Medication class
Antibiotics
Anti-infective drugs that treat bacterial infections, including penicillins, cephalosporins, macrolides, and fluoroquinolones.
Data updated 2026-05-15
- 56
- Medications
- 40
- With a generic
- 62%
- Avg generic savings
- 4
- In active shortage
Drug class assignments follow the FDA openFDA therapeutic classification, clinical details are drawn from FDA Structured Product Labeling via DailyMed, and unit-price comparisons use CMS National Average Drug Acquisition Cost data. See the full sources below.
Inventory versus report volume
Antibiotics is inventory #2 of 22 (56 drugs) ≠ FAERS-volume #14. Nationally Mental Health is inventory #1 of 22 (77 drugs) ≠ Pain Relief FAERS-volume #1 at inventory #3.
- #2
- inventory
- 56
- tracked drugs
- #14
- FAERS volume
- #1
- Pain Relief FAERS nationally
According to FDA FAERS report totals and openFDA class inventory compiled on /methodology. Class size is not the same map as report volume. This page is for informational purposes only and is not medical advice.
This class - generic availability cut
Exclusive DISTINCT-drug split of 56 medicines in Antibiotics. Orthogonal to inventory vs FAERS dual and to the NADAC cost ChartBar.
fidaxomicin tops Antibiotics NADAC at $239.00/unit
Top 10 acquisition costs in this class (CMS NADAC)
- fidaxomicin
fidaxomicin
$239 per unit
- delafloxacin $72
delafloxacin
$72 per unit
- clindamycin $59
clindamycin
$59 per unit
- fosfomycin $42
fosfomycin
$42 per unit
- ertapenem $38
ertapenem
$38 per unit
- daptomycin $18
daptomycin
$18 per unit
- meropenem $7
meropenem
$7 per unit
- cefixime $6
cefixime
$6 per unit
- amoxicillin/clavulanate $6
amoxicillin/clavulanate
$6 per unit
- nitrofurantoin $4
nitrofurantoin
$4 per unit
What this shows fidaxomicin is the costliest in this class at $239.00/unit; generics in the same class run a fraction of that.
Antibiotics · #2 inventory of 22 therapeutic classes
20 classes have fewer tracked drugs; percentile 91 among PlainMeds categories.
Antibiotics vs all classes by tracked-drug count
Where this class's inventory sits among every PlainMeds therapeutic category
56 2nd of 22 higher than 20 of 22 classes
Classes, banded by tracked-drug inventory
Each bar is a band; taller bars hold more classes. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source PlainMeds openFDA therapeutic-class inventory · 2026-05-15
amikacin
Amikin
Amikacin is an antibiotic medicine.
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amoxicillin
Amoxil
Amoxicillin and Clavulanate Potassium is a combination medicine used to fight bacterial infections.
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amoxicillin/clavulanate
Augmentin
Augmentin is a combination of two medicines, amoxicillin and clavulanate.
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ampicillin/sulbactam
Unasyn
Unasyn is a combination of two antibiotics that fights bacteria in your body.
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azithromycin
Zithromax, Z-Pack
Azithromycin is an antibiotic that fights bacteria.
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cefazolin
Ancef, Kefzol
Cefazolin is an antibiotic medicine.
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cefdinir
Omnicef
Cefdinir is an antibiotic that fights bacteria in your body.
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cefepime
Maxipime
Cefepime is an antibiotic medicine.
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cefixime
Suprax
Cefixime is an antibiotic that fights bacteria in your body.
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cefpodoxime
Vantin
Cefpodoxime is an antibiotic that fights bacterial infections.
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ceftaroline
Teflaro
Ceftaroline (Teflaro) is an antibiotic medicine.
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ceftazidime
Fortaz
Ceftazidime is an antibiotic medicine.
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ceftazidime/avibactam
Avycaz
Avycaz is a drug that combines two medicines, ceftazidime and avibactam.
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ceftolozane/tazobactam
Zerbaxa
Zerbaxa is a combination of two antibiotics, ceftolozane and tazobactam.
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ceftriaxone
Rocephin
Ceftriaxone is an antibiotic medicine.
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cefuroxime
Ceftin, Zinacef
Cefuroxime is an antibiotic that fights bacterial infections.
