Medication class
Infections
Antiviral and antifungal medications for treating viral infections like herpes and HIV, and fungal infections.
Data updated 2026-05-15
- 41
- Medications
- 25
- With a generic
- 92%
- Avg generic savings
- 0
- In active shortage
Drug class assignments follow the FDA openFDA therapeutic classification, and clinical details are drawn from FDA Structured Product Labeling (DailyMed). See the full sources below.
PlainMeds tracks 41 infections medications compiled from official FDA drug labels, including acyclovir, fluconazole, doxycycline hyclate.
Infections medications are grouped here by the openFDA therapeutic classification and drawn from FDA Structured Product Labeling. PlainMeds lists 41 in this class, 25 with a lower-cost generic available (averaging about 92% versus brand). Each drug page covers labeled uses, FAERS-reported side effects, interactions, recalls and NADAC pricing. This is educational information from public data, not medical advice.
What infections drugs cost
Highest NADAC acquisition cost per unit in this class, brand and generic
- sofosbuvir/velpatasvir
sofosbuvir/velpatasvir
$863 per unit
- mebendazole
mebendazole
$650 per unit
- baloxavir marboxil $157
baloxavir marboxil
$157 per unit
- glecaprevir/pibrentasvir $153
glecaprevir/pibrentasvir
$153 per unit
- bictegravir/emtricitabine/tenofovir $129
bictegravir/emtricitabine/tenofovir
$129 per unit
- isavuconazonium $108
isavuconazonium
$108 per unit
- dolutegravir/lamivudine $96
dolutegravir/lamivudine
$96 per unit
- dolutegravir $73
dolutegravir
$73 per unit
- emtricitabine/tenofovir $71
emtricitabine/tenofovir
$71 per unit
- nirmatrelvir/ritonavir $70
nirmatrelvir/ritonavir
$70 per unit
What this shows sofosbuvir/velpatasvir is the costliest in this class at $863.00/unit; generics in the same class run a fraction of that.
Generic availability vs other classes
61% of infections medications have a generic available, ranking #19 of 22 therapeutic classes (the typical class sits near 74%).
Source: CMS NADAC generic-availability flags across all PlainMeds therapeutic classes. The dot is this class; the line is the cross-class median.
acyclovir
Zovirax
Acyclovir is an antiviral medicine.
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albendazole
Albenza
Albendazole is a medicine that fights parasites.
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amphotericin B
Ambisome, Fungizone
Amphotericin B liposome is an antifungal medicine.
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anidulafungin
Eraxis
Eraxis is an antifungal medicine.
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atovaquone/proguanil
Malarone
Malarone is a drug used to prevent and treat malaria.
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baloxavir marboxil
Xofluza
Xofluza is an antiviral medicine that can treat the flu.
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bictegravir/emtricitabine/tenofovir
Biktarvy
Biktarvy is a complete HIV-1 treatment for adults and children who weigh at least 31 pounds.
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caspofungin
Cancidas
Caspofungin is an antifungal medicine.
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chloroquine
Aralen
Chloroquine phosphate is a drug used to treat and prevent malaria.
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cidofovir
Vistide
Cidofovir injection is an antiviral medicine.
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darunavir
Prezista
Darunavir is a medicine used to treat HIV.
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dolutegravir
Tivicay
TRIUMEQ is a drug that contains three medicines in one pill: dolutegravir, abacavir, and lamivudine.
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dolutegravir/lamivudine
Dovato
Dovato is a complete HIV-1 treatment that combines two medicines into one tablet.
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doxycycline hyclate
Doryx MPC
Doxycycline hyclate is an antibiotic that fights bacteria in your body.
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efavirenz/emtricitabine/tenofovir
Atripla
Efavirenz is a drug used to treat HIV-1 infection.
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emtricitabine/tenofovir
Truvada, Descovy
Truvada is a medicine that contains two drugs, emtricitabine and tenofovir.
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entecavir
Baraclude
Entecavir is a medicine used to treat chronic hepatitis B infection.
