Prescription medicine
Felodipine First approved as Plendil
Felodipine (Plendil) is a prescription medicine with an FDA approval on record since 1991. FDA's NDC Directory lists it from 14 generic labelers, and pharmacies paid $0.123 per felodipine ER 5 mg tablet in the October 7, 2026 NADAC survey.
- Generic listed
Check it at the source: the felodipine FDA label on DailyMed (effective August 11, 2026, Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.); the NDA 19834 record on Drugs@FDA; every felodipine label on DailyMed.
Highlights of the record
FDA label of August 11, 2026; NDC Directory, Drugs@FDA and Orange Book, October 8, 2026; NADAC October 7, 2026
Used for
From the label: indications and usageFelodipine extended-release tablets, USP are indicated for the treatment of hypertension, to lower blood pressure.
Forms and strengths
- 2.5 mg
- 5 mg
- 10 mg
Extended-release tablet; film-coated extended-release tablet; film-coated tablet.
On the market
- Earliest approval on file
- July 25, 1991 Plendil, Astrazeneca; Drugs@FDA’s file, where older or withdrawn approvals can be missing
- Generic approvals
- 13 first November 2, 2004; 9 with a marketed status in Drugs@FDA
- Labelers listed (NDC)
- 14 of which 14 under generic applications, 0 under brand applications, repackagers included
Supply and safety
- Pharmacy cost (NADAC)
- $0.123 per tablet Felodipine ER 5 mg tablet
- Shortage (FDA)
- No current entry
- Recalls by its makers (FDA)
- 3 since 2015 0 Class I among all firms' recalls; latest July 16, 2015; 1 more by firms not listed as its makers
- FAERS reports
- 11,323 through July 30, 2026
What is felodipine used for?
From the label: indications and usageFelodipine extended-release tablets, USP are indicated for the treatment of hypertension, to lower blood pressure. Lowering blood pressure lowers the risk of fatal and non-fatal cardiovascular events, primarily strokes and myocardial infarctions. These benefits have been seen in controlled trials of antihypertensive drugs from a wide variety of pharmacologic classes including felodipine. Control of high blood pressure should be part of comprehensive cardiovascular risk management, including, as appropriate, lipid control, diabetes management, antithrombotic therapy, smoking cessation, exercise, and limited sodium intake. […]
Conditions named in the indications of felodipine's FDA labels, with every medicine labeled for each:
From other felodipine labelsHigh blood pressure: INDICATIONS AND USAGE Felodipine extended-release tablets, USP are indicated for the treatment of hypertension, to lower blood pressure.
FDA pharmacologic class: Dihydropyridine Calcium Channel Blocker.
Source: FDA drug label (FELODIPINE), Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc., effective August 11, 2026 (SPL set 0bef7cf2-012b-4804-ac93-0a8b333035db), via openFDA; the full label on DailyMed
Is there a generic for felodipine (Plendil)?
The FDA approved the first generic felodipine on November 2, 2004. 13 generic applications are approved; 9 of them carry a current (not discontinued) marketing status in Drugs@FDA; that status is not evidence that the generic is on sale.
FDA's NDC Directory lists felodipine from 14 labelers under a generic (ANDA) application. A listing means the company has registered the product for sale; it does not show that every pharmacy stocks it.
- 1991 earliest approval on file
- 2004 first generic approved
- red ticks recalls
Source: Drugs@FDA, FDA NDC Directory and the Orange Book (openFDA bulk files, October 8, 2026)
What do pharmacies pay for felodipine (Plendil)?
In CMS's NADAC survey of October 7, 2026, pharmacies paid $0.123 per Felodipine ER 5 mg tablet, down 27% from $0.168 on October 8, 2025. The chart's scale runs from the lowest to the highest price shown, not from zero. NADAC is what retail pharmacies paid their wholesalers, per unit, in CMS's monthly survey; what a patient pays depends on insurance and the pharmacy.
- Felodipine ER 5 mg tablet (generic)
| Strength and form | Brand or generic | Pharmacy cost | 30 tablets, or one pen or vial | 12-month change |
|---|---|---|---|---|
| Felodipine ER 10 mg tablet | Generic | $0.135 per tablet | $4.06 | -10% |
| Felodipine ER 2.5 mg tablet | Generic | $0.127 per tablet | $3.81 | -24% |
| Felodipine ER 5 mg tablet | Generic | $0.123 per tablet | $3.68 | -27% |
Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price
Has felodipine been recalled?
