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ceftazidime

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Brand names: Fortaz

Third-Generation Cephalosporin Rx

Ceftazidime is an antibiotic medicine. It fights bacterial infections in your body.

Drug Shortage Alert

ceftazidime is currently listed as to be discontinued by the FDA. Affected manufacturer: Hospira, Inc., a Pfizer Company.

View all drug shortages →

Drug Pricing (NADAC)

Generic Price

$3.86/unit

Generic Available

Yes (3 manufacturers)

Pricing data from NADAC (CMS), effective December 18, 2024. Compare all drug costs →

What it does

Ceftazidime treats many kinds of infections caused by bacteria.

Common side effects

Pain or swelling where you got the shot, Rash, Itching

Key warnings

Ceftazidime can cause a type of diarrhea called pseudomembranous colitis.

How It Works

Ceftazidime belongs to a class of drugs called cephalosporins. It works by stopping bacteria from building their cell walls. This kills the bacteria and clears the infection.

How to Take It

A healthcare provider will give you ceftazidime through a vein or muscle. The usual adult dose is 1 gram every 8 to 12 hours. The exact dose and how often you get it depends on the type and severity of your infection. Your doctor will also consider how well your kidneys are working.

Pregnancy & Breastfeeding

Tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. It is not fully known if ceftazidime will harm your unborn baby or pass into breast milk.

Missed Dose

Since a healthcare provider gives you this medicine, you are not likely to miss a dose. Call your doctor if you think you missed a dose.

Storage

The medicine should be stored at room temperature (68°F to 77°F) and kept away from light.

Side Effects (from patient reports)

Based on 4,134 FDA adverse event reports.

Drug Ineffective
826
Off Label Use
657
Pyrexia
533
Septic Shock
335
Condition Aggravated
319
Neutropenia
317
Pneumonia
294
Acute Kidney Injury
293
Diarrhoea
292
Febrile Neutropenia
268

FDA Adverse Event Report Analysis

Detailed analysis of 7,404 reports from the FDA Adverse Event Reporting System (FAERS). Reports span 2004–2025.

Total Reports

7,404

Death-Related Reports

1,684

Hospitalization Reports

3,691

Top Indication

Product Used For Unknown Indication

Gender Distribution

Female 2,951 (43%)
Male 3,822 (56%)

Age Distribution

0–17 1,320
18–44 1,204
45–64 1,585
65–74 1,094
75+ 914

Most Reported Adverse Reactions (FAERS)

# Reaction Reports
1 DRUG INEFFECTIVE 827
2 OFF LABEL USE 657
3 PYREXIA 533
4 SEPTIC SHOCK 334
5 CONDITION AGGRAVATED 319
6 NEUTROPENIA 317
7 PNEUMONIA 294
8 ACUTE KIDNEY INJURY 293
9 DIARRHOEA 293
10 FEBRILE NEUTROPENIA 268
11 HYPOTENSION 265
12 SEPSIS 262
13 RESPIRATORY FAILURE 253
14 NAUSEA 247
15 DYSPNOEA 244

Reactions in Death Reports

DRUG INEFFECTIVE 324
SEPTIC SHOCK 219
PYREXIA 179
OFF LABEL USE 170
RESPIRATORY FAILURE 169
SEPSIS 159
MULTIPLE ORGAN DYSFUNCTION SYNDROME 152
DEATH 143
DIARRHOEA 112
NEUTROPENIA 109

Reactions in Hospitalization Reports

DRUG INEFFECTIVE 416
PYREXIA 356
OFF LABEL USE 251
SEPTIC SHOCK 232
DIARRHOEA 223
PNEUMONIA 219
NEUTROPENIA 204
FEBRILE NEUTROPENIA 200
RESPIRATORY FAILURE 193
ACUTE KIDNEY INJURY 192

Source: FDA FAERS (Adverse Event Reporting System) FDA FAERS (Adverse Event Reporting System) Reports are voluntary and do not establish causation

Serious Warnings

Ceftazidime can cause a type of diarrhea called pseudomembranous colitis. Tell your doctor right away if you have severe stomach pain or bloody diarrhea. This can happen during or after treatment.

Known Drug Interactions

Drug Interactions Nephrotoxicity has been reported following concomitant administration of cephalosporins with aminoglycoside antibacterial drugs or potent diuretics such as furosemide.

Mechanism: Combining these drugs can increase the chance of harming your kidneys.

What to do: Your doctor should monitor your kidney function tests regularly while you are taking this combination.

7.2 Drug/Laboratory Test Interactions The administration of ceftazidime may result in a false-positive reaction for glucose in the urine with certain methods.

