Side effects across medicines
Medicines whose labels list anxiety
519 medicines have an FDA label that names anxiety in its boxed warning, warnings, adverse reactions, trial table, patient leaflet or Drug Facts “stop use” warning (of the labels PlainMeds reads: each medicine's quoted label and up to eight more, by route and wording). Among them, the most FAERS reports of anxiety name gabapentin (10,032), omeprazole (9,705) and clonazepam (8,893), through July 30, 2026. A label lists what its studies and reports found, and a report does not show that a medicine caused the event.
Check it at the source: the FDA FAERS public dashboard; FDA labels on DailyMed.
Which medicines' labels list anxiety?
Ordered by where the label names it, the boxed warning first, then by FAERS reports. The first 150 of the 519 are below; every other one is on its medicine record. A medicine whose own indications name it, because it treats it, is not counted.
| Medicine | Where a label names it | FAERS reports of anxiety |
|---|---|---|
| Clonazepam | precautions | 8,893 |
| Ciprofloxacin | warnings and precautions (intravenous label) | 4,180 |
| Metoclopramide | precautions (intramuscular/ | 4,098 |
| Levetiracetam | warnings and precautions (intravenous label) | 2,174 |
| Levofloxacin | warnings and precautions (intravenous label) | 1,426 |
| Moxifloxacin | warnings and precautions (intravenous label) | 816 |
| Elexacaftor and ivacaftor and tezacaftor | warnings and precautions | 614 |
| Ofloxacin | warnings (oral label) | 214 |
| Nortriptyline | precautions | 204 |
| Aspirin and caffeine and orphenadrine | precautions | none in the top 1,000 |
| Cycloserine | precautions | none in the top 1,000 |
| Isocarboxazid | precautions | none in the top 1,000 |
| Ivacaftor and tezacaftor | warnings and precautions | none in the top 1,000 |
| Mosunetuzumab | warnings and precautions (intravenous label) | none in the top 1,000 |
| Orphenadrine | precautions | none in the top 1,000 |
| Palovarotene | warnings and precautions | none in the top 1,000 |
| Phenobarbital | warnings and precautions (intravenous label) | none in the top 1,000 |
| Protriptyline | precautions | none in the top 1,000 |
| Viloxazine | warnings and precautions | none in the top 1,000 |
| Gabapentin | adverse reactions | 10,032 |
| Omeprazole | adverse reactions | 9,705 |
| Levothyroxine | adverse reactions | 8,889 |
| Oxycodone | adverse reactions | 8,029 |
| Quetiapine | adverse reactions | 7,884 |
| Pregabalin | adverse reactions | 7,486 |
| Varenicline | adverse reactions | 5,950 |
| Fluoxetine | adverse reactions | 5,768 |
| Bupropion | adverse reactions | 5,645 |
| Citalopram | adverse reactions | 5,542 |
| Zolpidem | adverse reactions | 5,523 |
| Metoprolol | adverse reactions | 5,273 |
| Aripiprazole | adverse reactions | 5,150 |
| Lamotrigine | adverse reactions | 4,459 |
| Amlodipine | adverse reactions | 4,452 |
| Acetaminophen and hydrocodone | adverse reactions | 4,203 |
| Celecoxib | adverse reactions | 4,012 |
| Fluticasone | adverse reactions (respiratory (inhalation) label) | 3,783 |
| Sodium oxybate | adverse reactions | 3,660 |
| Mirtazapine | adverse reactions | 3,579 |
| Morphine | adverse reactions | 3,475 |
| Hydromorphone | adverse reactions | 3,385 |
| Risperidone | adverse reactions | 3,233 |
| Diclofenac | adverse reactions (oral label) | 3,017 |
| Ondansetron | adverse reactions | 2,854 |
| Methylphenidate | adverse reactions | 2,795 |
| Natalizumab | adverse reactions | 2,791 |
| Topiramate | adverse reactions | 2,742 |
| Rituximab | adverse reactions | 2,678 |
| Tenofovir disoproxil | adverse reactions | 2,676 |
| Doxycycline | adverse reactions (intravenous label) | 2,581 |
| Fentanyl | adverse reactions (transdermal label) | 2,446 |
| Amoxicillin | adverse reactions | 2,353 |
| Azithromycin | adverse reactions | 2,242 |
| Estradiol | adverse reactions (transdermal label) | 2,204 |
| Baclofen | adverse reactions (intrathecal label) | 2,176 |
| Ramipril | adverse reactions | 2,148 |
| Digoxin | adverse reactions | 2,121 |
| Bisoprolol | adverse reactions | 2,062 |
| Omalizumab | adverse reactions | 2,044 |
| Teriparatide | adverse reactions | 2,028 |
| Sildenafil | adverse reactions | 2,008 |
| Cyclobenzaprine | adverse reactions | 1,990 |
| Hydroxychloroquine | adverse reactions | 1,943 |
| Isotretinoin | adverse reactions | 1,926 |
| Desvenlafaxine | adverse reactions | 1,818 |
| Lisdexamfetamine | adverse reactions | 1,802 |
