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Prescription medicine

Rivastigmine Brand names: Exelon

Rivastigmine (Exelon) is a prescription medicine with an FDA approval on record since 2000. FDA's NDC Directory lists it from 18 generic labelers, and pharmacies paid $0.164 per rivastigmine 1.5 mg capsule in the October 7, 2026 NADAC survey.

  • Generic listed
  • A presentation discontinued

Check it at the source: the rivastigmine FDA label on DailyMed (effective June 19, 2024, Aurobindo Pharma Limited); the NDA 20823 record on Drugs@FDA; every rivastigmine label on DailyMed.

Highlights of the record

FDA label of June 19, 2024; NDC Directory, Drugs@FDA and Orange Book, October 8, 2026; NADAC October 7, 2026

Used for

From the label: indications and usage

Rivastigmine tartrate capsules are an acetylcholinesterase inhibitor indicated for treatment of: Mild-to-moderate dementia of the Alzheimer’s type (AD) ( 1.1 ) Mild-to-moderate dementia associated with Parkinson’s disease (PD) ( 1.2 ) 1.1 Alzheimer’s Disease Rivastigmine tartrate capsules are indicated for the treatment of mild-to-moderate dementia of the Alzheimer's type (AD).

Forms and strengths

  • 1.5 mg
  • 3 mg
  • 4.5 mg
  • 6 mg
  • 4.6 mg/24h
  • 9.5 mg/24h
  • 13.3 mg/24h

Capsule; extended-release patch; patch.

On the market

Earliest approval on file
April 21, 2000 Exelon, Novartis; Drugs@FDA’s file, where older or withdrawn approvals can be missing
Generic approvals
16 first October 22, 2007; 13 with a marketed status in Drugs@FDA
Labelers listed (NDC)
20 of which 18 under generic applications, 2 under brand applications, repackagers included

Supply and safety

Pharmacy cost (NADAC)
$0.164 per capsule Rivastigmine 1.5 mg capsule
Shortage (FDA)
None current 1 past records
Recalls by its makers (FDA)
2 since 2015 0 Class I among all firms' recalls; latest March 6, 2017
FAERS reports
19,159 through July 30, 2026

What is rivastigmine used for?

From the label: indications and usage

Rivastigmine tartrate capsules are an acetylcholinesterase inhibitor indicated for treatment of: Mild-to-moderate dementia of the Alzheimer’s type (AD) ( 1.1 ) Mild-to-moderate dementia associated with Parkinson’s disease (PD) ( 1.2 ) 1.1 Alzheimer’s Disease Rivastigmine tartrate capsules are indicated for the treatment of mild-to-moderate dementia of the Alzheimer's type (AD). 1.2 Parkinson’s Disease Dementia Rivastigmine tartrate capsules are indicated for the treatment of mild-to-moderate dementia associated with Parkinson’s disease (PD).

Conditions named in the indications of rivastigmine's FDA labels, with every medicine labeled for each:

FDA pharmacologic class: Cholinesterase Inhibitor.

Source: FDA drug label (Rivastigmine Tartrate), Aurobindo Pharma Limited, effective June 19, 2024 (SPL set c246a0e5-1e77-41ee-a7b3-384f21f2f2e0), via openFDA; the full label on DailyMed

What does the patient leaflet for rivastigmine say first?

The FDA-approved Medication Guide or Patient Information that comes with the medicine, in its own words.

From the patient leaflet: What should I avoid while using EXELON PATCH?

Do not touch your eyes after you touch the EXELON PATCH. In case of accidental contact with your eyes or if your eyes become red after handling the patch, rinse immediately with plenty of water and seek medical advice if symptoms do not resolve. • EXELON PATCH can cause drowsiness, dizziness, weakness, or fainting. Do not drive, operate heavy machinery, or do other dangerous activities until you know how EXELON PATCH affects you. • Avoid exposure to heat sources, such as excessive sunlight, saunas, or sunrooms for long periods of time.

From the patient leaflet: How should I store EXELON PATCH?

