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What the FDA labels say about taking them together

Aspirin and rimantadine

Rimantadine's FDA label of December 31, 2023 names aspirin in its drug interactions section; the aspirin label PlainMeds reads does not name rimantadine. The rimantadine label: “Peak plasma concentrations and AUC of rimantadine were reduced approximately 10% in the presence of aspirin.”

Check it at the source: the aspirin FDA label on DailyMed (effective September 9, 2025); the rimantadine FDA label on DailyMed (effective December 31, 2023, Amneal Pharmaceuticals of New York LLC).

What does the aspirin label say about rimantadine?

Aspirin's label (effective September 9, 2025) does not name rimantadine in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Medique Products Aspirin), Unifirst First Aid Corporation, effective September 9, 2025 (SPL set 9b28fed0-a993-ca72-e053-2995a90ac7fd), via openFDA; the full label on DailyMed

What does the rimantadine label say about aspirin?

Rimantadine label, drug interactions

Peak plasma concentrations and AUC of rimantadine were reduced approximately 10% in the presence of aspirin.

Source: FDA drug label (Rimantadine Hydrochloride), ANDA076132 (Impax Labs), as published by Amneal Pharmaceuticals of New York LLC, effective December 31, 2023 (SPL set 49f7d69a-820b-4c75-a31d-b2104c019c12), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

0Aspirin generic labelers
1Rimantadine generic labelers
AspirinRimantadine
Labeled forPain, Cough and cold, FeverInfluenza
Boxed warningNoNo
Pharmacy cost (NADAC)$0.0142 per tablet 81 mg tabletn/a
Shortage nowA presentation being discontinuedNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?