Medication class
Blood Pressure
Medications used to treat high blood pressure (hypertension), including ACE inhibitors, ARBs, calcium channel blockers, and beta-blockers.
Data updated 2026-05-15
- 54
- Medications
- 46
- With a generic
- 96%
- Avg generic savings
- 2
- In active shortage
Drug class assignments follow the FDA openFDA therapeutic classification, and clinical details are drawn from FDA Structured Product Labeling (DailyMed). See the full sources below.
PlainMeds tracks 54 blood pressure medications compiled from official FDA drug labels, including lisinopril, amlodipine, metoprolol.
Blood Pressure medications are grouped here by the openFDA therapeutic classification and drawn from FDA Structured Product Labeling. PlainMeds lists 54 in this class, 46 with a lower-cost generic available (averaging about 96% versus brand). Each drug page covers labeled uses, FAERS-reported side effects, interactions, recalls and NADAC pricing. This is educational information from public data, not medical advice.
What blood pressure drugs cost
Highest NADAC acquisition cost per unit in this class, brand and generic
- olmesartan/amlodipine/hydrochlorothiazide
olmesartan/amlodipine/hydrochlorothiazide
$16 per unit
- eplerenone
eplerenone
$14 per unit
- atenolol
atenolol
$13 per unit
- aliskiren
aliskiren
$13 per unit
- lisinopril
lisinopril
$13 per unit
- amlodipine/benazepril
amlodipine/benazepril
$12 per unit
- amlodipine/valsartan
amlodipine/valsartan
$11 per unit
- amlodipine
amlodipine
$11 per unit
- olmesartan
olmesartan
$10 per unit
- valsartan
valsartan
$10 per unit
What this shows olmesartan/amlodipine/hydrochlorothiazide is the costliest in this class at $16.00/unit; generics in the same class run a fraction of that.
Generic availability vs other classes
85% of blood pressure medications have a generic available, ranking #7 of 22 therapeutic classes (the typical class sits near 74%).
Source: CMS NADAC generic-availability flags across all PlainMeds therapeutic classes. The dot is this class; the line is the cross-class median.
acebutolol
Sectral
Acebutolol is a medicine that helps lower blood pressure and control irregular heartbeats.
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aliskiren
Tekturna
Tekturna is a medicine used to treat high blood pressure.
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amiloride
Midamor
Amiloride is a water pill that helps your body hold onto potassium.
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amlodipine
Norvasc
Amlodipine (Norvasc) is a drug that lowers blood pressure and treats chest pain.
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amlodipine/benazepril
Lotrel
Lotrel is a combination medicine that contains amlodipine and benazepril.
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amlodipine/valsartan
Exforge
Exforge HCT is a combination medicine used to treat high blood pressure.
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atenolol
Tenormin
Atenolol is a medicine that lowers blood pressure.
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azilsartan
Edarbi
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benazepril
Lotensin
Benazepril (Lotensin) is a medicine that lowers your blood pressure.
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bisoprolol
Zebeta
Bisoprolol (Zebeta) is a medicine that lowers high blood pressure.
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candesartan
Atacand
Candesartan is a medicine that lowers blood pressure.
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chlorthalidone
Thalitone
Chlorthalidone is a water pill that helps lower blood pressure and reduce swelling.
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clonidine
Catapres
Clonidine (Catapres) is a medicine used to treat high blood pressure.
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diltiazem
Cardizem, Tiazac
Diltiazem is a medicine that helps lower high blood pressure and prevent chest pain.
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doxazosin
Cardura
Doxazosin is a medicine that can help lower high blood pressure and improve symptoms of an enlarged prostate in men.
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enalapril
Vasotec
Enalapril (Vasotec) is a medicine that lowers blood pressure and helps treat heart failure.
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eplerenone
Inspra
Eplerenone (Inspra) helps you live longer if you have heart failure after a heart attack.
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eprosartan
Teveten
Eprosartan (Teveten) is a medicine that lowers high blood pressure.
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felodipine
Plendil
Felodipine is a drug that lowers your blood pressure.
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fosinopril
Monopril
Fosinopril is a medicine that lowers blood pressure.
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hydralazine
Apresoline
Hydralazine is a drug that lowers blood pressure by relaxing blood vessels.
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hydrochlorothiazide
Microzide
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hydrochlorothiazide/lisinopril
Zestoretic
Zestoretic is a drug that combines lisinopril and hydrochlorothiazide.
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hydrochlorothiazide/losartan
Hyzaar
Hyzaar is a combination medicine that contains losartan and hydrochlorothiazide.
