Side effects across medicines
Medicines whose labels list shortness of breath
940 medicines have an FDA label that names shortness of breath (dyspnea) in its boxed warning, warnings, adverse reactions, trial table, patient leaflet or Drug Facts “stop use” warning (of the labels PlainMeds reads: each medicine's quoted label and up to eight more, by route and wording). Among them, the most FAERS reports of shortness of breath name tiotropium (22,576), treprostinil (21,363) and omeprazole (20,988), through July 30, 2026. A label lists what its studies and reports found, and a report does not show that a medicine caused the event.
Check it at the source: the FDA FAERS public dashboard; FDA labels on DailyMed.
Which medicines' labels list shortness of breath?
Ordered by where the label names it, the boxed warning first, then by FAERS reports. The first 152 of the 940 are below; every other one is on its medicine record. A medicine whose own indications name it, because it treats it, is not counted.
| Medicine | Where a label names it | FAERS reports of shortness of breath |
|---|---|---|
| Diclofenac | precautions (oral label) | 7,705 |
| Paclitaxel | precautions | 5,112 |
| Sulfamethoxazole and trimethoprim | precautions | 4,479 |
| Levofloxacin | warnings and precautions (ophthalmic label) | 3,047 |
| Moxifloxacin | warnings and precautions (ophthalmic label) | 2,203 |
| Amikacin | warnings and precautions (respiratory (inhalation) label) | 1,626 |
| Aprepitant | warnings and precautions (intravenous label) | 1,583 |
| Insulin human | warnings and precautions (subcutaneous label) | 1,279 |
| Progesterone | warnings (intramuscular label) | 683 |
| Eszopiclone | warnings and precautions (oropharyngeal label) | 666 |
| Testosterone | warnings and precautions (subcutaneous label) | 623 |
| Vincristine | precautions | 510 |
| Rifampin | precautions | 414 |
| Amantadine | precautions | 378 |
| Interferon beta 1b | warnings and precautions | 374 |
| Tranexamic acid | warnings and precautions (oral label) | 287 |
| Methimazole | precautions | 277 |
| Alpha-tocopherol, ascorbic acid and 11 other ingredients | warnings and precautions | none in the top 1,000 |
| Alpha-tocopherol, ascorbic acid and 11 other ingredients | warnings and precautions | none in the top 1,000 |
| Axatilimab | warnings and precautions | none in the top 1,000 |
| Benzocaine | warnings (dental/ | none in the top 1,000 |
| Busulfan | warnings (oral label) | none in the top 1,000 |
| Cabotegravir and rilpivirine | warnings and precautions | none in the top 1,000 |
| Cromolyn | warnings (nasal label) | none in the top 1,000 |
| Dantrolene | warnings and precautions (intravenous label) | none in the top 1,000 |
| Daratumumab | warnings and precautions | none in the top 1,000 |
| Dicloxacillin | precautions | none in the top 1,000 |
| Diflunisal | precautions | none in the top 1,000 |
| Doxapram | precautions | none in the top 1,000 |
| Doxercalciferol | warnings and precautions (oral label) | none in the top 1,000 |
| Etodolac | precautions | none in the top 1,000 |
| Hyaluronidase and pertuzumab and trastuzumab | warnings and precautions | none in the top 1,000 |
| Hyaluronidase and trastuzumab | warnings and precautions | none in the top 1,000 |
| Hydrocodone and ibuprofen | precautions | none in the top 1,000 |
| Isatuximab | warnings and precautions (subcutaneous label) | none in the top 1,000 |
| Ivermectin | precautions (oral label) | none in the top 1,000 |
| Ketorolac | precautions | none in the top 1,000 |
| Meclofenamate | precautions | none in the top 1,000 |
| Menotropins | warnings and precautions | none in the top 1,000 |
| Mitomycin | precautions | none in the top 1,000 |
| Multiple vitamins | warnings and precautions | none in the top 1,000 |
| Nabumetone | precautions | none in the top 1,000 |
| Nilutamide | precautions | none in the top 1,000 |
| Obiltoxaximab | warnings and precautions | none in the top 1,000 |
| Ofloxacin | warnings (oral label) | none in the top 1,000 |
| Propylthiouracil | precautions | none in the top 1,000 |
| Sulfur hexafluoride | warnings and precautions | none in the top 1,000 |
| Sulindac | precautions | none in the top 1,000 |
| Temsirolimus | warnings and precautions (intravenous label) | none in the top 1,000 |
| Teprotumumab | warnings and precautions | none in the top 1,000 |
| Tolmetin | precautions | none in the top 1,000 |
| Trastuzumab-strf | warnings and precautions | none in the top 1,000 |
| Ubrogepant | warnings and precautions | none in the top 1,000 |
| Vinblastine | precautions | none in the top 1,000 |
| Treprostinil | adverse reactions | 21,363 |
| Levothyroxine | adverse reactions | 16,134 |
| Adalimumab | adverse reactions | 15,817 |
| Metoprolol | adverse reactions | 15,641 |
| Amlodipine | adverse reactions | 13,612 |
| Sildenafil | adverse reactions | 13,324 |
