Side effects across medicines

Medicines whose labels list anaphylactic reaction

275 medicines have an FDA label that names anaphylactic reaction in its boxed warning, warnings, adverse reactions, trial table, patient leaflet or Drug Facts “stop use” warning (of the labels PlainMeds reads: each medicine's quoted label and up to eight more, by route and wording). Among them, the most FAERS reports of anaphylactic reaction name rocuronium (1,279), diclofenac (1,210) and amoxicillin (1,101), through July 30, 2026. A label lists what its studies and reports found, and a report does not show that a medicine caused the event.

Check it at the source: the FDA FAERS public dashboard; FDA labels on DailyMed.

Which medicines' labels list anaphylactic reaction?

Ordered by where the label names it, the boxed warning first, then by FAERS reports. The first 150 of the 275 are below; every other one is on its medicine record. A medicine whose own indications name it, because it treats it, is not counted.

Medicine	Where a label names it	FAERS reports of anaphylactic reaction
Diclofenac	warnings (oral label)	1,210
Epinephrine and lidocaine	warnings and precautions (submucosal label)	874
Ciprofloxacin	warnings and precautions (intravenous label)	548
Cyclosporine	warnings (intravenous/oral label)	527
Bisoprolol	precautions	438
Bevacizumab	warnings and precautions (intravascular label)	316
Levofloxacin	warnings and precautions (intravenous label)	272
Tacrolimus	warnings and precautions (intravenous/oral label)	272
Propranolol	precautions (intravenous label)	264
Moxifloxacin	warnings and precautions (intravenous label)	243
Etoposide	precautions	235
Ipratropium	warnings and precautions (respiratory (inhalation) label)	223
Sumatriptan	warnings and precautions (nasal label)	184
Cromolyn	warnings (oral label)	123
Cyanocobalamin	warnings and precautions (nasal label)	116
Medroxyprogesterone	warnings and precautions (intramuscular label)	116
Succinylcholine	warnings and precautions (intramuscular/intravenous/parenteral label)	112
Estrogens conjugated	warnings (intramuscular/intravenous label)	104
Alteplase	warnings and precautions	100
Leucovorin	warnings and precautions (oral label)	97
Vecuronium	precautions	79
Atracurium	precautions	66
Indomethacin	warnings and precautions (rectal label)	59
Clindamycin	warnings (intramuscular/intravenous label)	47
Isatuximab	warnings and precautions (subcutaneous label)	36
Flurbiprofen	warnings and precautions (oral label)	26
Labetalol	precautions (intravenous label)	26
Ofloxacin	warnings (oral label)	26
Betamethasone	warnings (intra-articular/intralesional/intramuscular label)	25
Mesna	warnings and precautions (oral label)	21
Acebutolol	precautions	none in the top 1,000
Acetaminophen and ibuprofen	warnings and precautions (intravenous label)	none in the top 1,000
Betaxolol	precautions	none in the top 1,000
Bisoprolol and hydrochlorothiazide	precautions	none in the top 1,000
Cerliponase alfa	warnings and precautions	none in the top 1,000
Cetrorelix	precautions	none in the top 1,000
Daratumumab	warnings and precautions	none in the top 1,000
Diclofenac and menthol and methyl salicylate	warnings and precautions	none in the top 1,000
Hyaluronidase and trastuzumab	warnings and precautions	none in the top 1,000
Ibandronate	warnings and precautions (intravenous label)	none in the top 1,000
Levobunolol	precautions	none in the top 1,000
Lidocaine and prilocaine	warnings and precautions (periodontal label)	none in the top 1,000
Pindolol	precautions	none in the top 1,000
Polidocanol	warnings and precautions (intravenous label)	none in the top 1,000
Technetium tc 99m sulfur colloid	warnings and precautions	none in the top 1,000
Tenecteplase	warnings and precautions	none in the top 1,000
Tigecycline	warnings and precautions (intravenous/parenteral label)	none in the top 1,000
Rocuronium	adverse reactions	1,279
Amoxicillin	adverse reactions	1,101
Leflunomide	adverse reactions	1,057
Lidocaine	adverse reactions	966
Ondansetron	adverse reactions	930
Carboplatin	adverse reactions	799
Celecoxib	adverse reactions	782
