Prescription medication · Aminoglycoside Antibiotic
gentamicin
Also sold as Garamycin. Gentamicin treats serious infections caused by certain bacteria.
Data updated 2026-05-15
- 12,687
- FDA reportsModerately reported
- 7
- InteractionsFew interactions
- 2
- Recall records
What the data shows
gentamicin (Garamycin) is a prescription Aminoglycoside Antibiotic, reported less often than most tracked drugs (12,687 FDA reports), with 7 documented drug interactions.
Reporting volume reflects how widely a drug is used and studied, not how dangerous it is, a FAERS report documents a temporal association, never proof of cause.
gentamicin (Garamycin) is a prescription Aminoglycoside Antibiotic. Gentamicin treats serious infections caused by certain bacteria.
Gentamicin is an antibiotic medicine. It fights serious infections caused by certain bacteria.
Verify with FDA → · CMS NADAC pricing →
Drug Pricing (NADAC)
Generic Price
$0.77/unit
Generic Available
Yes (12 manufacturers)
Pricing data from NADAC (CMS), effective December 18, 2024. Compare all drug costs →
What it does
Gentamicin treats serious infections caused by certain bacteria.
Common side effects
No common side effects listed.
Key warnings
Gentamicin can potentially damage kidneys and cause nerve damage, including hearing loss.
The sections below are summarized in plain English from gentamicin's FDA-approved prescribing information. They describe what the official label says, and are not personal medical advice.
How It Works
Gentamicin belongs to a class of drugs called aminoglycoside antibiotics. It works by stopping the growth of bacteria. This helps your body fight off the infection.
Side Effects (from patient reports)
Based on 12,687 FDA adverse event reports.
Most-reported reactions
Adverse reactions in FAERS for gentamicin, by number of reports
- Acute Kidney Injury
Acute Kidney Injury
999 reports
- Pyrexia
Pyrexia
750 reports
- Renal Failure
Renal Failure
604 reports
- Diarrhoea
Diarrhoea
460 reports
- Sepsis
Sepsis
426 reports
- Condition Aggravated
Condition Aggravated
404 reports
- Chronic Kidney Disease
Chronic Kidney Disease
402 reports
- Hypotension 399
Hypotension
399 reports
- Drug Interaction 375
Drug Interaction
375 reports
- Nausea 373
Nausea
373 reports
What this shows Bars show how often each reaction was reported, not how likely it is to happen, a report records a temporal association, never proof that the drug caused it.
Reports over time
Adverse-event reports filed for gentamicin each year to the FDA Adverse Event Reporting System (FAERS).
Year-to-year volume tracks usage, prescribing, and scrutiny, not a change in per-patient risk. Source: FDA FAERS.
Where gentamicin sits
gentamicin has more FDA adverse-event reports than 44% of the drugs FAERS tracks. A high position reflects how widely a drug is used and watched, not how dangerous it is.
Percentile across all drugs PlainMeds tracks by FAERS report volume. The dot is gentamicin; the line is the median (50th percentile).
FDA Adverse Event Report Analysis
Detailed analysis of 12,687 reports from the FDA Adverse Event Reporting System (FAERS). Reports span 1999–2025.
Total Reports
12,687
Reports Mentioning Death
2,366
18.6% of reports — not proof of cause
Hospitalization Reports
6,198
Top Indication
Product Used For Unknown Indication
Gender Distribution
Age Distribution
Most Reported Adverse Reactions (FAERS)
| # | Reaction | Reports |
|---|---|---|
| 2 | ACUTE KIDNEY INJURY | 999 |
| 3 | PYREXIA | 750 |
| 5 | RENAL FAILURE | 604 |
| 6 | DIARRHOEA | 460 |
| 7 | SEPSIS | 426 |
| 8 | CONDITION AGGRAVATED | 404 |
| 9 | CHRONIC KIDNEY DISEASE | 402 |
| 10 | HYPOTENSION | 399 |
| 11 | DRUG INTERACTION | 375 |
| 12 | NAUSEA | 373 |
| 13 | RENAL FAILURE ACUTE | 359 |
| 14 | FOETAL EXPOSURE DURING PREGNANCY | 358 |
| 15 | PREMATURE BABY | 345 |
| 16 | DYSPNOEA | 337 |
| 17 | FATIGUE | 334 |
Reactions in Death Reports
Reactions in Hospitalization Reports
Source: FDA FAERS (Adverse Event Reporting System) Reports are voluntary and do not establish causation
Serious Warnings
Gentamicin can potentially damage kidneys and cause nerve damage, including hearing loss. The risk is higher if you have kidney problems, receive high doses, or take it for a long time. Tell your doctor right away if you notice dizziness, ringing in your ears, changes in hearing, or kidney problems.
