Side effects across medicines
Medicines whose labels list loss of appetite
774 medicines have an FDA label that names loss of appetite in its boxed warning, warnings, adverse reactions, trial table, patient leaflet or Drug Facts “stop use” warning (of the labels PlainMeds reads: each medicine's quoted label and up to eight more, by route and wording). Among them, the most FAERS reports of loss of appetite name ergocalciferol (9,861), omeprazole (8,786) and furosemide (8,552), through July 30, 2026. A label lists what its studies and reports found, and a report does not show that a medicine caused the event.
Check it at the source: the FDA FAERS public dashboard; FDA labels on DailyMed.
Which medicines' labels list loss of appetite?
Ordered by where the label names it, the boxed warning first, then by FAERS reports. The first 150 of the 774 are below; every other one is on its medicine record. A medicine whose own indications name it, because it treats it, is not counted.
| Medicine | Where a label names it | FAERS reports of loss of appetite |
|---|---|---|
| Valproic acid | boxed warning (intravenous label) | 405 |
| Digoxin | warnings and precautions (intramuscular/ | 1,771 |
| Morphine | warnings and precautions (intravenous label) | 1,706 |
| Hydromorphone | warnings and precautions (intramuscular/ | 1,365 |
| Buprenorphine | warnings (intramuscular/ | 846 |
| Acetaminophen and codeine | precautions | 748 |
| Lovastatin | precautions | 528 |
| Acetaminophen and hydrocodone | precautions | 525 |
| Acetaminophen and oxycodone | precautions | 509 |
| Rivastigmine | warnings and precautions (transdermal label) | 505 |
| Methadone | precautions (intramuscular/ | 452 |
| Buprenorphine and naloxone | warnings and precautions (buccal/ | 442 |
| Rifampin | precautions | 223 |
| Zonisamide | precautions | 223 |
| Acetazolamide | precautions | none in the top 1,000 |
| Aspirin and oxycodone | precautions | none in the top 1,000 |
| Auranofin | precautions | none in the top 1,000 |
| Butorphanol | precautions (nasal label) | none in the top 1,000 |
| Cysteamine | warnings and precautions (oral label) | none in the top 1,000 |
| Disulfiram | precautions | none in the top 1,000 |
| Dofetilide | precautions | none in the top 1,000 |
| Doxercalciferol | warnings and precautions (oral label) | none in the top 1,000 |
| Ethacrynic acid | precautions | none in the top 1,000 |
| Hydrocodone and ibuprofen | precautions | none in the top 1,000 |
| Levorphanol | precautions | none in the top 1,000 |
| Methazolamide | precautions | none in the top 1,000 |
| Nalbuphine | warnings (intramuscular/ | none in the top 1,000 |
| Ofloxacin | precautions (oral label) | none in the top 1,000 |
| Paricalcitol | warnings and precautions (intravenous label) | none in the top 1,000 |
| Procainamide | precautions | none in the top 1,000 |
| Propylthiouracil | precautions | none in the top 1,000 |
| Pyrimethamine | precautions | none in the top 1,000 |
| Tolcapone | precautions | none in the top 1,000 |
| Ergocalciferol | adverse reactions | 9,861 |
| Omeprazole | adverse reactions | 8,786 |
| Furosemide | adverse reactions | 8,552 |
| Methotrexate | adverse reactions | 6,769 |
| Gabapentin | adverse reactions | 6,583 |
| Folic acid | adverse reactions | 6,269 |
| Lenalidomide | adverse reactions | 6,093 |
| Amlodipine | adverse reactions | 5,982 |
| Exenatide | adverse reactions | 5,643 |
| Semaglutide | adverse reactions (oral label) | 4,905 |
| Oxycodone | adverse reactions | 4,825 |
| Cabozantinib | adverse reactions | 4,620 |
| Rituximab | adverse reactions | 4,203 |
| Apremilast | adverse reactions | 3,896 |
| Alprazolam | adverse reactions | 3,881 |
| Quetiapine | adverse reactions | 3,507 |
| Diphenhydramine | adverse reactions | 3,492 |
| Palbociclib | adverse reactions | 3,488 |
| Treprostinil | adverse reactions | 3,477 |
| Bevacizumab | adverse reactions | 3,461 |
| Leflunomide | adverse reactions | 3,443 |
| Enzalutamide | adverse reactions | 3,408 |
| Ramipril | adverse reactions | 3,365 |
| Pembrolizumab | adverse reactions | 3,305 |
| Pirfenidone | adverse reactions | 3,272 |
| Ribavirin | adverse reactions | 3,272 |
| Capecitabine | adverse reactions | 3,269 |
| Dulaglutide | adverse reactions | 3,255 |
| Celecoxib | adverse reactions | 3,209 |
| Lenvatinib | adverse reactions | 3,112 |
