What the FDA labels say about taking them together
Aspirin and vardenafil
Vardenafil's FDA label of January 5, 2026 names aspirin in its drug interactions section; the aspirin label PlainMeds reads does not name vardenafil. The vardenafil label: “Aspirin Vardenafil (10 mg and 20 mg) did not potentiate the increase in bleeding time caused by aspirin (two 81 mg tablets).”
Check it at the source: the aspirin FDA label on DailyMed (effective September 9, 2025); the vardenafil FDA label on DailyMed (effective January 5, 2026, Zydus Pharmaceuticals USA Inc.).
What does the aspirin label say about vardenafil?
Aspirin's label (effective September 9, 2025) does not name vardenafil in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Medique Products Aspirin), Unifirst First Aid Corporation, effective September 9, 2025 (SPL set 9b28fed0-a993-ca72-e053-2995a90ac7fd), via openFDA; the full label on DailyMed
What does the vardenafil label say about aspirin?
Vardenafil label, drug interactionsAspirin Vardenafil (10 mg and 20 mg) did not potentiate the increase in bleeding time caused by aspirin (two 81 mg tablets).
Vardenafil label, warnings and precautionsThere is no clinical evidence of any additive prolongation of the bleeding time when vardenafil is administered with aspirin.
Source: FDA drug label (VARDENAFIL), Zydus Pharmaceuticals USA Inc., effective January 5, 2026 (SPL set 5876e062-e604-42a7-99c3-5da30b8dac06), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Aspirin | Vardenafil | |
|---|---|---|
| Labeled for | Pain, Cough and cold, Fever | Erectile dysfunction |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.0142 per tablet 81 mg tablet | $2.79 per tablet 20 mg tablet |
| Shortage now | A presentation being discontinued | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once