Known Drug Interactions
Nephrotoxic agents Concomitant administration of cidofovir injection and agents with nephrotoxic potential [e.g., intravenous aminoglycosides (e.g., tobramycin, gentamicin, and amikacin), amphotericin B, foscarnet, intravenous pentamidine, vancomycin, and nonsteroidal anti-inflammatory agents] is contraindicated.
Mechanism: These medications are both known to be toxic to the kidneys. Using them together can cause severe kidney problems.
Some examples of drugs that are eliminated by active tubular secretion include, but are not limited to, acyclovir, cidofovir, ganciclovir, valacyclovir, valganciclovir, aminoglycosides (e.g., gentamicin), and high-dose or multiple NSAIDs [see Warnings and Precautions (5.4) ] .
Mechanism: Both drugs are removed from the body through the same pathway in the kidneys. Taking them together may cause the drugs to build up in your system.
Captopril 58% 39% Clarithromycin NA 70% Dronedarone NA 150% Gentamicin 129-212% NA Erythromycin 100% NA Itraconazole 80% NA Lapatinib NA 180% Propafenone NA 60-270% Quinidine 100% NA Ranolazine 50% NA Ritonavir NA 86% Telaprevir 50% 85% Tetracycline 100% NA Verapamil 50-75% NA Digoxin concentrations increased less than 50% Atorvastatin 22% 15% Carvedilol 16% 14% Measure serum digoxin concentrations before initiating concomitant drugs.
Mechanism: Gentamicin can significantly increase the amount of digoxin in your blood, sometimes doubling it or more. This happens because the antibiotic affects how your body clears the heart medicine.
Some examples include, but are not limited to, acyclovir, adefovir dipivoxil, cidofovir, ganciclovir, valacyclovir, valganciclovir, aminoglycosides (e.g., gentamicin), and high-dose or multiple NSAIDs [see Warnings and Precautions (5.3) ] .
Mechanism: Both of these drugs are removed from the body through the kidneys. Taking them at the same time can increase the risk of kidney damage or raise drug levels in your blood.
7.6 Gentamicin Animal data have suggested the possibility of interaction between perindopril and gentamicin.
Mechanism: Research in animals suggests these two drugs might interact, although the exact way they affect humans is not yet fully understood.
This is a plain-language summary of FDA-label interaction records and does not provide individual medication-combination directions.
Common Questions
What should I tell my doctor before taking gentamicin?
Can gentamicin interact with other medications?
How will my doctor monitor me while I'm taking gentamicin?
What are the signs of kidney problems?
What are the signs of hearing problems?
Can gentamicin cause any other side effects?
What if I overdose on gentamicin?
Can I take gentamicin if I am allergic to other medications?
How long will I need to take gentamicin?
What if my symptoms don't improve?
Does gentamicin interact with other medications?
What drug class is gentamicin?
What pregnancy or breastfeeding source fields are listed for gentamicin?
Has gentamicin been recalled?
Active Recalls
Lack of Assurance of Sterility: FDA inspection findings resulted in concerns regarding quality control processes
Lowlite Investments, Inc. D/B/A Olympia Pharmacy
Lack of Assurance of Sterility: FDA inspection findings resulted in concerns regarding quality control processes
Lowlite Investments, Inc. D/B/A Olympia Pharmacy
Related Medications in Aminoglycoside Antibiotic
Other drugs grouped near gentamicin - same-class peers and common alternatives.
amikacin
Amikin
Amikacin is an antibiotic medicine.
Compare with gentamicin →
amoxicillin
Amoxil
Amoxicillin and Clavulanate Potassium is a combination medicine used to fight bacterial infections.
Compare with gentamicin →
amoxicillin/clavulanate
Augmentin
Augmentin is a combination of two medicines, amoxicillin and clavulanate.
