Prescription medication · Tetracycline Antibiotic
eravacycline
Also sold as Xerava. Xerava treats complicated infections inside your belly (intra-abdominal).
Data updated 2026-05-15
- 205
- FDA reportsRarely reported
- Rx
- Availability
eravacycline (Xerava) is a prescription Tetracycline Antibiotic. Xerava treats complicated infections inside your belly (intra-abdominal).
Xerava is an antibiotic medicine. It is used to treat complicated infections in the stomach area.
Verify with FDA → · CMS NADAC pricing →
What it does
Xerava treats complicated infections inside your belly (intra-abdominal).
Common side effects
Reactions where the IV goes into your body, Feeling sick to your stomach (nausea), Throwing up
Key warnings
Xerava can cause serious allergic reactions.
The sections below are summarized in plain English from eravacycline's FDA-approved prescribing information. They describe what the official label says, and are not personal medical advice.
How It Works
Xerava is a tetracycline antibiotic. It stops bacteria from growing. This helps your body fight off the infection.
Side Effects (from patient reports)
Based on 205 FDA adverse event reports.
Most-reported reactions
Adverse reactions in FAERS for eravacycline, by number of reports
- Blood Fibrinogen Decreased
Blood Fibrinogen Decreased
16 reports
- Nausea
Nausea
15 reports
- Thrombocytopenia
Thrombocytopenia
14 reports
- Multiple Organ Dysfunction Syndrome
Multiple Organ Dysfunction Syndrome
13 reports
- Lactic Acidosis
Lactic Acidosis
11 reports
- Hypertransaminasaemia
Hypertransaminasaemia
10 reports
- Diarrhoea
Diarrhoea
9 reports
- Pancreatitis
Pancreatitis
8 reports
- Acute Respiratory Distress Syndrome 6
Acute Respiratory Distress Syndrome
6 reports
- Condition Aggravated 6
Condition Aggravated
6 reports
What this shows Bars show how often each reaction was reported, not how likely it is to happen, a report records a temporal association, never proof that the drug caused it.
Reports over time
Adverse-event reports filed for eravacycline each year to the FDA Adverse Event Reporting System (FAERS).
Year-to-year volume tracks usage, prescribing, and scrutiny, not a change in per-patient risk. Source: FDA FAERS.
Where eravacycline sits
eravacycline has more FDA adverse-event reports than 2% of the drugs FAERS tracks. A high position reflects how widely a drug is used and watched, not how dangerous it is.
Percentile across all drugs PlainMeds tracks by FAERS report volume. The dot is eravacycline; the line is the median (50th percentile).
FDA Adverse Event Report Analysis
Detailed analysis of 205 reports from the FDA Adverse Event Reporting System (FAERS). Reports span 2019–2025.
Total Reports
205
Reports Mentioning Death
33
16.1% of reports — not proof of cause
Hospitalization Reports
57
Top Indication
Product Used For Unknown Indication
Gender Distribution
Age Distribution
Most Reported Adverse Reactions (FAERS)
| # | Reaction | Reports |
|---|---|---|
| 3 | BLOOD FIBRINOGEN DECREASED | 16 |
| 4 | NAUSEA | 15 |
| 5 | THROMBOCYTOPENIA | 14 |
| 6 | MULTIPLE ORGAN DYSFUNCTION SYNDROME | 13 |
| 8 | LACTIC ACIDOSIS | 11 |
| 9 | HYPERTRANSAMINASAEMIA | 10 |
| 10 | DIARRHOEA | 9 |
| 11 | PANCREATITIS | 8 |
| 12 | ACUTE RESPIRATORY DISTRESS SYNDROME | 6 |
| 13 | CONDITION AGGRAVATED | 6 |
| 15 | ENTEROCOCCAL INFECTION | 6 |
| 16 | PROTHROMBIN TIME PROLONGED | 6 |
| 17 | SEPSIS | 6 |
| 18 | BLOOD BILIRUBIN INCREASED | 5 |
| 19 | DRUG INEFFECTIVE FOR UNAPPROVED INDICATION | 5 |
Reactions in Death Reports
Reactions in Hospitalization Reports
Source: FDA FAERS (Adverse Event Reporting System) Reports are voluntary and do not establish causation
Serious Warnings
Xerava can cause serious allergic reactions. If you are allergic to tetracycline antibiotics, you should not take Xerava. Using Xerava while teeth are developing can cause tooth discoloration. It can also slow bone growth in babies and children under 8.
Common Questions
What if I'm allergic to tetracyclines?
Can Xerava affect my teeth?
Can Xerava affect bone growth?
What should I do if I get diarrhea while taking Xerava?
Can I breastfeed while taking Xerava?
What if I am taking a blood thinner?
What if I am taking medicine that affects liver enzymes?