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cephalexin
Keflex
Cephalexin is an antibiotic medicine.
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ciprofloxacin
Cipro
Ciprofloxacin eye drops are an antibiotic medicine.
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clarithromycin
Biaxin
Clarithromycin is an antibiotic that fights bacterial infections.
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clindamycin
Cleocin
Clindamycin phosphate topical lotion is an antibiotic medicine that you put on your skin.
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colistin
Coly-Mycin M
Cortisporin TC Otic is an ear drop medicine.
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dalbavancin
Dalvance
Dalbavancin is an antibiotic medicine.
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daptomycin
Cubicin
Daptomycin is an antibiotic medicine.
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delafloxacin
Baxdela
Baxdela is an antibiotic that fights bacteria in your body.
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dicloxacillin
Dynapen
Dicloxacillin is an antibiotic that fights bacteria in your body.
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doxycycline
Vibramycin, Doryx
Doxycycline is an antibiotic medicine.
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eravacycline
Xerava
Xerava is an antibiotic medicine.
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ertapenem
Invanz
Ertapenem is an antibiotic medicine.
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erythromycin
E-Mycin, Ery-Tab
Erythromycin Topical Solution is a medicine that you put on your skin to treat acne.
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fidaxomicin
Dificid
Fidaxomicin is an antibiotic medicine.
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fosfomycin
Monurol
Fosfomycin is an antibiotic medicine.
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gentamicin
Garamycin
Gentamicin is an antibiotic medicine.
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imipenem/cilastatin
Primaxin
Primaxin is a strong antibiotic medicine.
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lefamulin
Xenleta
Xenleta is an antibiotic medicine.
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levofloxacin
Levaquin
Levofloxacin is an antibiotic that fights bacteria in your body.
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linezolid
Zyvox
Linezolid is an antibiotic that fights bacteria in your body.
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meropenem
Merrem
Meropenem is an antibiotic medicine.
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meropenem/vaborbactam
Vabomere
Vabomere is a drug that combines two medicines to fight certain infections.
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metronidazole
Flagyl
Metronidazole is an antibiotic medicine.
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minocycline
Minocin, Solodyn
Minocycline is an antibiotic that fights bacteria in your body.
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moxifloxacin
Avelox
Moxifloxacin is an antibiotic that fights bacteria in your body.
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nitrofurantoin
Macrobid, Macrodantin
Nitrofurantoin is an antibiotic medicine.
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ofloxacin
Floxin, Ocuflox
Ofloxacin ear drops are an antibiotic medicine.
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omadacycline
Nuzyra
Nuzyra is an antibiotic medicine.
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oritavancin
Orbactiv
KIMYRSA is an antibiotic medicine.
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penicillin V
Pen-Vee K
Penicillin V is an antibiotic.
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piperacillin/tazobactam
Zosyn
Zosyn is a combination of two medicines, piperacillin and tazobactam.
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plazomicin
Zemdri
Zemdri is an antibiotic medicine.
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rifampin
Rifadin
Rifampin is an antibiotic medicine.
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sulfamethoxazole/trimethoprim
Bactrim, Septra
Sulfamethoxazole and trimethoprim is a combination antibiotic.
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tedizolid
Sivextro
Tedizolid (Sivextro) is an antibiotic medicine.
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tetracycline
Sumycin
Tetracycline is an antibiotic medicine.
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tigecycline
Tygacil
Tigecycline is an antibiotic medicine.
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tobramycin
Tobi, Nebcin
Tobramycin is an antibiotic medicine.
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trimethoprim
Primsol
This medicine contains sulfamethoxazole and trimethoprim.
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vancomycin
Vancocin
Vancomycin is a strong antibiotic.
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Antibiotics · large class with 4 active shortages
Antibiotics is inventory #2 of 22 (56 drugs) ≠ FAERS-volume #14. Nationally Mental Health is inventory #1 of 22 (77 drugs) ≠ Pain Relief FAERS-volume #1 at inventory #3. 56 medicines tracked; 40 carry a NADAC generic flag; 4 in active FDA shortage.
Classes nearest Antibiotics by inventory size
Read our methodology - how this data is sourced, computed, and verified.