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formoterol

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Brand names: Foradil, Perforomist

Long-Acting Beta-2 Agonist (LABA) Rx

Formoterol is a medicine that helps open your airways. It is used to make breathing easier for people with COPD.

Drug Pricing (NADAC)

Brand Price

$9.29/unit

Generic Price

$3.37/unit

Generic Savings

64%

Generic Available

Yes (9 manufacturers)

Pricing data from NADAC (CMS), effective December 25, 2024. Compare all drug costs →

What it does

Formoterol inhalation solution is used to treat chronic obstructive pulmonary disease (COPD).

Common side effects

Diarrhea, Nausea, Runny nose

Key warnings

If you have asthma, you should not take formoterol without also using an inhaled corticosteroid medicine.

How It Works

Formoterol is a long-acting beta-2 agonist (LABA). It works by relaxing the muscles around your airways. This allows more air to flow in and out of your lungs.

How to Take It

Use one 20 mcg vial twice a day, once in the morning and once in the evening. Use a nebulizer machine to breathe in the medicine. Do not use more than 40 mcg in one day. Always store the vial in its foil pouch until right before you use it.

Pregnancy & Breastfeeding

Tell your doctor if you are pregnant or plan to become pregnant. It is not known if formoterol will harm your unborn baby. Talk to your doctor about the risks and benefits of using formoterol during pregnancy. It is also not known if formoterol passes into breast milk.

Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and take your next dose at the regular time.

Storage

Store unopened vials in the refrigerator. Once dispensed, you can store it in the refrigerator or at room temperature for up to 3 months.

Side Effects (from patient reports)

Based on 5,565 FDA adverse event reports.

Difficulty breathing
1,076
Asthma
1,032
Cough
604
Wheezing
543
Pneumonia
416
Medicine not fully working
410
Blocked airways
404
Medicine not effective
376
Acid reflux
373
Headache
331

Serious Warnings

If you have asthma, you should not take formoterol without also using an inhaled corticosteroid medicine. Using formoterol alone for asthma can increase the risk of serious asthma problems, including death. Do not use formoterol to treat sudden breathing problems. Always have a rescue inhaler with you to treat sudden symptoms.

Known Drug Interactions

moderate aclidinium

May potentiate effect of formoterol fumarate on cardiovascular system. ( 7.6 ) 7.1 Adrenergic Drugs If additional adrenergic drugs are to be administered by any route, they should be used with caution because the sympathetic effects of formoterol, a component of DUAKLIR PRESSAIR, may be potentiated [see Warnings and Precautions (5.7) ] . 7.2 Xanthine Derivatives, Steroids Concomitant treatment with xanthine derivatives, or steroids may potentiate any hypokalemic effect of beta-adrenergic agonists such as formoterol, a component of DUAKLIR PRESSAIR.

Mechanism: These drugs can increase the effects on your heart and blood vessels. This might cause your heart to beat too fast or raise your blood pressure.

What to do: Use this combination with caution. Your doctor should check your heart health and blood pressure regularly while you are using these medicines.

May potentiate effect of formoterol on vascular system. 7.2 Monoamine Oxidase Inhibitors and Tricyclic Antidepressants SYMBICORT should be administered with caution to patients being treated with monoamine oxidase inhibitors or tricyclic antidepressants, or within 2 weeks of discontinuation of such agents, because the action of formoterol, a component of SYMBICORT, on the vascular system may be potentiated by these agents. 7.3 Beta-Adrenergic Receptor Blocking Agents Beta-blockers (including eye drops) may not only block the pulmonary effect of beta-agonists, such as formoterol, a component...

Mechanism: These medicines can work together to increase the effects of formoterol on your heart and blood vessels. This can lead to changes in your heart rate or blood pressure.

What to do: Use this combination with caution. Your doctor should monitor your heart health and blood pressure closely while you are taking these drugs.

May potentiate effect of formoterol fumarate on cardiovascular system. ( 7.6 ) 7.1 Adrenergic Drugs If additional adrenergic drugs are to be administered by any route, they should be used with caution because the sympathetic effects of formoterol, a component of BEVESPI AEROSPHERE, may be potentiated [see Warnings and Precautions (5.3) ] . 7.2 Xanthine Derivatives, Steroids, or Diuretics Concomitant treatment with xanthine derivatives, steroids, or diuretics may potentiate any hypokalemic effect of beta 2 adrenergic agonists such as formoterol, a component of BEVESPI AEROSPHERE.