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hydrochlorothiazide/triamterene
Dyazide, Maxzide
This medicine combines lisinopril and hydrochlorothiazide to lower high blood pressure.
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indapamide
Lozol
Indapamide is a water pill that helps lower blood pressure and reduce fluid buildup in the body.
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irbesartan
Avapro
Irbesartan is a medicine that lowers blood pressure.
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isradipine
DynaCirc
Isradipine is a drug that helps lower high blood pressure.
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labetalol
Trandate
Labetalol is a medicine that lowers high blood pressure.
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lisinopril
Prinivil, Zestril
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losartan
Cozaar
Losartan is a medicine that lowers blood pressure.
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methyldopa
Aldomet
Methyldopa is a medicine used to treat high blood pressure.
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metolazone
Zaroxolyn
Metolazone is a water pill that helps your body get rid of extra salt and water.
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metoprolol
Lopressor, Toprol-XL
Metoprolol is a beta-blocker medicine.
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minoxidil
Loniten
Minoxidil (Loniten) is a medicine that helps regrow hair.
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moexipril
Univasc
Moexipril is a medicine used to treat high blood pressure.
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nadolol
Corgard
Nadolol is a medicine that helps lower blood pressure and manage chest pain (angina).
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nebivolol
Bystolic
Nebivolol is a medicine that lowers high blood pressure.
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nicardipine
Cardene
Nicardipine is a drug that helps to lower blood pressure and treat chest pain.
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nifedipine
Procardia, Adalat
Nifedipine is a calcium channel blocker.
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nisoldipine
Sular
Nisoldipine is a medicine to treat high blood pressure.
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olmesartan
Benicar
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olmesartan/amlodipine/hydrochlorothiazide
Tribenzor
Tribenzor is a drug that combines three medicines to lower high blood pressure.
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perindopril
Aceon
Perindopril (Aceon) is a drug that lowers blood pressure.
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pindolol
Visken
Pindolol is a medicine that lowers high blood pressure.
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prazosin
Minipress
Prazosin (Minipress) is a medicine that lowers your blood pressure.
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propranolol
Inderal
Propranolol is a medicine that can help with high blood pressure, chest pain, and other conditions.
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quinapril
Accupril
Quinapril is a medicine that lowers blood pressure.
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ramipril
Altace
Ramipril is a medicine that lowers blood pressure.
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telmisartan
Micardis
Telmisartan (Micardis) is a medicine that lowers blood pressure.
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terazosin
Hytrin
Terazosin is a medicine that can help men with enlarged prostate and also treat high blood pressure.
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trandolapril
Mavik
Trandolapril (Mavik) is a medicine that lowers blood pressure.
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valsartan
Diovan
Entresto is a medicine that combines two drugs to help adults and children with heart failure.
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verapamil
Calan, Verelan
Verapamil is a drug that helps to lower blood pressure and treat chest pain (angina) and irregular heartbeats (arrhythmias).
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Understanding the Blood Pressure Category
The Blood Pressure category currently lists 54 medications in this database, each drawn from FDA drug labels and grouped by therapeutic classification. Medications used to treat high blood pressure (hypertension), including ACE inhibitors, ARBs, calcium channel blockers, and beta-blockers. Clinical guidelines usually treat these medications as a reference set when weighing treatment options, switching strategies, or comparing safety profiles.
Within this category you'll find examples such as lisinopril, amlodipine, metoprolol, alongside 51 other entries. Each drug page links to the same underlying FDA data, labeled uses, adverse events reported to FAERS, documented interactions, warnings, and, where available, NADAC acquisition pricing from CMS. Over-the-counter and prescription options can sit in the same category but follow different regulatory pathways: OTC products have simplified labeling aimed at self-care, while prescription drugs include detailed monographs meant for clinicians. That distinction matters when comparing dosing, monitoring requirements, and contraindications.
Browsing a category is a research starting point, not a treatment recommendation. Effectiveness, tolerability, and cost for any individual patient depend on the specific condition, comorbidities, other medications, genetics, and insurance coverage, none of which can be inferred from a category list alone. FAERS report counts, recall history, and shortage status all evolve as new data is reported to the FDA, so the relative standing of drugs in this class can shift month to month. This page is for educational purposes only and is not medical advice, a licensed clinician is the right source for personalized guidance.
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Read our methodology - how this data is sourced, computed, and verified.
Data currency: FDA FAERS adverse-event reports through 2025, CMS NADAC acquisition-cost pricing effective December 2024, compiled and last refreshed May 2026. See our methodology for per-source dates and refresh cadence. Spot a figure that looks wrong? Report a correction.