The FDA's Enforcement Report lists 4 recalls naming felodipine since 2015: 0 Class I (the most serious), 0 Class II, 4 Class III; 0 still ongoing. 1 of them is by a firm that FDA's NDC Directory does not list as a maker of felodipine and that holds no application for it in Drugs@FDA, such as compounding pharmacies or bulk-ingredient suppliers; the recall notice names the product recalled. A recall names products and lots, not every product of the medicine.
| Started | Class | Company | Reason |
|---|---|---|---|
| October 23, 2020 | Class III | Heritage Pharmaceuticals Inc not a listed maker | Failed impurities/ degradation specifications: Out of specification impurity results were observed during routine testing of stability samples for the impurity … |
| July 16, 2015 | Class III | Mutual Pharmaceutical Company, Inc. | Chemical Contamination; benzophenone leached from the product label varnish |
Source: FDA Enforcement Report (drug recalls) via openFDA, through October 8, 2026
What does the felodipine label say about other medicines?
The felodipine label names no other medicine on this site. The labels of 25 other medicines name felodipine. The sentences are the labels' own; a label lists what its studies and reports found, not every interaction.
Other labels that name felodipine
Source: FDA drug label (FELODIPINE), Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc., effective August 11, 2026 (SPL set 0bef7cf2-012b-4804-ac93-0a8b333035db), via openFDA; the full label on DailyMed
What do FAERS reports show for felodipine?
The FDA Adverse Event Reporting System holds 11,323 reports that list felodipine among the medicines taken, through July 30, 2026, each a report of something that happened, not proof the medicine caused it; 846 are coded as a death and 5,004 as a hospital stay. Counts follow how widely a medicine is used and watched, and they are not a measure of how risky it is.
Reports received each year
The most reported reactions
Source: FDA Adverse Event Reporting System (FAERS) via openFDA, reports through July 30, 2026
What else is labeled for the same conditions as felodipine?
72 other medicines are given the same way (oral) and in the same FDA class as felodipine or labeled mainly for the same use (high blood pressure), the same class first. High blood pressure lists all 88 medicines labeled for it, by any route. The first 8 are below. They are listed as records, not as substitutes: whether one can replace another is a prescriber's decision.
| Medicine | Shared indication | Generic labelers (oral) | Pharmacy cost | Shortage |
|---|---|---|---|---|
| Amlodipine | High blood pressure | 42 labelers | $0.0102 per tablet 5 mg tablet | No current entry |
| Nifedipine | High blood pressure | 32 labelers | $0.130 per tablet 30 mg tablet | No current entry |
| Amlodipine and benazepril | High blood pressure | 16 labelers | $0.114 per unit 10-20 mg | No current entry |
| Amlodipine and atorvastatin | High blood pressure | 6 labelers | $1.34 per unit 10-40 mg | No current entry |
| Amlodipine and olmesartan | High blood pressure | 14 labelers | $0.248 per unit 10-20 mg | No current entry |
| Amlodipine and hydrochlorothiazide and olmesartan | High blood pressure | 8 labelers | $0.776 per unit 20-5-12.5 | No current entry |
| Amlodipine and valsartan | High blood pressure | 9 labelers | $0.330 per unit 10-160 mg | No current entry |
| Amlodipine and hydrochlorothiazide and valsartan | High blood pressure | 5 labelers | $6.09 per tablet 10-160-25 mg tablet | No current entry |
Every medicine labeled for the same conditions as felodipine
Source: FDA drug labels (indications), NDC Directory, NADAC of October 7, 2026, FDA shortages (October 8, 2026)
How does felodipine compare with medicines for the same use?
5 side-by-side pages set felodipine beside a medicine whose label shares a use: approvals, generics, pharmacy cost, warnings and supply.
What next?
- Alternatives to felodipine
- 72 medicines for the same use
- Other calcium channel blockers
- the pharmacologic class, with prices and generics
- Felodipine side effects
- the label's list beside FAERS reports
- Check an interaction
- what two or more labels say about each other