Medication class

Mental Health

Medications for depression, anxiety, bipolar disorder, ADHD, and other mental health conditions, including SSRIs, SNRIs, and stimulants.

Data updated 2026-05-15

77
Medications
68
With a generic
92%
Avg generic savings
5
In active shortage

Drug class assignments follow the FDA openFDA therapeutic classification, clinical details are drawn from FDA Structured Product Labeling via DailyMed, and unit-price comparisons use CMS National Average Drug Acquisition Cost data. See the full sources below.

Inventory versus report volume

Mental Health is inventory #1 of 22 (77 drugs) ≠ FAERS-volume #2. Nationally Mental Health is inventory #1 of 22 (77 drugs) ≠ Pain Relief FAERS-volume #1 at inventory #3.

#1
inventory
77
tracked drugs
#2
FAERS volume
#1
Pain Relief FAERS nationally

According to FDA FAERS report totals and openFDA class inventory compiled on /methodology. Class size is not the same map as report volume. This page is for informational purposes only and is not medical advice.

This class - generic availability cut

Exclusive DISTINCT-drug split of 77 medicines in Mental Health. Orthogonal to inventory vs FAERS dual and to the NADAC cost ChartBar.

naltrexone tops Mental Health NADAC at $1579.00/unit

Top 10 acquisition costs in this class (CMS NADAC)

per unit

What this shows naltrexone is the costliest in this class at $1579.00/unit; generics in the same class run a fraction of that.

Source CMS National Average Drug Acquisition Cost (NADAC)

Mental Health carries the largest tracked inventory (77 medicines)

21 classes have fewer tracked drugs; percentile 95 among PlainMeds categories.

Mental Health vs all classes by tracked-drug count

Where this class's inventory sits among every PlainMeds therapeutic category

77 1st of 22 the highest of 22 classes

Classes, banded by tracked-drug inventory

Each bar is a band; taller bars hold more classes. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source PlainMeds openFDA therapeutic-class inventory · 2026-05-15

acamprosate

Campral

Acamprosate is a medicine that can help you stay away from alcohol if you are alcohol-dependent and have already stopped drinking.

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alprazolam

Xanax

Alprazolam (Xanax) is a medication that can help you with anxiety and panic disorders.

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amitriptyline

Elavil

Amitriptyline is a medicine used to treat depression.

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amphetamine/dextroamphetamine

Adderall, Adderall XR

Adderall XR is a stimulant medicine.

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aripiprazole

Abilify

Aripiprazole (Abilify) is a medicine used to treat certain mental disorders and mood problems.

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asenapine

Saphris

Asenapine (Saphris) is an antipsychotic medicine.

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atomoxetine

Strattera

Atomoxetine (Strattera) is a medicine that can help people with Attention-Deficit/Hyperactivity Disorder (ADHD).

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brexpiprazole

Rexulti

Rexulti is a medication used to treat certain mental health conditions.

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buprenorphine

Subutex, Sublocade

Buprenorphine sublingual tablets help treat opioid dependence.

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buprenorphine/naloxone

Suboxone

Suboxone film contains buprenorphine and naloxone.

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bupropion

Wellbutrin, Zyban

Bupropion is a medicine used to treat depression and prevent seasonal affective disorder (SAD).

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buspirone

BuSpar

Buspirone is a medicine that can help manage anxiety disorders.

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carbidopa/levodopa

Sinemet

This medicine contains carbidopa, levodopa, and entacapone.

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cariprazine

Vraylar

Vraylar is a medicine used to treat certain mental health conditions.

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chlorpromazine

Thorazine

Chlorpromazine is a medicine that belongs to a class of drugs called phenothiazine antipsychotics.

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citalopram

Celexa

Citalopram is a medicine used to treat depression in adults.

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clomipramine

Anafranil

Clomipramine (Anafranil) is a medicine used to treat obsessive-compulsive disorder (OCD).

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clozapine

Clozaril

Versacloz is a medicine used to treat severe schizophrenia when other medicines have not worked.

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desipramine

Norpramin

Desipramine is a medicine used to treat depression.

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desvenlafaxine

Pristiq

Pristiq is a medicine used to treat depression in adults.

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deutetrabenazine

Austedo

Austedo and Austedo XR help control movements in adults with Huntington's disease or tardive dyskinesia.

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dexmethylphenidate

Focalin, Focalin XR

AZSTARYS is a stimulant medicine used to treat ADHD.

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diazepam

Valium

Diazepam (Valium) is a medicine that can help with anxiety, muscle spasms, and seizures.

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disulfiram

Antabuse

Disulfiram is a medicine that helps people with long-term alcohol problems stay sober.

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donepezil

Aricept

Donepezil is a medicine used to treat dementia caused by Alzheimer's disease.

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doxepin

Sinequan, Silenor

Doxepin is a medicine that can help you stay asleep.

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duloxetine

Cymbalta

Duloxetine is a medicine that can help treat depression and anxiety.

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entacapone

Comtan

Entacapone is a medicine that helps people with Parkinson's disease.

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escitalopram

Lexapro

Escitalopram is a medicine used to treat depression and anxiety.

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esketamine

Spravato

Spravato is a nasal spray medicine used to treat depression.

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fluoxetine

Prozac, Sarafem

Fluoxetine is a medicine that can help treat depression and other mental health conditions.

