What the FDA labels say about taking them together
Aspirin and diroximel fumarate
Diroximel fumarate's FDA label of May 29, 2025 names aspirin in its warnings and precautions section; the aspirin label PlainMeds reads does not name diroximel fumarate. The diroximel fumarate label: “Studies with dimethyl fumarate show that administration of non-enteric coated aspirin (up to a dose of 325 mg) 30 minutes prior to dosing may reduce the incidence or severity of flushing.”
Check it at the source: the aspirin FDA label on DailyMed (effective September 9, 2025); the diroximel fumarate FDA label on DailyMed (effective May 29, 2025, Biogen Inc.).
What does the aspirin label say about diroximel fumarate?
Aspirin's label (effective September 9, 2025) does not name diroximel fumarate in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Medique Products Aspirin), Unifirst First Aid Corporation, effective September 9, 2025 (SPL set 9b28fed0-a993-ca72-e053-2995a90ac7fd), via openFDA; the full label on DailyMed
What does the diroximel fumarate label say about aspirin?
Diroximel fumarate label, warnings and precautionsStudies with dimethyl fumarate show that administration of non-enteric coated aspirin (up to a dose of 325 mg) 30 minutes prior to dosing may reduce the incidence or severity of flushing [see Clinical Pharmacology ( 12.3 )].
Source: FDA drug label (Vumerity), Biogen Inc., effective May 29, 2025 (SPL set 2d74414f-6b83-4ea2-9a95-3cecabbce774), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Aspirin | Diroximel fumarate | |
|---|---|---|
| Labeled for | Pain, Cough and cold, Fever | Multiple sclerosis |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.0142 per tablet 81 mg tablet | n/a |
| Shortage now | A presentation being discontinued | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once