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famciclovir
Famvir
Famciclovir is an antiviral medicine.
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fluconazole
Diflucan
Fluconazole is an antifungal medicine.
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ganciclovir
Cytovene
Ganciclovir injection is an antiviral medicine.
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glecaprevir/pibrentasvir
Mavyret
Mavyret is a medicine used to treat hepatitis C (HCV) in adults and children 3 years and older.
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griseofulvin
Grifulvin V
Griseofulvin is an antifungal medicine.
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isavuconazonium
Cresemba
Cresemba is an antifungal medicine.
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itraconazole
Sporanox
Itraconazole capsules are an antifungal medicine.
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ivermectin
Stromectol
Ivermectin is a medicine used to treat infections caused by certain parasitic worms.
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ledipasvir/sofosbuvir
Harvoni
Harvoni is a medicine that contains ledipasvir and sofosbuvir.
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mebendazole
Emverm
Emverm is a medicine used to treat worm infections in your gut.
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micafungin
Mycamine
Micafungin is an antifungal medicine.
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molnupiravir
Lagevrio
Lagevrio contains molnupiravir, an antiviral medicine.
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nirmatrelvir/ritonavir
Paxlovid
Paxlovid is a medicine used to treat mild to moderate COVID-19 in adults.
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nystatin
Mycostatin
Nystatin topical powder is an antifungal medicine.
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oseltamivir
Tamiflu
Oseltamivir (Tamiflu) is an antiviral medicine.
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posaconazole
Noxafil
Posaconazole is an antifungal medicine.
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remdesivir
Veklury
Remdesivir (Veklury) is an antiviral medicine used to treat COVID-19.
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sofosbuvir/velpatasvir
Epclusa
Vosevi is a drug that combines three medicines into one tablet.
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tecovirimat
Tpoxx
Tpoxx is an antiviral medicine used to treat smallpox.
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tenofovir disoproxil
Viread
Tenofovir disoproxil fumarate is a medicine used to treat HIV and hepatitis B.
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terbinafine
Lamisil
Terbinafine is an antifungal medicine.
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valacyclovir
Valtrex
Valacyclovir is an antiviral medicine.
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valganciclovir
Valcyte
Valganciclovir is an antiviral medicine.
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voriconazole
Vfend
Voriconazole (Vfend) is an antifungal medicine.
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Understanding the Infections Category
The Infections category currently lists 41 medications in this database, each drawn from FDA drug labels and grouped by therapeutic classification. Antiviral and antifungal medications for treating viral infections like herpes and HIV, and fungal infections. Clinical guidelines usually treat these medications as a reference set when weighing treatment options, switching strategies, or comparing safety profiles.
Within this category you'll find examples such as acyclovir, fluconazole, doxycycline hyclate, alongside 38 other entries. Each drug page links to the same underlying FDA data, labeled uses, adverse events reported to FAERS, documented interactions, warnings, and, where available, NADAC acquisition pricing from CMS. Over-the-counter and prescription options can sit in the same category but follow different regulatory pathways: OTC products have simplified labeling aimed at self-care, while prescription drugs include detailed monographs meant for clinicians. That distinction matters when comparing dosing, monitoring requirements, and contraindications.
Browsing a category is a research starting point, not a treatment recommendation. Effectiveness, tolerability, and cost for any individual patient depend on the specific condition, comorbidities, other medications, genetics, and insurance coverage, none of which can be inferred from a category list alone. FAERS report counts, recall history, and shortage status all evolve as new data is reported to the FDA, so the relative standing of drugs in this class can shift month to month. This page is for educational purposes only and is not medical advice, a licensed clinician is the right source for personalized guidance.
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Read our methodology - how this data is sourced, computed, and verified.
Data currency: FDA FAERS adverse-event reports through 2025, CMS NADAC acquisition-cost pricing effective December 2024, compiled and last refreshed May 2026. See our methodology for per-source dates and refresh cadence. Spot a figure that looks wrong? Report a correction.