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fluphenazine

Prolixin

Fluphenazine (Prolixin) is a medicine used to treat psychotic disorders.

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fluvoxamine

Luvox

Fluvoxamine is a medicine that can help treat obsessive compulsive disorder (OCD).

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galantamine

Razadyne

Galantamine extended-release capsules help treat mild to moderate Alzheimer's disease.

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guanfacine

Intuniv, Tenex

Guanfacine extended-release tablets can help treat ADHD.

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haloperidol

Haldol

Haloperidol is a medicine used to treat mental disorders.

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iloperidone

Fanapt

Fanapt is a medicine used to treat schizophrenia and bipolar disorder.

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imipramine

Tofranil

Imipramine (Tofranil) is a medicine used to treat depression and bedwetting in children.

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levomilnacipran

Fetzima

Fetzima is a medicine used to treat major depressive disorder (MDD) in adults.

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lisdexamfetamine

Vyvanse

Lisdexamfetamine (Vyvanse) is a stimulant medicine.

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lithium

Lithobid, Eskalith

Lithium is a mood stabilizer medicine.

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lorazepam

Ativan

Lorazepam is a medicine that can help with anxiety.

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lurasidone

Latuda

Lurasidone (Latuda) is a medicine used to treat schizophrenia and bipolar depression.

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memantine

Namenda

Memantine is a medicine used to treat moderate to severe Alzheimer's disease.

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methadone

Dolophine

Methadone Hydrochloride Injection is a strong pain medicine.

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methylphenidate

Ritalin, Concerta

Methylphenidate extended-release capsules are a stimulant medicine.

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midazolam

Versed

Midazolam is a medicine that makes you feel calm, relaxed, and sleepy.

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mirtazapine

Remeron

Mirtazapine is a medicine used to treat depression in adults.

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naltrexone

Vivitrol, ReVia

Naltrexone is a medicine that can help treat alcohol and opioid dependence.

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nortriptyline

Pamelor

Nortriptyline (Pamelor) is a medicine used to treat depression.

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olanzapine

Zyprexa

Olanzapine is a medicine used to treat certain mental disorders.

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oxcarbazepine

Trileptal

Oxcarbazepine is a medicine used to treat seizures.

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paliperidone

Invega

Paliperidone extended-release tablets, also known as Invega, are a type of antipsychotic medicine.

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paroxetine

Paxil

Paroxetine (Paxil) is a medicine that can help treat depression and anxiety disorders.

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perphenazine

Trilafon

Perphenazine is a medicine used to treat schizophrenia and control severe nausea and vomiting.

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phenelzine

Nardil

Phenelzine (Nardil) is a medicine used to treat depression.

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pimozide

Orap

Pimozide (Orap) is a medicine that helps control tics in people with Tourette's Disorder.

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pramipexole

Mirapex

Pramipexole extended-release tablets help treat Parkinson's disease.

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protriptyline

Vivactil

Protriptyline (Vivactil) is a medicine used to treat depression.

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quetiapine

Seroquel

Quetiapine is a medicine that belongs to a class of drugs called atypical antipsychotics.

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rasagiline

Azilect

Rasagiline (Azilect) is a medicine used to treat Parkinson's disease.

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risperidone

Risperdal

Risperidone is a medicine used to treat certain mental disorders.

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rivastigmine

Exelon

Rivastigmine (Exelon) is a medicine that helps improve memory and thinking in people with dementia.

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ropinirole

Requip

Ropinirole is a medicine that acts like dopamine in your brain.

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safinamide

Xadago

Safinamide (Xadago) is a drug used with levodopa/carbidopa to treat Parkinson's disease.

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selegiline

Emsam

Selegiline is a medicine that can help manage Parkinson's disease.

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sertraline

Zoloft

Sertraline is a medicine used to treat depression and other mental health conditions.

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tetrabenazine

Xenazine

Tetrabenazine is a medicine used to treat chorea (uncontrollable movements) caused by Huntington's disease.

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thioridazine

Mellaril

Thioridazine is a medicine used to treat schizophrenia.

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tranylcypromine

Parnate

Tranylcypromine (Parnate) is a medicine used to treat major depression in adults.

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trazodone

Desyrel

Trazodone is a medicine used to treat depression.

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valbenazine

Ingrezza

Ingrezza and Ingrezza Sprinkle are medicines used to treat movement problems.

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varenicline

Chantix

Varenicline (Chantix) is a medicine that can help you stop smoking.

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venlafaxine

Effexor, Effexor XR

Venlafaxine is a medication used to treat depression.

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vilazodone

Viibryd

Vilazodone (Viibryd) is a medicine used to treat depression in adults.

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vortioxetine

Trintellix

Trintellix is a medicine used to treat major depressive disorder (MDD) in adults.

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ziprasidone

Geodon

Ziprasidone is a medicine used to treat mental disorders.

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Compare acamprosate vs alprazolam side-by-side →

Mental Health · large class with 5 active shortages

Mental Health is inventory #1 of 22 (77 drugs) ≠ FAERS-volume #2. Nationally Mental Health is inventory #1 of 22 (77 drugs) ≠ Pain Relief FAERS-volume #1 at inventory #3. 77 medicines tracked; 68 carry a NADAC generic flag; 5 in active FDA shortage.

Classes nearest Mental Health by inventory size