PlainMeds provides educational information only. This is not medical advice. Always consult your doctor or pharmacist.

Medication class

Heart

Drugs for heart failure, arrhythmias, angina, and other cardiovascular conditions beyond blood pressure management.

Data updated 2026-05-15

31
Medications
27
With a generic
85%
Avg generic savings
6
In active shortage

Drug class assignments follow the FDA openFDA therapeutic classification, and clinical details are drawn from FDA Structured Product Labeling (DailyMed). See the full sources below.

PlainMeds tracks 31 heart medications compiled from official FDA drug labels, including furosemide, spironolactone, carvedilol.

Heart medications are grouped here by the openFDA therapeutic classification and drawn from FDA Structured Product Labeling. PlainMeds lists 31 in this class, 27 with a lower-cost generic available (averaging about 85% versus brand). Each drug page covers labeled uses, FAERS-reported side effects, interactions, recalls and NADAC pricing. This is educational information from public data, not medical advice.

What heart drugs cost

Highest NADAC acquisition cost per unit in this class, brand and generic

per unit

What this shows nitroglycerin is the costliest in this class at $51.00/unit; generics in the same class run a fraction of that.

Source CMS National Average Drug Acquisition Cost (NADAC)

Generic availability vs other classes

87% of heart medications have a generic available, ranking #6 of 22 therapeutic classes (the typical class sits near 74%).

47% (lowest class) 100% (highest class)

Source: CMS NADAC generic-availability flags across all PlainMeds therapeutic classes. The dot is this class; the line is the cross-class median.

adenosine

Adenocard

Adenosine (Adenocard) is a medicine used to treat certain types of irregular heartbeats.

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amiodarone

Cordarone, Pacerone

Amiodarone (Pacerone) is a medicine used to treat life-threatening, irregular heartbeats.

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atropine

AtroPen

Atropine is a medicine that can temporarily block severe effects on your body.

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bumetanide

Bumex

Bumetanide is a water pill (diuretic).

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carvedilol

Coreg

Carvedilol is a medicine that lowers blood pressure and helps your heart work better.

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digoxin

Lanoxin

Digoxin (Lanoxin) is a medicine that helps your heart pump better.

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dobutamine

Dobutrex

Dobutamine is a medicine that helps your heart pump better.

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dofetilide

Tikosyn

Dofetilide (Tikosyn) helps keep your heart in a normal rhythm if you have atrial fibrillation or atrial flutter.

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dopamine

Intropin

Dopamine injection helps improve blood flow in patients suffering from shock.

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dronedarone

Multaq

Multaq is a medicine that helps lower the risk of needing to stay in the hospital for atrial fibrillation (AFib).

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epinephrine

EpiPen, Adrenalin

Epinephrine injection is a medicine that raises blood pressure.

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ethacrynic acid

Edecrin

Ethacrynic acid (Edecrin) is a strong diuretic, also known as a water pill.

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flecainide

Tambocor

Flecainide is a medicine used to prevent irregular heartbeats.

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furosemide

Lasix

Furosemide is a water pill (diuretic).

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hydralazine/isosorbide dinitrate

BiDil

BiDil is a medicine that combines two drugs to help treat heart failure.

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isosorbide dinitrate

Isordil

Isosorbide dinitrate is a medicine that helps prevent chest pain (angina).

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isosorbide mononitrate

Imdur

Isosorbide mononitrate is a medicine that helps prevent chest pain.

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ivabradine

Corlanor

Ivabradine (Corlanor) is a medicine that helps lower the risk of needing to go to the hospital for worsening heart failure.

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mexiletine

Mexitil

Mexiletine is a medicine used to treat life-threatening heart rhythm problems.

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milrinone

Primacor

Milrinone is a medicine used in the hospital for a short time to help people with severe heart failure.

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nitroglycerin

Nitrostat, Nitro-Dur

Nitroglycerin sublingual tablets help to relieve chest pain (angina) due to heart disease.

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norepinephrine

Levophed

Norepinephrine injection raises blood pressure in adults with very low blood pressure.

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phenylephrine

Neo-Synephrine

Phenylephrine is a medicine that helps relieve cold and flu symptoms.

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propafenone

Rythmol

Propafenone (Rythmol) is a medicine that helps control irregular heartbeats.

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ranolazine

Ranexa

Ranolazine extended-release tablets help treat chronic angina (chest pain).

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sacubitril/valsartan

Entresto

Entresto is a medicine that combines two drugs to help adults and children with heart failure.

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sotalol

Betapace

Sotalol is a medicine that helps keep your heart beating regularly.

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spironolactone

Aldactone

Spironolactone is a medicine that helps remove extra fluid from your body and lower blood pressure.

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torsemide

Demadex

Torsemide is a water pill (diuretic).

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vasopressin

Vasostrict

Vasopressin injection helps raise blood pressure in adults with shock.

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vericiguat

Verquvo

Verquvo is a medicine that helps lower the risk of death and hospitalization from heart failure.

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Compare adenosine vs amiodarone side-by-side →

Understanding the Heart Category

The Heart category currently lists 31 medications in this database, each drawn from FDA drug labels and grouped by therapeutic classification. Drugs for heart failure, arrhythmias, angina, and other cardiovascular conditions beyond blood pressure management. Clinical guidelines usually treat these medications as a reference set when weighing treatment options, switching strategies, or comparing safety profiles.

Within this category you'll find examples such as furosemide, spironolactone, carvedilol, alongside 28 other entries. Each drug page links to the same underlying FDA data, labeled uses, adverse events reported to FAERS, documented interactions, warnings, and, where available, NADAC acquisition pricing from CMS. Over-the-counter and prescription options can sit in the same category but follow different regulatory pathways: OTC products have simplified labeling aimed at self-care, while prescription drugs include detailed monographs meant for clinicians. That distinction matters when comparing dosing, monitoring requirements, and contraindications.

Browsing a category is a research starting point, not a treatment recommendation. Effectiveness, tolerability, and cost for any individual patient depend on the specific condition, comorbidities, other medications, genetics, and insurance coverage, none of which can be inferred from a category list alone. FAERS report counts, recall history, and shortage status all evolve as new data is reported to the FDA, so the relative standing of drugs in this class can shift month to month. This page is for educational purposes only and is not medical advice, a licensed clinician is the right source for personalized guidance.

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Sources: FDA Drug Labels (SPL); openFDA therapeutic classification.

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Read our methodology - how this data is sourced, computed, and verified.

Data currency: FDA FAERS adverse-event reports through 2025, CMS NADAC acquisition-cost pricing effective December 2024, compiled and last refreshed May 2026. See our methodology for per-source dates and refresh cadence. Spot a figure that looks wrong? Report a correction.