Medication class

Skin

Topical and oral medications for acne, eczema, psoriasis, fungal infections, and other dermatological conditions.

Data updated 2026-05-15

41
Medications
27
With a generic
88%
Avg generic savings
1
In active shortage

Drug class assignments follow the FDA openFDA therapeutic classification, clinical details are drawn from FDA Structured Product Labeling via DailyMed, and unit-price comparisons use CMS National Average Drug Acquisition Cost data. See the full sources below.

Inventory versus report volume

Skin is inventory #6 of 22 (largest of 2 at 41 drugs) ≠ FAERS-volume #13. Nationally Mental Health is inventory #1 of 22 (77 drugs) ≠ Pain Relief FAERS-volume #1 at inventory #3.

#6
inventory
41
tracked drugs
#13
FAERS volume
#1
Pain Relief FAERS nationally

According to FDA FAERS report totals and openFDA class inventory compiled on /methodology. Class size is not the same map as report volume. This page is for informational purposes only and is not medical advice.

This class - generic availability cut

Exclusive DISTINCT-drug split of 41 medicines in Skin. Orthogonal to inventory vs FAERS dual and to the NADAC cost ChartBar.

ustekinumab tops Skin NADAC at $26795.00/unit

Top 10 acquisition costs in this class (CMS NADAC)

per unit

What this shows ustekinumab is the costliest in this class at $26795.00/unit; generics in the same class run a fraction of that.

Source CMS National Average Drug Acquisition Cost (NADAC)

Skin · #7 inventory of 22 therapeutic classes

15 classes have fewer tracked drugs; percentile 68 among PlainMeds categories.

Skin vs all classes by tracked-drug count

Where this class's inventory sits among every PlainMeds therapeutic category

41 7th of 22 higher than 15 of 22 classes

Classes, banded by tracked-drug inventory

Each bar is a band; taller bars hold more classes. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source PlainMeds openFDA therapeutic-class inventory · 2026-05-15

adapalene OTC

Differin

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apremilast

Otezla

Apremilast (Otezla/Otezla XR) is a medicine that can help adults and children manage psoriatic arthritis and psoriasis.

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azelaic acid

Finacea, Azelex

Azelaic acid gel is a topical medicine that helps treat rosacea.

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benzoyl peroxide OTC

Benzac, PanOxyl

Benzoyl peroxide is a topical medicine that fights germs on your skin.

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betamethasone

Diprosone, Luxiq

Betamethasone dipropionate cream is a strong steroid medicine used on the skin.

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brodalumab

Siliq

Siliq is a medicine used to treat moderate to severe plaque psoriasis.

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calcipotriene

Dovonex

Calcipotriene and Betamethasone Dipropionate Ointment is a medicine that contains a vitamin D-like drug and a steroid.

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calcipotriene/betamethasone

Enstilar, Taclonex

Calcipotriene and Betamethasone Dipropionate Ointment is a medicine that combines a vitamin D-like drug and a steroid.

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clindamycin topical

Cleocin T, Clindagel

Clindamycin topical (Cleocin T) is a medicine you put on your skin to treat acne.

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clobetasol

Temovate, Clobex

Clobetasol ointment is a very strong steroid medicine used on the skin.

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crisaborole

Eucrisa

Eucrisa is a medicine used on the skin to treat eczema.

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cyclosporine

Neoral, Sandimmune, Restasis

Vevye eye drops contain cyclosporine.

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dapsone topical

Aczone

Aczone Gel is a topical medicine used to treat acne.

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desonide

DesOwen

Desonide cream is a low-strength steroid medicine.

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desoximetasone

Topicort

Desoximetasone is a steroid medicine that you put on your skin.

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erythromycin topical

Erygel

Erythromycin topical solution is a medicine that you put on your skin to treat acne.

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fluocinolone

Synalar, Derma-Smoothe

Fluocinolone is a topical steroid medicine.

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fluocinonide

Lidex, Vanos

Fluocinonide is a strong topical steroid medicine.

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fluorouracil topical

Efudex

Fluorouracil topical (Efudex) is a skin cream that treats certain skin conditions.

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guselkumab

Tremfya

Tremfya is a medicine that can help treat plaque psoriasis, psoriatic arthritis, ulcerative colitis, and Crohn's disease.

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halobetasol

Ultravate

Halobetasol Propionate Ointment is a strong steroid medicine used on the skin.

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hydrocortisone OTC

Cortef

Hydrocortisone cream helps relieve itching and skin problems.

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imiquimod

Aldara

Imiquimod cream helps your immune system fight certain skin problems.

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isotretinoin

Accutane, Absorica

Isotretinoin capsules are a strong medicine used to treat severe acne.

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ivermectin topical

Soolantra

Soolantra cream contains ivermectin and is used on the skin.

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ixekizumab

Taltz

Taltz is a medicine that can help treat plaque psoriasis, psoriatic arthritis, ankylosing spondylitis, and non-radiographic axial spondyloarthritis.

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ketoconazole OTC

Nizoral

Ketoconazole shampoo is an antifungal medicine.

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metronidazole topical

MetroGel

Metronidazole gel is a medicine that you put on your skin.

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minoxidil topical OTC

Rogaine

Minoxidil topical solution (Rogaine) is a medicine that helps regrow hair on your scalp.

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mometasone topical

Elocon

Mometasone Furoate Cream is a medicine that reduces skin inflammation and itching.

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mupirocin

Bactroban

Mupirocin cream is a topical antibiotic.

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permethrin OTC

Elimite, Nix

Permethrin cream rinse is a medicine that kills lice and their eggs.

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pimecrolimus

Elidel

Pimecrolimus cream (Elidel) is a medicine that can help with eczema.

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risankizumab

Skyrizi

Skyrizi is a medicine that can help reduce inflammation in your body.

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ruxolitinib topical

Opzelura

Opzelura is a cream that contains ruxolitinib.

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spironolactone (acne)

Aldactone

Spironolactone (Aldactone) is a medicine that helps remove extra fluid from your body and lower blood pressure.

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tacrolimus topical

Protopic

Tacrolimus extended-release capsules help prevent organ rejection in kidney transplant patients.

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tazarotene

Tazorac

Tazorac Cream contains tazarotene, a retinoid medicine.

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tretinoin

Retin-A

Tretinoin capsules help put acute promyelocytic leukemia (APL) into remission.

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triamcinolone OTC

Kenalog, Aristocort

Triamcinolone Acetonide Ointment is a steroid medicine that reduces inflammation and itching.

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ustekinumab

Stelara

Ustekinumab-aekn (Stelara) is a medicine that helps control inflammation in your body.

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Compare adapalene vs apremilast side-by-side →

Skin · large class with 1 active shortage

Skin is inventory #6 of 22 (largest of 2 at 41 drugs) ≠ FAERS-volume #13. Nationally Mental Health is inventory #1 of 22 (77 drugs) ≠ Pain Relief FAERS-volume #1 at inventory #3. 41 medicines tracked; 27 carry a NADAC generic flag; 1 in active FDA shortage.

Classes nearest Skin by inventory size