| Tirzepatide | adverse reactions | 3,087 |
| Nintedanib | adverse reactions | 3,085 |
| Clonazepam | adverse reactions | 3,027 |
| Allopurinol | adverse reactions | 3,012 |
| Hydrochlorothiazide | adverse reactions | 2,967 |
| Sulfasalazine | adverse reactions | 2,940 |
| Peginterferon alfa 2a | adverse reactions | 2,918 |
| Nivolumab | adverse reactions | 2,901 |
| Carboplatin | adverse reactions | 2,895 |
| Hydroxychloroquine | adverse reactions | 2,825 |
| Escitalopram | adverse reactions | 2,823 |
| Zolpidem | adverse reactions | 2,726 |
| Mirtazapine | adverse reactions | 2,475 |
| Citalopram | adverse reactions | 2,435 |
| Denosumab | adverse reactions | 2,428 |
| Letrozole | adverse reactions | 2,387 |
| Mycophenolate mofetil | adverse reactions | 2,382 |
| Sunitinib | adverse reactions | 2,316 |
| Fluoxetine | adverse reactions | 2,313 |
| Venlafaxine | adverse reactions | 2,303 |
| Sertraline | adverse reactions | 2,295 |
| Oxaliplatin | adverse reactions | 2,145 |
| Everolimus | adverse reactions | 2,108 |
| Liraglutide | adverse reactions | 2,108 |
| Topiramate | adverse reactions | 2,072 |
| Levetiracetam | adverse reactions | 2,056 |
| Diazepam | adverse reactions (rectal label) | 2,031 |
| Doxycycline | adverse reactions | 2,006 |
| Lamotrigine | adverse reactions | 1,913 |
| Sulfamethoxazole and trimethoprim | adverse reactions | 1,904 |
| Cisplatin | adverse reactions | 1,884 |
| Niraparib | adverse reactions | 1,881 |
| Ciprofloxacin | adverse reactions | 1,874 |
| Docetaxel | adverse reactions | 1,777 |
| Vedolizumab | adverse reactions | 1,732 |
| Methylphenidate | adverse reactions | 1,656 |
| Bupropion | adverse reactions | 1,609 |
| Trastuzumab | adverse reactions | 1,598 |
| Fentanyl | adverse reactions (transdermal label) | 1,497 |
| Fulvestrant | adverse reactions | 1,456 |
| Sorafenib | adverse reactions | 1,449 |
| Pazopanib | adverse reactions | 1,438 |
| Bortezomib | adverse reactions | 1,431 |
| Selexipag | adverse reactions | 1,412 |
| Ribociclib | adverse reactions | 1,405 |
| Selinexor | adverse reactions | 1,384 |
| Duloxetine | adverse reactions | 1,364 |
| Tramadol | adverse reactions | 1,337 |
| Zoledronic acid | adverse reactions | 1,322 |
| Tacrolimus | adverse reactions | 1,270 |
| Donepezil | adverse reactions | 1,229 |
| Metronidazole | adverse reactions | 1,167 |
| Anastrozole | adverse reactions | 1,157 |
| Doxorubicin | adverse reactions | 1,137 |
| Ibrutinib | adverse reactions | 1,126 |
| Enalapril | adverse reactions | 1,125 |
| Gemcitabine | adverse reactions | 1,119 |
| Ipilimumab | adverse reactions | 1,117 |
| Atezolizumab | adverse reactions | 1,110 |
| Aprepitant | adverse reactions | 1,096 |
| Diltiazem | adverse reactions | 1,095 |
| Aripiprazole | adverse reactions | 1,093 |
| Regorafenib | adverse reactions | 1,091 |
| Axitinib | adverse reactions | 1,087 |
| Baclofen | adverse reactions | 1,073 |
| Pemetrexed | adverse reactions | 1,065 |
| Levofloxacin | adverse reactions | 1,043 |
| Risperidone | adverse reactions | 1,042 |
| Pomalidomide | adverse reactions | 1,013 |
| Varenicline | adverse reactions | 995 |
| Clonidine | adverse reactions | 992 |
| Atomoxetine | adverse reactions | 987 |
| Leuprolide | adverse reactions | 979 |
| Cyclosporine | adverse reactions | 966 |
| Sodium oxybate | adverse reactions | 962 |
| Cyclobenzaprine | adverse reactions | 958 |
| Lisdexamfetamine | adverse reactions | 947 |
| Exemestane | adverse reactions | 894 |
| Temazepam | adverse reactions | 891 |
| Azithromycin | adverse reactions | 889 |
| Etoposide | adverse reactions | 869 |
| Cetuximab | adverse reactions | 867 |
| Venetoclax | adverse reactions | 851 |
| Cinacalcet | adverse reactions | 828 |
| Budesonide | adverse reactions | 819 |
| Naltrexone | adverse reactions | 819 |
| Paroxetine | adverse reactions | 819 |
Source: FDA drug labels via openFDA, read October 8, 2026; FAERS via openFDA, reports through July 30, 2026
Which of them have the most loss of appetite reports in FAERS?
Counts follow how widely a medicine is used and watched, and they are not a measure of how risky it is.
Source: FDA Adverse Event Reporting System (FAERS) via openFDA, reports through July 30, 2026; MedDRA preferred term “Decreased Appetite”
What next?
- Side effects across medicines
- every reaction on PlainMeds
- Report a side effect to the FDA
- MedWatch