Medication class
Sleep
Prescription and OTC sleep aids for insomnia, including benzodiazepine receptor agonists and melatonin receptor agonists.
Data updated 2026-05-15
- 10
- Medications
- 7
- With a generic
- 90%
- Avg generic savings
- 0
- In active shortage
Drug class assignments follow the FDA openFDA therapeutic classification, clinical details are drawn from FDA Structured Product Labeling via DailyMed, and unit-price comparisons use CMS National Average Drug Acquisition Cost data. See the full sources below.
Inventory versus report volume
Sleep is inventory #19 of 22 (largest of 2 at 10 drugs) ≠ FAERS-volume #20. Nationally Mental Health is inventory #1 of 22 (77 drugs) ≠ Pain Relief FAERS-volume #1 at inventory #3.
- #19
- inventory
- 10
- tracked drugs
- #20
- FAERS volume
- #1
- Pain Relief FAERS nationally
According to FDA FAERS report totals and openFDA class inventory compiled on /methodology. Class size is not the same map as report volume. This page is for informational purposes only and is not medical advice.
This class - generic availability cut
Exclusive DISTINCT-drug split of 10 medicines in Sleep. Orthogonal to inventory vs FAERS dual and to the NADAC cost ChartBar.
tasimelteon tops Sleep NADAC at $609.00/unit
Top 9 acquisition costs in this class (CMS NADAC)
- tasimelteon
tasimelteon
$609 per unit
- eszopiclone $23
eszopiclone
$23 per unit
- zolpidem $21
zolpidem
$21 per unit
- suvorexant $14
suvorexant
$14 per unit
- ramelteon $12
ramelteon
$12 per unit
- lemborexant $11
lemborexant
$11 per unit
- triazolam $0
triazolam
$0 per unit
- zaleplon $0
zaleplon
$0 per unit
- temazepam $0
temazepam
$0 per unit
What this shows tasimelteon is the costliest in this class at $609.00/unit; generics in the same class run a fraction of that.
Sleep · #20 inventory of 22 therapeutic classes
2 classes have fewer tracked drugs; percentile 9 among PlainMeds categories.
Sleep vs all classes by tracked-drug count
Where this class's inventory sits among every PlainMeds therapeutic category
10 20th of 22 higher than 2 of 22 classes
Classes, banded by tracked-drug inventory
Each bar is a band; taller bars hold more classes. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source PlainMeds openFDA therapeutic-class inventory · 2026-05-15
eszopiclone
Lunesta
Eszopiclone (Lunesta) is a medicine that helps you fall asleep and stay asleep.
View details →
lemborexant
Dayvigo
Dayvigo is a medicine that can help you fall asleep and stay asleep.
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melatonin OTC
Melatonin
Melatonin is a hormone supplement that can help with sleep.
View details →
ramelteon
Rozerem
Ramelteon (Rozerem) is a prescription medicine that can help you fall asleep faster.
View details →
suvorexant
Belsomra
Belsomra is a prescription medicine used to treat insomnia.
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tasimelteon
Hetlioz
Tasimelteon (Hetlioz) is a medicine that helps people with Non-24-Hour Sleep-Wake Disorder (Non-24) sleep better.
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temazepam
Restoril
Temazepam is a medicine that helps you sleep.
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triazolam
Halcion
Triazolam (Halcion) is a medication used for the short-term treatment of insomnia.
View details →
zaleplon
Sonata
Zaleplon (Sonata) is a medicine that helps you fall asleep faster.
View details →
zolpidem
Ambien
Zolpidem (Ambien) is a medication that helps you fall asleep faster.
View details →
Sleep · compact therapeutic class (10 tracked medicines)
Sleep is inventory #19 of 22 (largest of 2 at 10 drugs) ≠ FAERS-volume #20. Nationally Mental Health is inventory #1 of 22 (77 drugs) ≠ Pain Relief FAERS-volume #1 at inventory #3. 10 medicines tracked; 7 carry a NADAC generic flag.
Classes nearest Sleep by inventory size
Read our methodology - how this data is sourced, computed, and verified.