tedizolid
Brand names: Sivextro
Tedizolid (Sivextro) is an antibiotic medicine. It fights certain bacteria that cause skin infections.
What it does
Tedizolid treats acute bacterial skin infections.
Common side effects
Nausea, Headache, Diarrhea
Key warnings
If you have a low white blood cell count (neutropenia), talk to your doctor.
How It Works
Tedizolid belongs to a class of drugs called oxazolidinones. It stops bacteria from growing by blocking their ability to make proteins. This helps your body fight off the infection.
How to Take It
For adults, the dose is 200 mg once a day for 6 days. You can take it as a pill or through an IV. You can take the pill with or without food. For children, the dose depends on their weight.
Pregnancy & Breastfeeding
Tedizolid may harm your unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. It is not known if tedizolid passes into breast milk, so talk to your doctor about breastfeeding.
Missed Dose
If you miss a dose, take it as soon as you remember. If it is close to your next dose, skip the missed dose and continue with your regular schedule.
Storage
Store tedizolid tablets and injection vials at room temperature, between 68°F and 77°F.
Side Effects (from patient reports)
Based on 517 FDA adverse event reports.
Serious Warnings
If you have a low white blood cell count (neutropenia), talk to your doctor. Tedizolid may not work as well. Diarrhea can happen while taking tedizolid or even months after. Tell your doctor right away if you get diarrhea.
Known Drug Interactions
If coadministration cannot be avoided, monitor for adverse reactions related to the concomitantly administered BCRP substrates, including rosuvastatin.
Mechanism: Tedizolid blocks a protein that helps clear rosuvastatin from your body, which can lead to higher levels of the drug.
What to do: Your doctor should monitor you for any side effects related to your cholesterol medication.
If possible, an interruption in the treatment of the co-administered BCRP substrate medicinal product should be considered during treatment with SIVEXTRO, especially for BCRP substrates with a narrow therapeutic index (e.g., methotrexate or topotecan).
Mechanism: Tedizolid stops a protein from moving methotrexate out of your body, which can cause the drug to build up to toxic levels.
What to do: Your doctor might have you stop taking methotrexate for a short time while you finish your antibiotic treatment.
Common Questions
What if I am allergic to tedizolid?
Can I take tedizolid with other medicines?
How long does it take for tedizolid to work?
What if my symptoms get worse?
Can tedizolid cause a yeast infection?
Is it safe to drink alcohol while taking tedizolid?
What should I do if I think I have a side effect?
Can I drive or operate machinery while taking tedizolid?
Do I need any special tests while taking tedizolid?
What if I still have questions about tedizolid?
What are the common side effects of tedizolid?
Does tedizolid interact with other medications?
What drug class is tedizolid?
Is tedizolid safe during pregnancy?
Related Medications in Oxazolidinone Antibiotic
Other drugs grouped near tedizolid — same-class peers and common alternatives.
amikacin
Amikin
Amikacin is an antibiotic medicine.
Compare with tedizolid →
amoxicillin
Amoxil
Amoxicillin and Clavulanate Potassium is a combination medicine used to fight bacterial infections.
Compare with tedizolid →
amoxicillin/clavulanate
Augmentin
Augmentin is a combination of two medicines, amoxicillin and clavulanate.
Compare with tedizolid →
ampicillin/sulbactam
Unasyn
Unasyn is a combination of two antibiotics that fights bacteria in your body.
Compare with tedizolid →
azithromycin
Zithromax, Z-Pack
Azithromycin is an antibiotic that fights bacteria.
Compare with tedizolid →
Medication Guides
Understanding Drug Interactions
How CYP450 enzymes, inhibitors, and inducers affect your medications
Generic vs Brand Name Drugs
FDA requirements, cost savings, and when the difference matters
Narrow Therapeutic Index Drugs
Why some drugs demand precise dosing and monitoring
Common Drug Interactions
Dangerous medication combinations and how to protect yourself
Related Health & Safety Data
🩺 Find a Doctor
Search prescribers for Oxazolidinone Antibiotic
🏨 Hospital Quality
CMS hospital ratings, safety scores & patient outcomes
💊 Supplement Data
NIH DSLD — check supplement ingredients & label claims
🍽️ Food Safety Alerts
FDA recalls, inspections & outbreak investigations
⚠️ Product Recalls
FDA, CPSC & NHTSA recall search
💉 Procedure Costs
Medicare procedure pricing for 9,297 procedures
Save on tedizolid
Compare prices and find discounts at pharmacies near you. Free coupons can save up to 80% on prescriptions.
Disclosure: This link may earn us a commission at no extra cost to you. See our terms.
What the FDA Data Shows for tedizolid
The FDA label for tedizolid (sold under brand names such as Sivextro) classifies it as a prescription-only medication in the Oxazolidinone Antibiotic class. Tedizolid treats acute bacterial skin infections. Official labeling lists 6 commonly reported side effects, including Nausea, Headache, Diarrhea.
Post-market surveillance from the FDA Adverse Event Reporting System (FAERS) captures real-world experience. For this drug, FAERS contains 517 voluntary reports. The database also lists 2 documented drug interactions derived from FDA labeling, with the top-flagged interaction rated minor severity. Acquisition-cost data is surveyed weekly by CMS and updated as manufacturers report changes.
Report counts do not establish causation — a FAERS entry documents a temporal association, not proof that the drug produced the outcome. Widely prescribed medications naturally accumulate more reports than niche therapies, so raw totals must be interpreted alongside total exposure. Shortage status, recall history, and patent information further shape supply and switching decisions. This page summarizes public FDA data for educational purposes only and is not a substitute for professional medical advice — always consult a licensed healthcare provider before starting, stopping, or changing any medication.
Data Sources
Drug labeling: FDA Drug Labels (SPL/DailyMed). Adverse events: FDA Adverse Event Reporting System (FAERS).
FAERS reports are voluntary and do not establish causation. Drug interactions are derived from FDA labeling and clinical references. Always consult a healthcare professional before making medication decisions.
Last updated: April 4, 2025
Read our methodology — how this data is sourced, computed, and verified.
All federal data sources used on this page
- FDA Orange Book — approved drug products with therapeutic equivalence. accessdata.fda.gov/cder/ob
- FDA DailyMed — NIH-hosted drug labeling for FDA-approved meds. dailymed.nlm.nih.gov
- FDA Adverse Event Reporting System (FAERS) — post-marketing safety surveillance. fda.gov/drugs/faers
- NLM RxNorm — standardized clinical drug nomenclature. nlm.nih.gov/research/umls/rxnorm
- CMS Medicare Part B Drug Average Sales Price Files — federal drug pricing data. cms.gov/medicare/part-b-drugs/asp
- FDA Drug Shortages Database — current and resolved drug shortage tracking. accessdata.fda.gov/drugshortages