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dalbavancin

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Brand names: Dalvance

Lipoglycopeptide Antibiotic Rx

Dalbavancin is an antibiotic medicine. It fights bacterial infections of the skin and tissues under the skin.

What it does

Dalbavancin treats acute bacterial skin and skin structure infections (ABSSSI).

Common side effects

Nausea, Headache, Diarrhea

Key warnings

Serious allergic reactions and skin reactions have been reported.

How It Works

Dalbavancin is a lipoglycopeptide antibiotic. It works by stopping bacteria from growing. This helps your body fight off the infection.

How to Take It

Dalbavancin is given through a vein (IV). It's usually given as a single dose. The IV infusion takes 30 minutes. The dose depends on your kidney function and weight.

Pregnancy & Breastfeeding

It is not known if dalbavancin will harm an unborn baby. Talk to your doctor if you are pregnant or plan to become pregnant. It is also not known if dalbavancin passes into breast milk. Talk to your doctor about the best way to feed your baby if you take this medicine.

Missed Dose

Since dalbavancin is usually given as a single dose, you don't have to worry about missed doses.

Storage

Store dalbavancin at room temperature (between 59ºF and 86ºF).

Side Effects (from patient reports)

Based on 623 FDA adverse event reports.

Off Label Use
138
Rash
93
Back Pain
55
Pruritus
55
Dyspnoea
53
Drug Ineffective
51
Nausea
49
Hypersensitivity
45
Erythema
42
Vomiting
42

FDA Adverse Event Report Analysis

Detailed analysis of 911 reports from the FDA Adverse Event Reporting System (FAERS). Reports span 2014–2025.

Total Reports

911

Death-Related Reports

20

Hospitalization Reports

207

Top Indication

Product Used For Unknown Indication

Gender Distribution

Female 331 (48%)
Male 352 (51%)

Age Distribution

0–17 24
18–44 105
45–64 164
65–74 85
75+ 95

Most Reported Adverse Reactions (FAERS)

# Reaction Reports
1 OFF LABEL USE 138
2 RASH 93
3 BACK PAIN 55
4 PRURITUS 55
5 DYSPNOEA 53
6 DRUG INEFFECTIVE 51
7 NAUSEA 49
8 HYPERSENSITIVITY 45
9 ERYTHEMA 42
10 VOMITING 42
11 URTICARIA 37
12 CHEST DISCOMFORT 28
13 INFUSION RELATED REACTION 28
14 DIARRHOEA 26
15 PYREXIA 25

Reactions in Death Reports

DEATH 14
OFF LABEL USE 3
TREATMENT FAILURE 3
PYREXIA 2
CEREBROVASCULAR ACCIDENT 1
CHILLS 1
DRUG DOSE OMISSION 1
DRUG INEFFECTIVE 1
EMBOLISM 1
HAEMORRHAGE 1

Reactions in Hospitalization Reports

DRUG INEFFECTIVE 25
OFF LABEL USE 25
DYSPNOEA 18
PYREXIA 15
NAUSEA 14
HYPERSENSITIVITY 13
ACUTE KIDNEY INJURY 12
RASH 12
ANAPHYLACTIC REACTION 11
INFUSION RELATED REACTION 11

Source: FDA FAERS (Adverse Event Reporting System) FDA FAERS (Adverse Event Reporting System) Reports are voluntary and do not establish causation

Serious Warnings

Serious allergic reactions and skin reactions have been reported. Tell your doctor right away if you have any signs of an allergic reaction. Rapid IV infusion can cause flushing, rash, itching, and back pain. Slowing the infusion may help.

Common Questions

What if I am allergic to glycopeptide antibiotics?
Tell your doctor if you've had allergic reactions to glycopeptide antibiotics like vancomycin. You will be watched closely for any signs of a reaction.
Can dalbavancin cause diarrhea?
Yes, dalbavancin and other antibiotics can cause diarrhea. Tell your doctor if you develop diarrhea, especially if it is severe or bloody.
Will dalbavancin affect my liver?
Dalbavancin can cause changes in liver function tests. Your doctor may check your liver function while you are taking this medicine.
Can children take dalbavancin?
Yes, dalbavancin can be used in children for skin infections. The dose will be based on the child's weight and age.
What if my kidneys don't work well?
If your kidneys don't work well, your doctor may need to adjust your dose.
Are there any drug interactions?
There are no known major drug interactions with dalbavancin.
How will I receive dalbavancin?
Dalbavancin is given through an IV (intravenous infusion) into your vein.
How long does the infusion take?
The IV infusion takes 30 minutes.
What if I experience flushing or itching during the infusion?
Tell the nurse or doctor right away. They may slow down or stop the infusion.
What kind of bacteria does dalbavancin treat?
Dalbavancin treats infections caused by certain Gram-positive bacteria, such as Staphylococcus and Streptococcus.
What are the common side effects of dalbavancin?
The most commonly reported side effects of dalbavancin include Nausea, Headache, Diarrhea. Based on 623 FDA adverse event reports. Always consult your healthcare provider about potential side effects.
What drug class is dalbavancin?
dalbavancin belongs to the Lipoglycopeptide Antibiotic drug class. It requires a prescription (Rx). Dalbavancin treats acute bacterial skin and skin structure infections (ABSSSI).
Is dalbavancin safe during pregnancy?
It is not known if dalbavancin will harm an unborn baby. Talk to your doctor if you are pregnant or plan to become pregnant. Always consult your healthcare provider before using any medication during pregnancy or breastfeeding.

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What the FDA Data Shows for dalbavancin

The FDA label for dalbavancin (sold under brand names such as Dalvance) classifies it as a prescription-only medication in the Lipoglycopeptide Antibiotic class. Dalbavancin treats acute bacterial skin and skin structure infections (ABSSSI). Official labeling lists 3 commonly reported side effects, including Nausea, Headache, Diarrhea.

Post-market surveillance from the FDA Adverse Event Reporting System (FAERS) captures real-world experience. For this drug, FAERS contains 623 voluntary reports. Interaction data is drawn directly from FDA-approved prescribing information. Acquisition-cost data is surveyed weekly by CMS and updated as manufacturers report changes.

Report counts do not establish causation — a FAERS entry documents a temporal association, not proof that the drug produced the outcome. Widely prescribed medications naturally accumulate more reports than niche therapies, so raw totals must be interpreted alongside total exposure. Shortage status, recall history, and patent information further shape supply and switching decisions. This page summarizes public FDA data for educational purposes only and is not a substitute for professional medical advice — always consult a licensed healthcare provider before starting, stopping, or changing any medication.

Data Sources

Drug labeling: FDA Drug Labels (SPL/DailyMed). Adverse events: FDA Adverse Event Reporting System (FAERS).

FAERS reports are voluntary and do not establish causation. Drug interactions are derived from FDA labeling and clinical references. Always consult a healthcare professional before making medication decisions.

Last updated: October 6, 2025

All federal data sources used on this page