Store EXELON PATCH between 68°F to 77°F (20°C to 25°C). • Keep EXELON PATCH in the sealed pouch until ready to use. Keep EXELON PATCH and all medicines out of the reach of children.

Source: FDA drug label (Exelon), Sandoz Inc, effective May 8, 2024 (SPL set b6ed6d15-116d-4596-92ce-3414574d7ba0), via openFDA; the full label on DailyMed

Is there a generic for rivastigmine (Exelon)?

The FDA approved the first generic rivastigmine on October 22, 2007. 16 generic applications are approved; 13 of them carry a current (not discontinued) marketing status in Drugs@FDA; that status is not evidence that the generic is on sale. Drugs@FDA also holds 1 tentative approval: the FDA found the generic approvable, but patents or exclusivity keep it from final approval for now.

FDA's NDC Directory lists rivastigmine from 18 labelers under a generic (ANDA) application and from 2 brand labelers. A listing means the company has registered the product for sale; it does not show that every pharmacy stocks it.

  • 2000 earliest approval on file
  • 2007 first generic approved
  • red ticks recalls

Source: Drugs@FDA, FDA NDC Directory and the Orange Book (openFDA bulk files, October 8, 2026)

What do pharmacies pay for rivastigmine (Exelon)?

In CMS's NADAC survey of October 7, 2026, pharmacies paid $0.164 per Rivastigmine 1.5 mg capsule, down 11% from $0.184 on October 8, 2025. Prices per unit in the table differ many-fold by strength, form and brand, so compare like with like. The chart's scale runs from the lowest to the highest price shown, not from zero. NADAC is what retail pharmacies paid their wholesalers, per unit, in CMS's monthly survey; what a patient pays depends on insurance and the pharmacy.

  • Rivastigmine 1.5 mg capsule (generic)
  • Exelon 9.5 mg/24hr patch (brand)
$21.97
$0.146
January 2024October 2026
NADAC per unit, October 7, 2026
Strength and formBrand or genericPharmacy cost30 tablets, or one pen or vial12-month change
Rivastigmine 1.5 mg capsuleGeneric$0.164 per capsule$4.93-11%
Rivastigmine 13.3 mg/24hr ptchGeneric$1.80 per unitn/a-5%
Rivastigmine 3 mg capsuleGeneric$0.146 per capsule$4.37-20%
Rivastigmine 4.5 mg capsuleGeneric$0.174 per capsule$5.23-11%
Rivastigmine 4.6 mg/24hr patchGeneric$1.75 per patchn/a-4%
Rivastigmine 6 mg capsuleGeneric$0.156 per capsule$4.69-29%
Rivastigmine 9.5 mg/24hr patchGeneric$1.78 per patchn/a-4%
Exelon 4.6 mg/24hr patchBrand$21.87 per patch many times the lowest per-tablet cost; NADAC records the price, not whyn/a-0.3%
Exelon 9.5 mg/24hr patchBrand$21.81 per patch many times the lowest per-tablet cost; NADAC records the price, not whyn/a-0.5%

Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price

Is rivastigmine in shortage?

No rivastigmine presentation is listed as in shortage in the FDA Drug Shortage Database (read October 8, 2026); its 1 record is all marked to be discontinued, the latest updated September 18, 2026. ASHP keeps a separate shortage list, which can differ.

PresentationCompanyStatusUpdated
Rivastigmine, Film, Extended Release, 4.6 mg/24 h (NDC 0378-9070-93)Mylan Pharmaceuticals Inc., a Viatris CompanyTo Be DiscontinuedSeptember 18, 2026

Every rivastigmine presentation in the FDA shortage database

Source: FDA Drug Shortage Database via openFDA, updated October 8, 2026

Has rivastigmine been recalled?

The FDA's Enforcement Report lists 2 recalls naming rivastigmine since 2015: 0 Class I (the most serious), 1 Class II, 1 Class III; 0 still ongoing. A recall names products and lots, not every product of the medicine.

