Medication class
Skin
Topical and oral medications for acne, eczema, psoriasis, fungal infections, and other dermatological conditions.
Data updated 2026-05-15
- 41
- Medications
- 27
- With a generic
- 88%
- Avg generic savings
- 1
- In active shortage
Drug class assignments follow the FDA openFDA therapeutic classification, clinical details are drawn from FDA Structured Product Labeling via DailyMed, and unit-price comparisons use CMS National Average Drug Acquisition Cost data. See the full sources below.
Inventory versus report volume
Skin is inventory #6 of 22 (largest of 2 at 41 drugs) ≠ FAERS-volume #13. Nationally Mental Health is inventory #1 of 22 (77 drugs) ≠ Pain Relief FAERS-volume #1 at inventory #3.
- #6
- inventory
- 41
- tracked drugs
- #13
- FAERS volume
- #1
- Pain Relief FAERS nationally
According to FDA FAERS report totals and openFDA class inventory compiled on /methodology. Class size is not the same map as report volume. This page is for informational purposes only and is not medical advice.
This class - generic availability cut
Exclusive DISTINCT-drug split of 41 medicines in Skin. Orthogonal to inventory vs FAERS dual and to the NADAC cost ChartBar.
ustekinumab tops Skin NADAC at $26795.00/unit
Top 10 acquisition costs in this class (CMS NADAC)
- ustekinumab
ustekinumab
$26,795 per unit
- risankizumab
risankizumab
$20,212 per unit
- guselkumab
guselkumab
$13,351 per unit
- ixekizumab $6,682
ixekizumab
$6,682 per unit
- apremilast $88
apremilast
$88 per unit
- isotretinoin $36
isotretinoin
$36 per unit
- ruxolitinib topical $33
ruxolitinib topical
$33 per unit
- imiquimod $23
imiquimod
$23 per unit
- calcipotriene/betamethasone $21
calcipotriene/betamethasone
$21 per unit
- tazarotene $10
tazarotene
$10 per unit
What this shows ustekinumab is the costliest in this class at $26795.00/unit; generics in the same class run a fraction of that.
Skin · #7 inventory of 22 therapeutic classes
15 classes have fewer tracked drugs; percentile 68 among PlainMeds categories.
Skin vs all classes by tracked-drug count
Where this class's inventory sits among every PlainMeds therapeutic category
41 7th of 22 higher than 15 of 22 classes
Classes, banded by tracked-drug inventory
Each bar is a band; taller bars hold more classes. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source PlainMeds openFDA therapeutic-class inventory · 2026-05-15
adapalene OTC
Differin
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apremilast
Otezla
Apremilast (Otezla/Otezla XR) is a medicine that can help adults and children manage psoriatic arthritis and psoriasis.
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azelaic acid
Finacea, Azelex
Azelaic acid gel is a topical medicine that helps treat rosacea.
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benzoyl peroxide OTC
Benzac, PanOxyl
Benzoyl peroxide is a topical medicine that fights germs on your skin.
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betamethasone
Diprosone, Luxiq
Betamethasone dipropionate cream is a strong steroid medicine used on the skin.
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brodalumab
Siliq
Siliq is a medicine used to treat moderate to severe plaque psoriasis.
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calcipotriene
Dovonex
Calcipotriene and Betamethasone Dipropionate Ointment is a medicine that contains a vitamin D-like drug and a steroid.
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calcipotriene/betamethasone
Enstilar, Taclonex
Calcipotriene and Betamethasone Dipropionate Ointment is a medicine that combines a vitamin D-like drug and a steroid.
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clindamycin topical
Cleocin T, Clindagel
Clindamycin topical (Cleocin T) is a medicine you put on your skin to treat acne.
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clobetasol
Temovate, Clobex
Clobetasol ointment is a very strong steroid medicine used on the skin.
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crisaborole
Eucrisa
Eucrisa is a medicine used on the skin to treat eczema.