Mechanism: Taking two drugs that work the same way can cause a stronger effect on your heart and nervous system. This happens because both drugs stimulate the same receptors in your body.

What to do: Use this combination with caution. Your doctor may need to monitor your heart rate and blood pressure more closely.

Common Questions

Can I use this medicine for a sudden asthma attack?
No, formoterol is not for treating sudden breathing problems. Use a rescue inhaler for quick relief.
How often should I use this medicine?
Use one vial twice a day, morning and evening.
What should I do if my breathing gets worse?
Contact your doctor right away if your breathing gets worse or if formoterol doesn't seem to be working as well.
Can I mix this medicine with other medicines in my nebulizer?
No, do not mix formoterol with other medicines in the nebulizer unless your doctor tells you to.
How should I store this medicine?
Store it in the refrigerator or at room temperature, protected from light and heat. Discard after 3 months if stored at room temperature.
What type of nebulizer should I use?
Use a standard jet nebulizer connected to an air compressor.
Is it okay if the solution is not clear?
The solution should be clear and colorless. If it's not, do not use it.
Can I take this medicine by mouth?
No, this medicine is only for inhalation using a nebulizer.
What if I accidentally use too much?
Seek medical attention immediately if you use too much formoterol.
Can I stop taking this medicine if I feel better?
Do not stop taking formoterol without talking to your doctor first.
What are the common side effects of formoterol?
The most commonly reported side effects of formoterol include Diarrhea, Nausea, Runny nose, Dry mouth, Vomiting. Based on 5,565 FDA adverse event reports. Always consult your healthcare provider about potential side effects.
Does formoterol interact with other medications?
Yes, formoterol has 3 known drug interactions. Notable interactions include aclidinium, budesonide/formoterol, glycopyrrolate/formoterol. Always inform your doctor about all medications you are taking.
What drug class is formoterol?
formoterol belongs to the Long-Acting Beta-2 Agonist (LABA) drug class. It requires a prescription (Rx). Formoterol inhalation solution is used to treat chronic obstructive pulmonary disease (COPD).
Is there a generic version of formoterol?
Yes, generic formoterol is available from 9 manufacturers. The generic costs $3.37 per unit compared to $9.29 for the brand version, saving approximately 64%. Pricing is based on NADAC (National Average Drug Acquisition Cost) data from CMS.
Is formoterol safe during pregnancy?
Tell your doctor if you are pregnant or plan to become pregnant. It is not known if formoterol will harm your unborn baby. Always consult your healthcare provider before using any medication during pregnancy or breastfeeding.

Related Medications in Long-Acting Beta-2 Agonist (LABA)

Other drugs grouped near formoterol — same-class peers and common alternatives.

Compare formoterol vs aclidinium side-by-side →

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Related Health & Safety Data

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What the FDA Data Shows for formoterol

The FDA label for formoterol (sold under brand names such as Foradil, Perforomist) classifies it as a prescription-only medication in the Long-Acting Beta-2 Agonist (LABA) class. Formoterol inhalation solution is used to treat chronic obstructive pulmonary disease (COPD). Official labeling lists 7 commonly reported side effects, including Diarrhea, Nausea, Runny nose.

Post-market surveillance from the FDA Adverse Event Reporting System (FAERS) captures real-world experience. For this drug, FAERS contains 5,565 voluntary reports. The database also lists 3 documented drug interactions derived from FDA labeling, with the top-flagged interaction rated moderate severity. NADAC pricing from CMS shows a generic unit cost of $3.37 versus $9.29 for the brand — a 64% generic savings.

Report counts do not establish causation — a FAERS entry documents a temporal association, not proof that the drug produced the outcome. Widely prescribed medications naturally accumulate more reports than niche therapies, so raw totals must be interpreted alongside total exposure. Shortage status, recall history, and patent information further shape supply and switching decisions. This page summarizes public FDA data for educational purposes only and is not a substitute for professional medical advice — always consult a licensed healthcare provider before starting, stopping, or changing any medication.

Data Sources

Drug labeling: FDA Drug Labels (SPL/DailyMed). Adverse events: FDA Adverse Event Reporting System (FAERS). Pricing: CMS National Average Drug Acquisition Cost (NADAC).

FAERS reports are voluntary and do not establish causation. Drug interactions are derived from FDA labeling and clinical references. Always consult a healthcare professional before making medication decisions.

Last updated: September 26, 2024

All federal data sources used on this page