Compare with gentamicin →
ampicillin/sulbactam
Unasyn
Unasyn is a combination of two antibiotics that fights bacteria in your body.
Compare with gentamicin →
azithromycin
Zithromax, Z-Pack
Azithromycin is an antibiotic that fights bacteria.
Compare with gentamicin →
Compare beyond drug class
Nationwide peers by FAERS volume & death-report share
Two PlainMeds-derived comparison paths for gentamicin: nearest FDA FAERS report volume and nearest death-report share among drugs with at least 1,000 logged reports, excluding same-class neighbors listed above. Counts reflect reporting volume, not proven individual harm.
Similar FAERS report volume
Nearest drugs by total FAERS reports. This record: 12,687.
Similar death-report share
Nearest drugs by FAERS death-report share. This record: 18.65%.
- phytonadione Δ 0.02 pts · 8,078 reports · Vitamin K Supplement 18.67%death share
- linezolid Δ 0.07 pts · 28,005 reports · Oxazolidinone Antibiotic 18.58%death share
- chlorpromazine Δ 0.08 pts · 6,862 reports · Typical Antipsychotic (Phenothiazine) 18.73%death share
- diphenhydramine Δ 0.12 pts · 60,533 reports · First-Generation Antihistamine 18.77%death share
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Narrow Therapeutic Index Drugs
FDA bioequivalence and label-record context for narrow therapeutic index medicines
Common Drug Interactions
Dangerous medication combinations and how to protect yourself
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What the FDA Data Shows for gentamicin
The FDA label for gentamicin (sold under brand names such as Garamycin) classifies it as a prescription-only medication in the Aminoglycoside Antibiotic class. Gentamicin treats serious infections caused by certain bacteria. Labeling covers dosing, contraindications, and monitoring requirements derived from clinical trials.
Post-market surveillance from the FDA Adverse Event Reporting System (FAERS) captures real-world experience. For this drug, FAERS contains 12,687 voluntary reports. The database also lists 7 documented drug interactions derived from FDA labeling, with the top-flagged interaction rated major severity. NADAC pricing from CMS shows a generic unit cost of $0.77.
Report counts do not establish causation, a FAERS entry documents a temporal association, not proof that the drug produced the outcome. Widely prescribed medications naturally accumulate more reports than niche therapies, so raw totals must be interpreted alongside total exposure. Shortage status, recall history (currently 2 recall records on file), and patent information are separate source-record fields. This page is a public FDA/CMS registry and does not provide medical, treatment, substitution, or medication-change directions.
Data Sources
Drug labeling: FDA Drug Labels (SPL/DailyMed). Adverse events: FDA Adverse Event Reporting System (FAERS). Pricing: CMS National Average Drug Acquisition Cost (NADAC).
FAERS reports are voluntary and do not establish causation. Drug interactions are derived from FDA labeling and clinical references. This registry does not provide medication decisions.
Last updated: November 10, 2023
PlainMeds is rendered directly from FDA openFDA/FAERS extracts, DailyMed labels, and CMS drug-pricing files, no number is typed in by an editor. FAERS counts, recalls, shortages, and price figures on this page are queried live from those federal extracts. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error. Data current as of 2026-05-15. Primary sources: openFDA / FAERS, DailyMed and CMS Part B ASP.
Read our methodology - how this data is sourced, computed, and verified.
Data currency: FDA FAERS adverse-event reports through 2025, CMS NADAC acquisition-cost pricing effective December 2024, compiled from the source snapshot dated . See our methodology for per-source dates and refresh cadence. Spot a figure that looks wrong? Report a data issue.
All federal data sources used on this page
- FDA Orange Book - approved drug products with therapeutic equivalence. accessdata.fda.gov/cder/ob
- FDA DailyMed - NIH-hosted drug labeling for FDA-approved meds. dailymed.nlm.nih.gov
- FDA Adverse Event Reporting System (FAERS) - post-marketing safety surveillance. fda.gov/drugs/faers
- NLM RxNorm - standardized clinical drug nomenclature. nlm.nih.gov/research/umls/rxnorm
- CMS Medicare Part B Drug Average Sales Price Files - federal drug pricing data. cms.gov/medicare/part-b-drugs/asp
- FDA Drug Shortages Database - current and resolved drug shortage tracking. accessdata.fda.gov/drugshortages