for | n/a | Pain, Cough and cold, Fever |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.729 per capsule 0.5 mg capsule | $0.0142 per tablet 81 mg tablet |
| Shortage now | A presentation being discontinued | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once