| Simvastatin | adverse reactions | 12,640 |
| Tadalafil | adverse reactions | 11,993 |
| Infliximab | adverse reactions | 10,617 |
| Mepolizumab | adverse reactions | 10,576 |
| Pregabalin | adverse reactions | 10,458 |
| Omalizumab | adverse reactions | 10,335 |
| Rituximab | adverse reactions | 10,326 |
| Fluticasone and salmeterol | adverse reactions | 9,965 |
| Bisoprolol | adverse reactions | 9,172 |
| Losartan | adverse reactions | 8,854 |
| Fluticasone | adverse reactions (respiratory (inhalation) label) | 8,659 |
| Carvedilol | adverse reactions | 8,390 |
| Ramipril | adverse reactions | 8,357 |
| Potassium chloride | adverse reactions (intravenous label) | 8,130 |
| Oxycodone | adverse reactions | 8,077 |
| Lenalidomide | adverse reactions | 7,673 |
| Leflunomide | adverse reactions | 7,136 |
| Clonazepam | adverse reactions | 7,069 |
| Tocilizumab | adverse reactions | 7,001 |
| Tofacitinib | adverse reactions | 6,544 |
| Celecoxib | adverse reactions | 6,373 |
| Atenolol | adverse reactions | 6,354 |
| Abatacept | adverse reactions | 6,070 |
| Ipratropium | adverse reactions (respiratory (inhalation) label) | 6,049 |
| Ondansetron | adverse reactions | 5,970 |
| Quetiapine | adverse reactions | 5,530 |
| Citalopram | adverse reactions | 5,421 |
| Zolpidem | adverse reactions | 5,257 |
| Certolizumab | adverse reactions | 5,243 |
| Ciprofloxacin | adverse reactions | 4,734 |
| Venlafaxine | adverse reactions | 4,579 |
| Diazepam | adverse reactions (intramuscular/ | 4,411 |
| Mycophenolate mofetil | adverse reactions | 4,232 |
| Ticagrelor | adverse reactions | 4,009 |
| Denosumab | adverse reactions | 3,752 |
| Mirtazapine | adverse reactions | 3,536 |
| Bevacizumab | adverse reactions (intravascular label) | 3,406 |
| Ribavirin | adverse reactions | 3,336 |
| Diltiazem | adverse reactions | 3,296 |
| Palbociclib | adverse reactions | 3,293 |
| Metoclopramide | adverse reactions (intramuscular/ | 3,261 |
| Insulin lispro | adverse reactions | 3,156 |
| Oxaliplatin | adverse reactions | 3,084 |
| Ustekinumab | adverse reactions | 3,073 |
| Peginterferon alfa 2a | adverse reactions | 3,051 |
| Fentanyl | adverse reactions (transdermal label) | 3,026 |
| Topiramate | adverse reactions | 2,990 |
| Lamotrigine | adverse reactions | 2,979 |
| Letrozole | adverse reactions | 2,935 |
| Glatiramer | adverse reactions | 2,907 |
| Pomalidomide | adverse reactions | 2,846 |
| Trastuzumab | adverse reactions | 2,830 |
| Epoprostenol | adverse reactions | 2,777 |
| Baclofen | adverse reactions | 2,705 |
| Enalapril | adverse reactions | 2,701 |
| Adalimumab-aaty | adverse reactions | 2,685 |
| Nivolumab | adverse reactions | 2,683 |
| Propranolol | adverse reactions (intravenous label) | 2,673 |
| Capecitabine | adverse reactions | 2,671 |
| Adalimumab-fkjp | adverse reactions | 2,668 |
| Hydromorphone | adverse reactions | 2,655 |
| Cyclosporine | adverse reactions | 2,639 |
| Everolimus | adverse reactions | 2,597 |
| Teriparatide | adverse reactions | 2,588 |
| Tacrolimus | adverse reactions | 2,519 |
| Tramadol | adverse reactions | 2,454 |
| Enoxaparin | adverse reactions | 2,428 |
| Docetaxel | adverse reactions | 2,377 |
| Clonidine | adverse reactions (epidural label) | 2,354 |
| Epinephrine and lidocaine | adverse reactions (submucosal label) | 2,353 |
| Pembrolizumab | adverse reactions | 2,351 |
| Olanzapine | adverse reactions | 2,342 |
| Fingolimod | adverse reactions | 2,236 |
| Cyclobenzaprine | adverse reactions | 2,224 |
| Nifedipine | adverse reactions | 2,178 |
| Finasteride | adverse reactions | 2,171 |
| Valacyclovir | adverse reactions | 2,128 |
| Bortezomib | adverse reactions | 2,095 |
| Varenicline | adverse reactions | 2,084 |
| Natalizumab | adverse reactions | 2,058 |
| Risperidone | adverse reactions | 2,002 |
| Ruxolitinib | adverse reactions | 1,987 |
| Doxazosin | adverse reactions | 1,985 |
| Vancomycin | adverse reactions | 1,864 |
| Mesalamine | adverse reactions | 1,795 |
| Temazepam | adverse reactions | 1,780 |
| Buprenorphine | adverse reactions (transdermal label) | 1,767 |
| Formoterol and mometasone | adverse reactions | 1,726 |
| Nebivolol | adverse reactions | 1,724 |
| Ibrutinib | adverse reactions | 1,673 |
| Tiotropium | patient leaflet | 22,576 |
| Omeprazole | patient leaflet | 20,988 |
Source: FDA drug labels via openFDA, read October 8, 2026; FAERS via openFDA, reports through July 30, 2026
Which of them have the most shortness of breath reports in FAERS?
Counts follow how widely a medicine is used and watched, and they are not a measure of how risky it is.
Source: FDA Adverse Event Reporting System (FAERS) via openFDA, reports through July 30, 2026; MedDRA preferred term “Dyspnoea”
What next?
- Side effects across medicines
- every reaction on PlainMeds
- Report a side effect to the FDA
- MedWatch