How long will I need to take Xerava?
How is Xerava given?
What does Xerava look like?
What are the common side effects of eravacycline?
What drug class is eravacycline?
What pregnancy or breastfeeding source fields are listed for eravacycline?
Related Medications in Tetracycline Antibiotic
Other drugs grouped near eravacycline - same-class peers and common alternatives.
amikacin
Amikin
Amikacin is an antibiotic medicine.
Compare with eravacycline →
amoxicillin
Amoxil
Amoxicillin and Clavulanate Potassium is a combination medicine used to fight bacterial infections.
Compare with eravacycline →
amoxicillin/clavulanate
Augmentin
Augmentin is a combination of two medicines, amoxicillin and clavulanate.
Compare with eravacycline →
ampicillin/sulbactam
Unasyn
Unasyn is a combination of two antibiotics that fights bacteria in your body.
Compare with eravacycline →
azithromycin
Zithromax, Z-Pack
Azithromycin is an antibiotic that fights bacteria.
Compare with eravacycline →
Compare beyond drug class
Nationwide peers by FAERS volume & death-report share
Two PlainMeds-derived comparison paths for eravacycline: nearest FDA FAERS report volume and nearest death-report share among drugs with at least 1,000 logged reports, excluding same-class neighbors listed above. Counts reflect reporting volume, not proven individual harm.
Similar FAERS report volume
Nearest drugs by total FAERS reports. This record: 205.
Similar death-report share
Nearest drugs by FAERS death-report share. This record: 16.10%.
- prednisolone Δ 0.03 pts · 173,227 reports · Corticosteroid 16.07%death share
- donepezil Δ 0.10 pts · 35,138 reports · Acetylcholinesterase Inhibitor 16.00%death share
- dexamethasone Δ 0.11 pts · 285,895 reports · Corticosteroid 16.20%death share
- bumetanide Δ 0.12 pts · 25,027 reports · Loop Diuretic 15.98%death share
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Common Drug Interactions
Dangerous medication combinations and how to protect yourself
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What the FDA Data Shows for eravacycline
The FDA label for eravacycline (sold under brand names such as Xerava) classifies it as a prescription-only medication in the Tetracycline Antibiotic class. Xerava treats complicated infections inside your belly (intra-abdominal). Official labeling lists 3 commonly reported side effects, including Reactions where the IV goes into your body, Feeling sick to your stomach (nausea), Throwing up.
Post-market surveillance from the FDA Adverse Event Reporting System (FAERS) captures real-world experience. For this drug, FAERS contains 205 voluntary reports. Interaction data is drawn directly from FDA-approved prescribing information. Acquisition-cost data is surveyed weekly by CMS and updated as manufacturers report changes.
Report counts do not establish causation, a FAERS entry documents a temporal association, not proof that the drug produced the outcome. Widely prescribed medications naturally accumulate more reports than niche therapies, so raw totals must be interpreted alongside total exposure. Shortage status, recall history, and patent information are separate source-record fields. This page is a public FDA/CMS registry and does not provide medical, treatment, substitution, or medication-change directions.
Data Sources
Drug labeling: FDA Drug Labels (SPL/DailyMed). Adverse events: FDA Adverse Event Reporting System (FAERS).
FAERS reports are voluntary and do not establish causation. Drug interactions are derived from FDA labeling and clinical references. This registry does not provide medication decisions.
Last updated: September 22, 2025
PlainMeds is rendered directly from FDA openFDA/FAERS extracts, DailyMed labels, and CMS drug-pricing files, no number is typed in by an editor. FAERS counts, recalls, shortages, and price figures on this page are queried live from those federal extracts. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error. Data current as of 2026-05-15. Primary sources: openFDA / FAERS, DailyMed and CMS Part B ASP.
Read our methodology - how this data is sourced, computed, and verified.
Data currency: FDA FAERS adverse-event reports through 2025, CMS NADAC acquisition-cost pricing effective December 2024, compiled from the source snapshot dated . See our methodology for per-source dates and refresh cadence. Spot a figure that looks wrong? Report a data issue.
All federal data sources used on this page
- FDA Orange Book - approved drug products with therapeutic equivalence. accessdata.fda.gov/cder/ob
- FDA DailyMed - NIH-hosted drug labeling for FDA-approved meds. dailymed.nlm.nih.gov
- FDA Adverse Event Reporting System (FAERS) - post-marketing safety surveillance. fda.gov/drugs/faers
- NLM RxNorm - standardized clinical drug nomenclature. nlm.nih.gov/research/umls/rxnorm
- CMS Medicare Part B Drug Average Sales Price Files - federal drug pricing data. cms.gov/medicare/part-b-drugs/asp
- FDA Drug Shortages Database - current and resolved drug shortage tracking. accessdata.fda.gov/drugshortages