Medication class
Seizures & Nerve Pain
Anticonvulsant and antiepileptic medications also used for nerve pain, including gabapentin, pregabalin, and carbamazepine.
Data updated 2026-05-15
- 23
- Medications
- 21
- With a generic
- 91%
- Avg generic savings
- 2
- In active shortage
Drug class assignments follow the FDA openFDA therapeutic classification, and clinical details are drawn from FDA Structured Product Labeling (DailyMed). See the full sources below.
PlainMeds tracks 23 seizures & nerve pain medications compiled from official FDA drug labels, including gabapentin, pregabalin, clonazepam.
Seizures & Nerve Pain medications are grouped here by the openFDA therapeutic classification and drawn from FDA Structured Product Labeling. PlainMeds lists 23 in this class, 21 with a lower-cost generic available (averaging about 91% versus brand). Each drug page covers labeled uses, FAERS-reported side effects, interactions, recalls and NADAC pricing. This is educational information from public data, not medical advice.
What seizures & nerve pain drugs cost
Highest NADAC acquisition cost per unit in this class, brand and generic
- primidone
primidone
$63 per unit
- cenobamate
cenobamate
$38 per unit
- clobazam
clobazam
$29 per unit
- brivaracetam $23
brivaracetam
$23 per unit
- levetiracetam $19
levetiracetam
$19 per unit
- topiramate $17
topiramate
$17 per unit
- felbamate $14
felbamate
$14 per unit
- rufinamide $13
rufinamide
$13 per unit
- lamotrigine $11
lamotrigine
$11 per unit
- pregabalin $10
pregabalin
$10 per unit
What this shows primidone is the costliest in this class at $63.00/unit; generics in the same class run a fraction of that.
Generic availability vs other classes
91% of seizures & nerve pain medications have a generic available, ranking #2 of 22 therapeutic classes (the typical class sits near 74%).
Source: CMS NADAC generic-availability flags across all PlainMeds therapeutic classes. The dot is this class; the line is the cross-class median.
brivaracetam
Briviact
Brivaracetam is a medicine used to treat partial-onset seizures.
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cannabidiol
Epidiolex
Epidiolex is a medicine that contains cannabidiol.
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carbamazepine
Tegretol
Carbamazepine is a medicine used to control seizures and treat nerve pain.
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cenobamate
Xcopri
Xcopri is a medicine used to treat partial-onset seizures in adults.
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clobazam
Onfi, Sympazan
Clobazam oral suspension is a medicine used with other medicines to treat seizures caused by Lennox-Gastaut syndrome.
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clonazepam
Klonopin
Clonazepam is a medicine that belongs to the benzodiazepine class.
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ethosuximide
Zarontin
Ethosuximide is a medicine that helps control absence seizures.
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felbamate
Felbatol
Felbamate is a medicine used to treat seizures.
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gabapentin
Neurontin, Gralise
Gabapentin is a medicine that can treat nerve pain and seizures.
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lacosamide
Vimpat
Lacosamide is a medicine that can help control seizures.
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lamotrigine
Lamictal
Lamotrigine is a medicine that can treat seizures and bipolar disorder.
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levetiracetam
Keppra
Levetiracetam is a medicine used to treat seizures.
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perampanel
Fycompa
Perampanel is a medicine used to treat seizures.
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phenobarbital
Luminal
Phenobarbital is a medicine that can help control seizures and calm you down.
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phenytoin
Dilantin
Phenytoin injection is used to treat certain types of seizures.
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pregabalin
Lyrica
Pregabalin (Lyrica) is a medicine that can help manage nerve pain, fibromyalgia, and partial-onset seizures.
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primidone
Mysoline
Primidone is a medicine used to control seizures.
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rufinamide
Banzel
Banzel is a medicine used with other medicines to treat seizures.
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tiagabine
Gabitril
Tiagabine is a medicine used with other medicines to treat partial seizures.
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topiramate
Topamax
Topiramate is a medicine that can help prevent seizures and migraines.
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valproate
Depakote, Depakene
Valproate sodium injection is used when you cannot take valproate pills.
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vigabatrin
Sabril
Vigabatrin (Sabril) is a medicine used to treat certain types of seizures in adults and children.
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zonisamide
Zonegran
Zonisamide is a medicine used with other medicines to treat partial seizures in adults with epilepsy.
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Understanding the Seizures & Nerve Pain Category
The Seizures & Nerve Pain category currently lists 23 medications in this database, each drawn from FDA drug labels and grouped by therapeutic classification. Anticonvulsant and antiepileptic medications also used for nerve pain, including gabapentin, pregabalin, and carbamazepine. Clinical guidelines usually treat these medications as a reference set when weighing treatment options, switching strategies, or comparing safety profiles.
Within this category you'll find examples such as gabapentin, pregabalin, clonazepam, alongside 20 other entries. Each drug page links to the same underlying FDA data, labeled uses, adverse events reported to FAERS, documented interactions, warnings, and, where available, NADAC acquisition pricing from CMS. Over-the-counter and prescription options can sit in the same category but follow different regulatory pathways: OTC products have simplified labeling aimed at self-care, while prescription drugs include detailed monographs meant for clinicians. That distinction matters when comparing dosing, monitoring requirements, and contraindications.
Browsing a category is a research starting point, not a treatment recommendation. Effectiveness, tolerability, and cost for any individual patient depend on the specific condition, comorbidities, other medications, genetics, and insurance coverage, none of which can be inferred from a category list alone. FAERS report counts, recall history, and shortage status all evolve as new data is reported to the FDA, so the relative standing of drugs in this class can shift month to month. This page is for educational purposes only and is not medical advice, a licensed clinician is the right source for personalized guidance.
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Read our methodology - how this data is sourced, computed, and verified.
Data currency: FDA FAERS adverse-event reports through 2025, CMS NADAC acquisition-cost pricing effective December 2024, compiled and last refreshed May 2026. See our methodology for per-source dates and refresh cadence. Spot a figure that looks wrong? Report a correction.