Mechanism: This medicine can interfere with certain lab tests, making it look like there is sugar in your urine when there is not.

What to do: Inform your healthcare provider that you are taking this medication before you have any urine tests performed.

Common Questions

What if I am allergic to penicillin?
Tell your doctor if you are allergic to penicillin or other cephalosporin antibiotics. You should not take this medicine if you have had a bad allergic reaction to ceftazidime or any cephalosporin antibiotic in the past.
Can ceftazidime affect my kidneys?
Ceftazidime can sometimes affect your kidneys, especially if you are taking other medicines that can also affect them. Your doctor will monitor your kidney function.
Can ceftazidime interact with other medications I'm taking?
Yes, ceftazidime can interact with certain medications, such as aminoglycoside antibiotics and some diuretics. Be sure to tell your doctor about all the medications you are taking.
What are the symptoms of a hypersensitivity reaction?
Symptoms of a hypersensitivity reaction may include rash, itching, fever, angioedema, and anaphylaxis.
What if I experience seizures while taking ceftazidime?
Seizures have been reported with ceftazidime. Contact your doctor immediately if you experience seizures.
Does ceftazidime cause any changes in lab test results?
Yes, ceftazidime can cause changes in lab test results, such as elevated liver enzymes or changes in blood cell counts. Your doctor will monitor your lab results during treatment.
Can ceftazidime cause diarrhea?
Yes, diarrhea is a common side effect of ceftazidime. If you develop severe or persistent diarrhea, contact your doctor.
Is it safe to drive or operate machinery while taking ceftazidime?
Ceftazidime may cause dizziness or other central nervous system effects. Use caution when driving or operating machinery until you know how the medication affects you.
How long will I need to take ceftazidime?
The length of treatment with ceftazidime depends on the type and severity of your infection. Follow your doctor's instructions carefully.
What should I do if I experience any unusual side effects while taking ceftazidime?
If you experience any unusual or concerning side effects while taking ceftazidime, contact your doctor right away.
What are the common side effects of ceftazidime?
The most commonly reported side effects of ceftazidime include Pain or swelling where you got the shot, Rash, Itching, Fever, Diarrhea. Based on 4,134 FDA adverse event reports. Always consult your healthcare provider about potential side effects.
Does ceftazidime interact with other medications?
Yes, ceftazidime has 2 known drug interactions. Notable interactions include furosemide, ceftazidime/avibactam. Always inform your doctor about all medications you are taking.
What drug class is ceftazidime?
ceftazidime belongs to the Third-Generation Cephalosporin drug class. It requires a prescription (Rx). Ceftazidime treats many kinds of infections caused by bacteria.
Is ceftazidime safe during pregnancy?
Tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. It is not fully known if ceftazidime will harm your unborn baby or pass into breast milk. Always consult your healthcare provider before using any medication during pregnancy or breastfeeding.
Is ceftazidime currently in shortage?
Yes, ceftazidime is currently listed as to be discontinued by the FDA. Affected manufacturer: Hospira, Inc., a Pfizer Company. Visit the FDA Drug Shortages database for the latest updates.

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Related Health & Safety Data

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What the FDA Data Shows for ceftazidime

The FDA label for ceftazidime (sold under brand names such as Fortaz) classifies it as a prescription-only medication in the Third-Generation Cephalosporin class. Ceftazidime treats many kinds of infections caused by bacteria. Official labeling lists 8 commonly reported side effects, including Pain or swelling where you got the shot, Rash, Itching.

Post-market surveillance from the FDA Adverse Event Reporting System (FAERS) captures real-world experience. For this drug, FAERS contains 4,134 voluntary reports. The database also lists 2 documented drug interactions derived from FDA labeling, with the top-flagged interaction rated minor severity. NADAC pricing from CMS shows a generic unit cost of $3.86.

Report counts do not establish causation — a FAERS entry documents a temporal association, not proof that the drug produced the outcome. Widely prescribed medications naturally accumulate more reports than niche therapies, so raw totals must be interpreted alongside total exposure. Shortage status, recall history, and patent information further shape supply and switching decisions. This page summarizes public FDA data for educational purposes only and is not a substitute for professional medical advice — always consult a licensed healthcare provider before starting, stopping, or changing any medication.

Data Sources

Drug labeling: FDA Drug Labels (SPL/DailyMed). Adverse events: FDA Adverse Event Reporting System (FAERS). Pricing: CMS National Average Drug Acquisition Cost (NADAC). Shortage status: FDA Drug Shortages Database.

FAERS reports are voluntary and do not establish causation. Drug interactions are derived from FDA labeling and clinical references. Always consult a healthcare professional before making medication decisions.

Last updated: October 5, 2020

All federal data sources used on this page