Esomeprazole	adverse reactions (intravenous label)	762
Budesonide and formoterol	adverse reactions	536
Cetuximab	adverse reactions	509
Glatiramer	adverse reactions	433
Oxycodone	adverse reactions	361
Budesonide	adverse reactions (oral label)	357
Hydrochlorothiazide	adverse reactions	345
Losartan	adverse reactions	337
Pegvaliase	adverse reactions	327
Fluticasone and salmeterol	adverse reactions	312
Sugammadex	adverse reactions	308
Carvedilol	adverse reactions	303
Cefuroxime	adverse reactions	300
Hydromorphone	adverse reactions (intramuscular/intravenous/subcutaneous label)	278
Clarithromycin	adverse reactions	264
Spironolactone	adverse reactions	261
Meloxicam	adverse reactions	235
Pegaspargase	adverse reactions	235
Sevoflurane	adverse reactions	235
Amoxicillin and clavulanate	adverse reactions	230
Aprepitant	adverse reactions	230
Irbesartan	adverse reactions	224
Fluconazole	adverse reactions	214
Estradiol	adverse reactions (oral label)	208
Apixaban	adverse reactions	199
Rivaroxaban	adverse reactions	166
Denosumab	adverse reactions	154
Remifentanil	adverse reactions	150
Gadobutrol	adverse reactions	139
Nifedipine	adverse reactions	138
Warfarin	adverse reactions	134
Risperidone	adverse reactions	118
Ampicillin	adverse reactions	100
Calaspargase	adverse reactions	98
Brentuximab vedotin	adverse reactions	92
Olmesartan	adverse reactions	90
Upadacitinib	adverse reactions	89
Piroxicam	adverse reactions	87
Gatifloxacin	adverse reactions	85
Tizanidine	adverse reactions	85
Anakinra	adverse reactions	84
Dulaglutide	adverse reactions	83
Indapamide	adverse reactions	83
Dapagliflozin	adverse reactions	81
Penicillin g	adverse reactions	81
Formoterol and mometasone	adverse reactions	79
Liraglutide	adverse reactions	79
Methocarbamol	adverse reactions	79
Golimumab	adverse reactions	77
Oxcarbazepine	adverse reactions	77
Lisdexamfetamine	adverse reactions	76
Misoprostol	adverse reactions	68
Progesterone	adverse reactions	68
Oxytocin	adverse reactions	66
Exenatide	adverse reactions	64
Icatibant	adverse reactions	62
Sacubitril and valsartan	adverse reactions	62
Telmisartan	adverse reactions	58
Tobramycin	adverse reactions	52
Haloperidol	adverse reactions (intramuscular label)	51
Letrozole	adverse reactions	51
Sucralfate	adverse reactions	50
Dabigatran	adverse reactions	46
Formoterol	adverse reactions	46
Fremanezumab	adverse reactions	46
Phytonadione	adverse reactions	45
Diclofenac and misoprostol	adverse reactions	44
Oxybutynin	adverse reactions	44
Ifosfamide	adverse reactions	43
Zoledronic acid	adverse reactions	43
Thiamine	adverse reactions	42
Baloxavir marboxil	adverse reactions	40
Meclizine	adverse reactions	39
Canakinumab	adverse reactions	37
Idursulfase	adverse reactions	36
Teriparatide	adverse reactions	36
Conestat alfa	adverse reactions	35
Paliperidone	adverse reactions	33
Salmeterol	adverse reactions	33
Drospirenone and ethinyl estradiol	adverse reactions	30
Somatropin	adverse reactions	29
Tuberculin purified protein derivative	adverse reactions	29
Hydrochlorothiazide and losartan	adverse reactions	28
Deferasirox	adverse reactions	27
Febuxostat	adverse reactions	27
Remdesivir	adverse reactions	26
Dalbavancin	adverse reactions	25
Hydrochlorothiazide and lisinopril	adverse reactions	25
Abaloparatide	adverse reactions	24
Mefenamic acid	adverse reactions	23
Vinorelbine	adverse reactions	22
Fondaparinux	adverse reactions	21
Dextroamphetamine	adverse reactions (transdermal label)	20
Valganciclovir	adverse reactions	20
Abiraterone	adverse reactions	none in the top 1,000
Abiraterone and niraparib	adverse reactions	none in the top 1,000

Source: FDA drug labels via openFDA, read October 8, 2026; FAERS via openFDA, reports through July 30, 2026

Which of them have the most anaphylactic reaction reports in FAERS?

Counts follow how widely a medicine is used and watched, and they are not a measure of how risky it is.

Source: FDA Adverse Event Reporting System (FAERS) via openFDA, reports through July 30, 2026; MedDRA preferred term “Anaphylactic Reaction”

What next?

Side effects across medicines: every reaction on PlainMeds
Report a side effect to the FDA: MedWatch