Prescription medication · Phosphonic Acid Antibiotic
fosfomycin
Also sold as Monurol. This medicine treats uncomplicated urinary tract infections (UTIs) in women.
Data updated 2026-05-15
- 2
- InteractionsFew interactions
- $41.92
- Generic price (NADAC)
fosfomycin (Monurol) is a prescription Phosphonic Acid Antibiotic. This medicine treats uncomplicated urinary tract infections (UTIs) in women.
Fosfomycin is an antibiotic medicine. It is used to treat bladder infections in women.
Verify with FDA → · CMS NADAC pricing →
Drug Pricing (NADAC)
Generic Price
$41.92/unit
Generic Available
Yes (6 manufacturers)
Pricing data from NADAC (CMS), effective December 18, 2024. Compare all drug costs →
NADAC price trail: FOSFOMYCIN 3 GM SACHET
Same CMS presentation as the headline generic unit price above (2 effective dates). Adjacent % compares consecutive NADAC releases for this description only, not a patient out-of-pocket quote. Latest step: -13.9% vs prior release.
| Effective | NADAC / unit | vs prior | NDCs |
|---|---|---|---|
| October 23, 2024 | $48.68/EA | - | 2 |
| December 18, 2024 | $41.92/EA | -13.9% | 4 |
What it does
This medicine treats uncomplicated urinary tract infections (UTIs) in women.
Common side effects
Diarrhea, Vaginal inflammation (vaginitis), Nausea
Key warnings
You should not take this medicine if you are allergic to fosfomycin.
The sections below are summarized in plain English from fosfomycin's FDA-approved prescribing information. They describe what the official label says, and are not personal medical advice.
How It Works
Fosfomycin is an antibiotic that kills bacteria. It stops bacteria from building cell walls. Without a cell wall, the bacteria cannot survive.
Serious Warnings
You should not take this medicine if you are allergic to fosfomycin.
Known Drug Interactions
Cimetidine: Cimetidine does not affect the pharmacokinetics of fosfomycin when coadministered with fosfomycin tromethamine.
Mechanism: Cimetidine does not change the way the body absorbs or gets rid of fosfomycin.
DRUG INTERACTIONS Metoclopramide: When coadministered with fosfomycin tromethamine, metoclopramide, a drug which increases gastrointestinal motility, lowers the serum concentration and urinary excretion of fosfomycin.
Mechanism: Metoclopramide speeds up how fast your stomach and intestines move, which gives your body less time to absorb the fosfomycin. This results in lower levels of the antibiotic in your blood and urine.
This is a plain-language summary of FDA-label interaction records and does not provide individual medication-combination directions.
Common Questions
Can I take this medicine if I have a kidney infection?
Can men take this medication?
What should I do if my symptoms don't improve?
Can I mix the granules with something other than water?
Can I take this medicine if I am allergic to penicillin?
Will this medicine interact with other medications I am taking?
Can I take this medication while pregnant?
How quickly does this medicine work?
Can I take this medication if I have a fever?
Is it safe to drink alcohol while taking fosfomycin?
What are the common side effects of fosfomycin?
Does fosfomycin interact with other medications?
What drug class is fosfomycin?
What pregnancy or breastfeeding source fields are listed for fosfomycin?
Related Medications in Phosphonic Acid Antibiotic
Other drugs grouped near fosfomycin - same-class peers and common alternatives.
amikacin
Amikin
Amikacin is an antibiotic medicine.
Compare with fosfomycin →
amoxicillin
Amoxil
Amoxicillin and Clavulanate Potassium is a combination medicine used to fight bacterial infections.
Compare with fosfomycin →
amoxicillin/clavulanate
Augmentin
Augmentin is a combination of two medicines, amoxicillin and clavulanate.
Compare with fosfomycin →
ampicillin/sulbactam
Unasyn
Unasyn is a combination of two antibiotics that fights bacteria in your body.
Compare with fosfomycin →
azithromycin
Zithromax, Z-Pack
Azithromycin is an antibiotic that fights bacteria.
Compare with fosfomycin →
Medication Guides
Understanding Drug Interactions
How CYP450 enzymes, inhibitors, and inducers affect your medications
Generic vs Brand Name Drugs
FDA requirements, cost savings, and when the difference matters
Narrow Therapeutic Index Drugs
FDA bioequivalence and label-record context for narrow therapeutic index medicines
Common Drug Interactions
Dangerous medication combinations and how to protect yourself
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What the FDA Data Shows for fosfomycin
The FDA label for fosfomycin (sold under brand names such as Monurol) classifies it as a prescription-only medication in the Phosphonic Acid Antibiotic class. This medicine treats uncomplicated urinary tract infections (UTIs) in women. Official labeling lists 5 commonly reported side effects, including Diarrhea, Vaginal inflammation (vaginitis), Nausea.
Post-market surveillance from the FDA Adverse Event Reporting System (FAERS) captures real-world experience. Voluntary reports accumulate over the lifetime of a drug and reflect wide-ranging clinical use. The database also lists 2 documented drug interactions derived from FDA labeling, with the top-flagged interaction rated minor severity. NADAC pricing from CMS shows a generic unit cost of $41.92.
Report counts do not establish causation, a FAERS entry documents a temporal association, not proof that the drug produced the outcome. Widely prescribed medications naturally accumulate more reports than niche therapies, so raw totals must be interpreted alongside total exposure. Shortage status, recall history, and patent information are separate source-record fields. This page is a public FDA/CMS registry and does not provide medical, treatment, substitution, or medication-change directions.
Data Sources
Drug labeling: FDA Drug Labels (SPL/DailyMed). Adverse events: FDA Adverse Event Reporting System (FAERS). Pricing: CMS National Average Drug Acquisition Cost (NADAC).
FAERS reports are voluntary and do not establish causation. Drug interactions are derived from FDA labeling and clinical references. This registry does not provide medication decisions.
Last updated: September 25, 2025
PlainMeds is rendered directly from FDA openFDA/FAERS extracts, DailyMed labels, and CMS drug-pricing files, no number is typed in by an editor. FAERS counts, recalls, shortages, and price figures on this page are queried live from those federal extracts. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error. Data current as of 2026-05-15. Primary sources: openFDA / FAERS, DailyMed and CMS Part B ASP.
Read our methodology - how this data is sourced, computed, and verified.
Data currency: FDA FAERS adverse-event reports through 2025, CMS NADAC acquisition-cost pricing effective December 2024, compiled from the source snapshot dated . See our methodology for per-source dates and refresh cadence. Spot a figure that looks wrong? Report a data issue.
All federal data sources used on this page
- FDA Orange Book - approved drug products with therapeutic equivalence. accessdata.fda.gov/cder/ob
- FDA DailyMed - NIH-hosted drug labeling for FDA-approved meds. dailymed.nlm.nih.gov
- FDA Adverse Event Reporting System (FAERS) - post-marketing safety surveillance. fda.gov/drugs/faers
- NLM RxNorm - standardized clinical drug nomenclature. nlm.nih.gov/research/umls/rxnorm
- CMS Medicare Part B Drug Average Sales Price Files - federal drug pricing data. cms.gov/medicare/part-b-drugs/asp
- FDA Drug Shortages Database - current and resolved drug shortage tracking. accessdata.fda.gov/drugshortages