Side effects across medicines
Medicines whose labels list flushing
418 medicines have an FDA label that names flushing in its boxed warning, warnings, adverse reactions, trial table, patient leaflet or Drug Facts “stop use” warning (of the labels PlainMeds reads: each medicine's quoted label and up to eight more, by route and wording). Among them, the most FAERS reports of flushing name dimethyl fumarate (17,099), treprostinil (3,846) and lisinopril (3,785), through July 30, 2026. A label lists what its studies and reports found, and a report does not show that a medicine caused the event.
Check it at the source: the FDA FAERS public dashboard; FDA labels on DailyMed.
Which medicines' labels list flushing?
Ordered by where the label names it, the boxed warning first, then by FAERS reports. The first 150 of the 418 are below; every other one is on its medicine record. A medicine whose own indications name it, because it treats it, is not counted.
| Medicine | Where a label names it | FAERS reports of flushing |
|---|---|---|
| Furosemide | precautions | 2,528 |
| Paclitaxel | precautions | 1,630 |
| Enalapril | precautions | 335 |
| Metronidazole | precautions | 312 |
| Brimonidine | warnings and precautions (topical label) | 306 |
| Aprepitant | warnings and precautions (intravenous label) | 284 |
| Hydrochlorothiazide and lisinopril | precautions | 191 |
| Obinutuzumab | warnings and precautions | 134 |
| Quinapril | precautions | 109 |
| Atropine and diphenoxylate | precautions | 101 |
| Magnesium sulfate | precautions (intramuscular/ | 97 |
| Ketoconazole | precautions (oral label) | 66 |
| Captopril | precautions | 62 |
| Clobetasol | precautions | 55 |
| Tranexamic acid | warnings and precautions (oral label) | 41 |
| Cabotegravir and rilpivirine | warnings and precautions | 40 |
| Fosinopril | precautions | 38 |
| Temsirolimus | warnings and precautions (intravenous label) | 37 |
| Arginine | precautions | none in the top 1,000 |
| Axatilimab | warnings and precautions | none in the top 1,000 |
| Benazepril and hydrochlorothiazide | precautions | none in the top 1,000 |
| Bivalirudin | warnings and precautions (intracavernous label) | none in the top 1,000 |
| Captopril and hydrochlorothiazide | precautions | none in the top 1,000 |
| Cefotetan | precautions | none in the top 1,000 |
| Enalapril and hydrochlorothiazide | precautions | none in the top 1,000 |
| Enalaprilat | precautions | none in the top 1,000 |
| Fosinopril and hydrochlorothiazide | precautions | none in the top 1,000 |
| Hydrochlorothiazide and quinapril | precautions | none in the top 1,000 |
| Mesna | warnings and precautions (oral label) | none in the top 1,000 |
| Moexipril | precautions | none in the top 1,000 |
| Pralidoxime | precautions | none in the top 1,000 |
| Trandolapril and verapamil | precautions | none in the top 1,000 |
| Dimethyl fumarate | adverse reactions | 17,099 |
| Treprostinil | adverse reactions (oral label) | 3,846 |
| Lisinopril | adverse reactions | 3,785 |
| Levothyroxine | adverse reactions | 3,435 |
| Simvastatin | adverse reactions | 3,010 |
| Tadalafil | adverse reactions | 2,834 |
| Sildenafil | adverse reactions | 2,785 |
| Ambrisentan | adverse reactions | 2,685 |
| Infliximab | adverse reactions | 2,529 |
| Amlodipine | adverse reactions | 1,641 |
| Diroximel fumarate | adverse reactions | 1,611 |
| Macitentan | adverse reactions | 1,599 |
| Albuterol | adverse reactions (oral label) | 1,490 |
| Methylprednisolone | adverse reactions | 1,205 |
| Epoprostenol | adverse reactions | 1,169 |
| Escitalopram | adverse reactions | 1,166 |
| Selexipag | adverse reactions | 1,147 |
| Ondansetron | adverse reactions | 1,096 |
| Clonazepam | adverse reactions | 1,082 |
| Natalizumab | adverse reactions | 1,055 |
| Citalopram | adverse reactions | 1,017 |
| Zolpidem | adverse reactions | 970 |
| Rituximab | adverse reactions | 946 |
| Bupropion | adverse reactions | 864 |
| Oxaliplatin | adverse reactions | 774 |
| Topiramate | adverse reactions | 628 |
