Sleep
Prescription and OTC sleep aids for insomnia, including benzodiazepine receptor agonists and melatonin receptor agonists.
10 medications in this category
eszopiclone
Lunesta
Eszopiclone (Lunesta) is a medicine that helps you fall asleep and stay asleep.
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lemborexant
Dayvigo
Dayvigo is a medicine that can help you fall asleep and stay asleep.
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melatonin
Melatonin
Melatonin is a hormone supplement that can help with sleep.
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ramelteon
Rozerem
Ramelteon (Rozerem) is a prescription medicine that can help you fall asleep faster.
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suvorexant
Belsomra
Belsomra is a prescription medicine used to treat insomnia.
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tasimelteon
Hetlioz
Tasimelteon (Hetlioz) is a medicine that helps people with Non-24-Hour Sleep-Wake Disorder (Non-24) sleep better.
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temazepam
Restoril
Temazepam is a medicine that helps you sleep.
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triazolam
Halcion
Triazolam (Halcion) is a medication used for the short-term treatment of insomnia.
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zaleplon
Sonata
Zaleplon (Sonata) is a medicine that helps you fall asleep faster.
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zolpidem
Ambien
Zolpidem (Ambien) is a medication that helps you fall asleep faster.
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Understanding the Sleep Category
The Sleep category currently lists 10 medications in this database, each drawn from FDA drug labels and grouped by therapeutic classification. Prescription and OTC sleep aids for insomnia, including benzodiazepine receptor agonists and melatonin receptor agonists. Clinical guidelines usually treat these medications as a reference set when weighing treatment options, switching strategies, or comparing safety profiles.
Within this category you'll find examples such as eszopiclone, lemborexant, melatonin, alongside 7 other entries. Each drug page links to the same underlying FDA data — labeled uses, adverse events reported to FAERS, documented interactions, warnings, and, where available, NADAC acquisition pricing from CMS. Over-the-counter and prescription options can sit in the same category but follow different regulatory pathways: OTC products have simplified labeling aimed at self-care, while prescription drugs include detailed monographs meant for clinicians. That distinction matters when comparing dosing, monitoring requirements, and contraindications.
Browsing a category is a research starting point, not a treatment recommendation. Effectiveness, tolerability, and cost for any individual patient depend on the specific condition, comorbidities, other medications, genetics, and insurance coverage — none of which can be inferred from a category list alone. FAERS report counts, recall history, and shortage status all evolve as new data is reported to the FDA, so the relative standing of drugs in this class can shift month to month. This page is for educational purposes only and is not medical advice — a licensed clinician is the right source for personalized guidance.
Read our methodology — how this data is sourced, computed, and verified.