| Buprenorphine | adverse reactions | 1,766 |
| Certolizumab | adverse reactions | 1,747 |
| Divalproex | adverse reactions | 1,715 |
| Cobicistat, elvitegravir, emtricitabine and tenofovir disoproxil | adverse reactions | 1,694 |
| Epinephrine | adverse reactions | 1,652 |
| Clonidine | adverse reactions | 1,632 |
| Temazepam | adverse reactions | 1,521 |
| Modafinil | adverse reactions | 1,501 |
| Estrogens conjugated | adverse reactions | 1,449 |
| Carbidopa and levodopa | adverse reactions | 1,418 |
| Buprenorphine and naloxone | adverse reactions | 1,361 |
| Ribavirin | adverse reactions | 1,331 |
| Peginterferon alfa 2a | adverse reactions | 1,287 |
| Tramadol | adverse reactions | 1,280 |
| Emtricitabine and rilpivirine and tenofovir disoproxil | adverse reactions | 1,263 |
| Rivaroxaban | adverse reactions | 1,259 |
| Letrozole | adverse reactions | 1,239 |
| Lurasidone | adverse reactions | 1,236 |
| Budesonide | adverse reactions | 1,221 |
| Armodafinil | adverse reactions | 1,178 |
| Naltrexone | adverse reactions | 1,098 |
| Acetaminophen and oxycodone | adverse reactions | 1,049 |
| Atomoxetine | adverse reactions | 1,042 |
| Botulinum toxin type a | adverse reactions (intradermal/ | 1,026 |
| Hydrocodone | adverse reactions | 973 |
| Raltegravir | adverse reactions | 966 |
| Glatiramer | adverse reactions | 965 |
| Anastrozole | adverse reactions | 958 |
| Testosterone | adverse reactions | 955 |
| Clarithromycin | adverse reactions | 939 |
| Cyclosporine | adverse reactions | 916 |
| Ethinyl estradiol and etonogestrel | adverse reactions | 878 |
| Niraparib | adverse reactions | 870 |
| Eszopiclone | adverse reactions | 865 |
| Amitriptyline | adverse reactions | 855 |
| Oxcarbazepine | adverse reactions | 811 |
| Medroxyprogesterone | adverse reactions (subcutaneous label) | 788 |
| Abacavir and dolutegravir and lamivudine | adverse reactions | 756 |
| Acetaminophen and codeine | adverse reactions | 723 |
| Leuprolide | adverse reactions | 721 |
| Lopinavir and ritonavir | adverse reactions | 713 |
| Nilotinib | adverse reactions | 710 |
| Valbenazine | adverse reactions | 678 |
| Calcium oxybate, magnesium oxybate, potassium oxybate and sodium oxybate | adverse reactions | 663 |
| Etonogestrel | adverse reactions | 656 |
| Bevacizumab | adverse reactions | 640 |
| Dexlansoprazole | adverse reactions | 635 |
| Isosorbide mononitrate | adverse reactions | 631 |
| Tacrolimus | adverse reactions | 630 |
| Felodipine | adverse reactions | 621 |
| Piroxicam | adverse reactions | 619 |
| Amoxicillin and clavulanate | adverse reactions | 615 |
| Brexpiprazole | adverse reactions | 612 |
| Nifedipine | adverse reactions | 609 |
| Mirabegron | adverse reactions | 593 |
| Paliperidone | adverse reactions | 590 |
| Ruxolitinib | adverse reactions (topical label) | 585 |
| Valproic acid | adverse reactions | 583 |
| Enzalutamide | adverse reactions | 578 |
| Lovastatin | adverse reactions | 561 |
| Fluticasone and umeclidinium and vilanterol | adverse reactions | 559 |
| Fulvestrant | adverse reactions | 541 |
| Propofol | adverse reactions | 527 |
| Trazodone | adverse reactions | 524 |
| Oseltamivir | adverse reactions | 486 |
| Zoledronic acid | adverse reactions | 482 |
| Abacavir | adverse reactions | 474 |
| Telmisartan | adverse reactions | 468 |
| Midazolam | adverse reactions | 465 |
| Aprepitant | adverse reactions | 449 |
| Amantadine | adverse reactions | 448 |
| Belimumab | adverse reactions | 437 |
| Exemestane | adverse reactions | 418 |
| Indomethacin | adverse reactions | 410 |
| Ropinirole | adverse reactions | 407 |
| Bupropion and naltrexone | adverse reactions | 405 |
| Zidovudine | adverse reactions | 397 |
| Rivastigmine | adverse reactions | 396 |
| Cariprazine | adverse reactions | 382 |
| Norepinephrine | adverse reactions | 370 |
| Cimetidine | adverse reactions | 358 |
| Human immunoglobulin g | adverse reactions | 357 |
| Alemtuzumab | adverse reactions | 340 |
| Solriamfetol | adverse reactions | 335 |
Source: FDA drug labels via openFDA, read October 8, 2026; FAERS via openFDA, reports through July 30, 2026
Which of them have the most anxiety reports in FAERS?
Counts follow how widely a medicine is used and watched, and they are not a measure of how risky it is.
Source: FDA Adverse Event Reporting System (FAERS) via openFDA, reports through July 30, 2026; MedDRA preferred term “Anxiety”
What next?
- Side effects across medicines
- every reaction on PlainMeds
- Report a side effect to the FDA
- MedWatch