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cyclosporine
Neoral, Sandimmune, Restasis
Vevye eye drops contain cyclosporine.
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dapsone topical
Aczone
Aczone Gel is a topical medicine used to treat acne.
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desonide
DesOwen
Desonide cream is a low-strength steroid medicine.
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desoximetasone
Topicort
Desoximetasone is a steroid medicine that you put on your skin.
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erythromycin topical
Erygel
Erythromycin topical solution is a medicine that you put on your skin to treat acne.
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fluocinolone
Synalar, Derma-Smoothe
Fluocinolone is a topical steroid medicine.
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fluocinonide
Lidex, Vanos
Fluocinonide is a strong topical steroid medicine.
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fluorouracil topical
Efudex
Fluorouracil topical (Efudex) is a skin cream that treats certain skin conditions.
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guselkumab
Tremfya
Tremfya is a medicine that can help treat plaque psoriasis, psoriatic arthritis, ulcerative colitis, and Crohn's disease.
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halobetasol
Ultravate
Halobetasol Propionate Ointment is a strong steroid medicine used on the skin.
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hydrocortisone OTC
Cortef
Hydrocortisone cream helps relieve itching and skin problems.
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imiquimod
Aldara
Imiquimod cream helps your immune system fight certain skin problems.
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isotretinoin
Accutane, Absorica
Isotretinoin capsules are a strong medicine used to treat severe acne.
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ivermectin topical
Soolantra
Soolantra cream contains ivermectin and is used on the skin.
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ixekizumab
Taltz
Taltz is a medicine that can help treat plaque psoriasis, psoriatic arthritis, ankylosing spondylitis, and non-radiographic axial spondyloarthritis.
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ketoconazole OTC
Nizoral
Ketoconazole shampoo is an antifungal medicine.
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metronidazole topical
MetroGel
Metronidazole gel is a medicine that you put on your skin.
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minoxidil topical OTC
Rogaine
Minoxidil topical solution (Rogaine) is a medicine that helps regrow hair on your scalp.
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mometasone topical
Elocon
Mometasone Furoate Cream is a medicine that reduces skin inflammation and itching.
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mupirocin
Bactroban
Mupirocin cream is a topical antibiotic.
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permethrin OTC
Elimite, Nix
Permethrin cream rinse is a medicine that kills lice and their eggs.
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pimecrolimus
Elidel
Pimecrolimus cream (Elidel) is a medicine that can help with eczema.
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risankizumab
Skyrizi
Skyrizi is a medicine that can help reduce inflammation in your body.
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ruxolitinib topical
Opzelura
Opzelura is a cream that contains ruxolitinib.
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spironolactone (acne)
Aldactone
Spironolactone (Aldactone) is a medicine that helps remove extra fluid from your body and lower blood pressure.
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tacrolimus topical
Protopic
Tacrolimus extended-release capsules help prevent organ rejection in kidney transplant patients.
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tazarotene
Tazorac
Tazorac Cream contains tazarotene, a retinoid medicine.
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tretinoin
Retin-A
Tretinoin capsules help put acute promyelocytic leukemia (APL) into remission.
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triamcinolone OTC
Kenalog, Aristocort
Triamcinolone Acetonide Ointment is a steroid medicine that reduces inflammation and itching.
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ustekinumab
Stelara
Ustekinumab-aekn (Stelara) is a medicine that helps control inflammation in your body.
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Skin · large class with 1 active shortage
Skin is inventory #6 of 22 (largest of 2 at 41 drugs) ≠ FAERS-volume #13. Nationally Mental Health is inventory #1 of 22 (77 drugs) ≠ Pain Relief FAERS-volume #1 at inventory #3. 41 medicines tracked; 27 carry a NADAC generic flag; 1 in active FDA shortage.
Classes nearest Skin by inventory size
Read our methodology - how this data is sourced, computed, and verified.