Medication class
Heart
Drugs for heart failure, arrhythmias, angina, and other cardiovascular conditions beyond blood pressure management.
Data updated 2026-05-15
- 31
- Medications
- 27
- With a generic
- 85%
- Avg generic savings
- 6
- In active shortage
Drug class assignments follow the FDA openFDA therapeutic classification, clinical details are drawn from FDA Structured Product Labeling via DailyMed, and unit-price comparisons use CMS National Average Drug Acquisition Cost data. See the full sources below.
Inventory versus report volume
Heart is inventory #11 of 22 (31 drugs) ≠ FAERS-volume #10. Nationally Mental Health is inventory #1 of 22 (77 drugs) ≠ Pain Relief FAERS-volume #1 at inventory #3.
- #11
- inventory
- 31
- tracked drugs
- #10
- FAERS volume
- #1
- Pain Relief FAERS nationally
According to FDA FAERS report totals and openFDA class inventory compiled on /methodology. Class size is not the same map as report volume. This page is for informational purposes only and is not medical advice.
This class - generic availability cut
Exclusive DISTINCT-drug split of 31 medicines in Heart. Orthogonal to inventory vs FAERS dual and to the NADAC cost ChartBar.
nitroglycerin tops Heart NADAC at $51.00/unit
Top 10 acquisition costs in this class (CMS NADAC)
- nitroglycerin
nitroglycerin
$51 per unit
- vericiguat
vericiguat
$22 per unit
- epinephrine $14
epinephrine
$14 per unit
- dronedarone $13
dronedarone
$13 per unit
- sacubitril/valsartan $11
sacubitril/valsartan
$11 per unit
- dofetilide $11
dofetilide
$11 per unit
- ivabradine $10
ivabradine
$10 per unit
- atropine $6
atropine
$6 per unit
- hydralazine/isosorbide dinitrate $4
hydralazine/isosorbide dinitrate
$4 per unit
- digoxin $1
digoxin
$1 per unit
What this shows nitroglycerin is the costliest in this class at $51.00/unit; generics in the same class run a fraction of that.
Heart · #11 inventory of 22 therapeutic classes
11 classes have fewer tracked drugs; percentile 50 among PlainMeds categories.
Heart vs all classes by tracked-drug count
Where this class's inventory sits among every PlainMeds therapeutic category
31 11th of 22 higher than 11 of 22 classes
Classes, banded by tracked-drug inventory
Each bar is a band; taller bars hold more classes. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source PlainMeds openFDA therapeutic-class inventory · 2026-05-15
adenosine
Adenocard
Adenosine (Adenocard) is a medicine used to treat certain types of irregular heartbeats.
View details →
amiodarone
Cordarone, Pacerone
Amiodarone (Pacerone) is a medicine used to treat life-threatening, irregular heartbeats.
View details →
atropine
AtroPen
Atropine is a medicine that can temporarily block severe effects on your body.
View details →
bumetanide
Bumex
Bumetanide is a water pill (diuretic).
View details →
carvedilol
Coreg
Carvedilol is a medicine that lowers blood pressure and helps your heart work better.
View details →
digoxin
Lanoxin
Digoxin (Lanoxin) is a medicine that helps your heart pump better.
View details →
dobutamine
Dobutrex
Dobutamine is a medicine that helps your heart pump better.
View details →
dofetilide
Tikosyn
Dofetilide (Tikosyn) helps keep your heart in a normal rhythm if you have atrial fibrillation or atrial flutter.
View details →
dopamine
Intropin
Dopamine injection helps improve blood flow in patients suffering from shock.
View details →
dronedarone
Multaq
Multaq is a medicine that helps lower the risk of needing to stay in the hospital for atrial fibrillation (AFib).
View details →
epinephrine
EpiPen, Adrenalin
Epinephrine injection is a medicine that raises blood pressure.
View details →
ethacrynic acid
Edecrin
Ethacrynic acid (Edecrin) is a strong diuretic, also known as a water pill.
View details →
flecainide
Tambocor
Flecainide is a medicine used to prevent irregular heartbeats.
View details →
furosemide
Lasix
Furosemide is a water pill (diuretic).
View details →
hydralazine/isosorbide dinitrate
BiDil
BiDil is a medicine that combines two drugs to help treat heart failure.
View details →
isosorbide dinitrate
Isordil
Isosorbide dinitrate is a medicine that helps prevent chest pain (angina).
View details →
isosorbide mononitrate
Imdur
Isosorbide mononitrate is a medicine that helps prevent chest pain.
View details →
ivabradine
Corlanor
Ivabradine (Corlanor) is a medicine that helps lower the risk of needing to go to the hospital for worsening heart failure.
View details →
mexiletine
Mexitil
Mexiletine is a medicine used to treat life-threatening heart rhythm problems.
View details →
milrinone
Primacor
Milrinone is a medicine used in the hospital for a short time to help people with severe heart failure.
View details →
nitroglycerin
Nitrostat, Nitro-Dur
Nitroglycerin sublingual tablets help to relieve chest pain (angina) due to heart disease.
View details →
norepinephrine
Levophed
Norepinephrine injection raises blood pressure in adults with very low blood pressure.
View details →
phenylephrine
Neo-Synephrine
Phenylephrine is a medicine that helps relieve cold and flu symptoms.
View details →
propafenone
Rythmol
Propafenone (Rythmol) is a medicine that helps control irregular heartbeats.
View details →
ranolazine
Ranexa
Ranolazine extended-release tablets help treat chronic angina (chest pain).
View details →
sacubitril/valsartan
Entresto
Entresto is a medicine that combines two drugs to help adults and children with heart failure.
View details →
sotalol
Betapace
Sotalol is a medicine that helps keep your heart beating regularly.
View details →
spironolactone
Aldactone
Spironolactone is a medicine that helps remove extra fluid from your body and lower blood pressure.
View details →
torsemide
Demadex
Torsemide is a water pill (diuretic).
View details →
vasopressin
Vasostrict
Vasopressin injection helps raise blood pressure in adults with shock.
View details →
vericiguat
Verquvo
Verquvo is a medicine that helps lower the risk of death and hospitalization from heart failure.
View details →
Heart · mid-corpus inventory (#11 of 22)
Heart is inventory #11 of 22 (31 drugs) ≠ FAERS-volume #10. Nationally Mental Health is inventory #1 of 22 (77 drugs) ≠ Pain Relief FAERS-volume #1 at inventory #3. 31 medicines tracked; 27 carry a NADAC generic flag; 6 in active FDA shortage.
Classes nearest Heart by inventory size
Read our methodology - how this data is sourced, computed, and verified.