StartedClassCompanyReason
March 6, 2017Class IIIDr. Reddy's Laboratories, Inc.Cross-contamination with other products -Related Substances test for Rivastigmine Tartrate Capsules USP, 1.5 mg showed a peak for Ranitidine.
August 3, 2015Class IIDr. Reddy's Laboratories, Inc.Failed Dissolution Specifications

Source: FDA Enforcement Report (drug recalls) via openFDA, through October 8, 2026

What does the rivastigmine label say about other medicines?

The rivastigmine label names 4 other medicines in its interaction, contraindication or warning sections. The sentences are the labels' own; a label lists what its studies and reports found, not every interaction.

Medicine namedSectionWhat the label says
Atenololdrug interactionsAdditive bradycardic effects resulting in syncope may occur when rivastigmine tartrate is used concomitantly with beta-blockers, especially cardioselective beta-blockers (including atenolol).
Metoclopramidedrug interactionsDRUG INTERACTIONS Concomitant use with metoclopramide, beta-blockers, or cholinomimetic and anticholinergic drugs is not recommended
Oxybutynindrug interactionsRivastigmine tartrate may increase the cholinergic effects of other cholinomimetic medications and may also interfere with the activity of anticholinergic medications (e.g., oxybutynin, tolterodine).
Tolterodinedrug interactionsRivastigmine tartrate may increase the cholinergic effects of other cholinomimetic medications and may also interfere with the activity of anticholinergic medications (e.g., oxybutynin, tolterodine).

Check rivastigmine against other medicines

Source: FDA drug label (Rivastigmine Tartrate), Aurobindo Pharma Limited, effective June 19, 2024 (SPL set c246a0e5-1e77-41ee-a7b3-384f21f2f2e0), via openFDA; the full label on DailyMed

What do FAERS reports show for rivastigmine?

The FDA Adverse Event Reporting System holds 19,159 reports that list rivastigmine among the medicines taken, through July 30, 2026, each a report of something that happened, not proof the medicine caused it; 4,813 are coded as a death and 6,944 as a hospital stay. Counts follow how widely a medicine is used and watched, and they are not a measure of how risky it is.

Reports received each year

The most reported reactions

  • Death (an outcome recorded in the report)2,349
  • Fall1,792
  • Hallucination (named in the label)1,476
  • Confusional State1,349
  • Drug Ineffective (a use or a product term, not a reaction)974
  • Vomiting (named in the label)933
  • Nausea (named in the label)877
  • Dizziness (named in the label)827

Side effects: the label's list and every FAERS reaction

Source: FDA Adverse Event Reporting System (FAERS) via openFDA, reports through July 30, 2026

What else is labeled for the same conditions as rivastigmine?

4 other medicines are given the same way (oral) and in the same FDA class as rivastigmine or labeled mainly for the same use (alzheimer's disease), the same class first. Alzheimer's disease lists all 7 medicines labeled for it, by any route. They are listed as records, not as substitutes: whether one can replace another is a prescriber's decision.

MedicineShared indicationGeneric labelers (oral)Pharmacy costShortage
DonepezilAlzheimer's disease31 labelers$0.0484 per tablet 10 mg tabletNo current entry
GalantamineAlzheimer's disease9 labelers$0.294 per tablet 4 mg tabletNo current entry
Donepezil and memantineAlzheimer's disease5 labelers$8.44 per unit 28-10 mgA presentation being discontinued
MemantineAlzheimer's disease38 labelers$0.063 per tablet 10 mg tabletNo current entry

Every medicine labeled for the same conditions as rivastigmine

Source: FDA drug labels (indications), NDC Directory, NADAC of October 7, 2026, FDA shortages (October 8, 2026)

How does rivastigmine compare with medicines for the same use?

3 side-by-side pages set rivastigmine beside a medicine whose label shares a use: approvals, generics, pharmacy cost, warnings and supply.

What next?

Alternatives to rivastigmine
4 medicines for the same use
Other cholinesterase inhibitors
the pharmacologic class, with prices and generics
Rivastigmine side effects
the label's list beside FAERS reports
Rivastigmine shortage record
every presentation, company and date
Check an interaction
what two or more labels say about each other