| Bosentan | adverse reactions | 604 |
| Lamotrigine | adverse reactions | 508 |
| Ascorbic acid | adverse reactions | 481 |
| Alemtuzumab | adverse reactions | 453 |
| Perflutren | adverse reactions | 414 |
| Ezetimibe and simvastatin | adverse reactions | 407 |
| Bisoprolol | adverse reactions | 383 |
| Metoclopramide | adverse reactions (intramuscular/ | 381 |
| Duloxetine | adverse reactions | 376 |
| Lovastatin | adverse reactions | 368 |
| Sumatriptan | adverse reactions (subcutaneous label) | 362 |
| Monomethyl fumarate | adverse reactions | 348 |
| Ciprofloxacin | adverse reactions | 339 |
| Nitroglycerin | adverse reactions | 314 |
| Cetuximab | adverse reactions | 304 |
| Niacin | adverse reactions | 297 |
| Vancomycin | adverse reactions (oral label) | 284 |
| Etoposide | adverse reactions | 283 |
| Nifedipine | adverse reactions | 272 |
| Budesonide | adverse reactions (oral label) | 261 |
| Capecitabine | adverse reactions | 249 |
| Diltiazem | adverse reactions (intravenous label) | 245 |
| Ustekinumab | adverse reactions | 244 |
| Morphine | adverse reactions | 243 |
| Flutemetamol f 18 | adverse reactions | 242 |
| Cyclosporine | adverse reactions | 234 |
| Abatacept | adverse reactions | 231 |
| Cyclophosphamide | adverse reactions | 215 |
| Oxybutynin | adverse reactions | 210 |
| Pegfilgrastim | adverse reactions | 204 |
| Hydromorphone | adverse reactions | 190 |
| Methocarbamol | adverse reactions | 183 |
| Benazepril | adverse reactions | 175 |
| Ferric carboxymaltose | adverse reactions | 173 |
| Propofol | adverse reactions | 163 |
| Risperidone | adverse reactions | 156 |
| Oxcarbazepine | adverse reactions | 153 |
| Ferric derisomaltose | adverse reactions | 149 |
| Human immunoglobulin g | adverse reactions | 149 |
| Letrozole | adverse reactions | 147 |
| Iohexol | adverse reactions | 137 |
| Carbidopa and levodopa | adverse reactions | 133 |
| Iopromide | adverse reactions | 132 |
| Granisetron | adverse reactions (subcutaneous label) | 129 |
| Buspirone | adverse reactions | 123 |
| Rizatriptan | adverse reactions | 116 |
| Ceftriaxone | adverse reactions | 111 |
| Eptinezumab | adverse reactions | 111 |
| Iron dextran | adverse reactions | 110 |
| Atomoxetine | adverse reactions | 107 |
| Milnacipran | adverse reactions | 104 |
| Mepolizumab | adverse reactions | 102 |
| Hydrochlorothiazide and irbesartan | adverse reactions | 97 |
| Ropinirole | adverse reactions | 95 |
| Amlodipine and olmesartan | adverse reactions | 93 |
| Indapamide | adverse reactions | 92 |
| Buprenorphine | adverse reactions (intramuscular/ | 90 |
| Iodixanol | adverse reactions | 89 |
| Liothyronine | adverse reactions | 86 |
| Methadone | adverse reactions | 84 |
| Telmisartan | adverse reactions | 79 |
| Felodipine | adverse reactions | 78 |
| Acetylcysteine | adverse reactions | 74 |
| Desmopressin | adverse reactions | 74 |
| Isosorbide mononitrate | adverse reactions | 74 |
| Sorafenib | adverse reactions | 74 |
| Bremelanotide | adverse reactions | 72 |
| Ioversol | adverse reactions | 71 |
| Cromolyn | adverse reactions (oral label) | 70 |
| Piperacillin and tazobactam | adverse reactions | 68 |
| Vortioxetine | adverse reactions | 68 |
| Regadenoson | adverse reactions | 67 |
| Amlodipine and atorvastatin | adverse reactions | 65 |
| Doxepin | adverse reactions | 64 |
| Panitumumab | adverse reactions | 64 |
| Irinotecan | adverse reactions | 62 |
| Indomethacin | adverse reactions | 60 |
| Isotretinoin | adverse reactions | 59 |
| Lutetium oxodotreotide lu 177 | adverse reactions | 58 |
| Phytonadione | adverse reactions | 55 |
| Sodium ferric gluconate complex | adverse reactions | 55 |
| Acetaminophen and oxycodone | adverse reactions | 54 |
| Amiodarone | adverse reactions | 52 |
| Eletriptan | adverse reactions | 51 |
| Labetalol | adverse reactions (intravenous label) | 51 |
| Midodrine | adverse reactions | 50 |
| Carfilzomib | adverse reactions | 47 |
| Flecainide | adverse reactions | 47 |
| Tramadol | adverse reactions | 47 |
| Etodolac | adverse reactions | 45 |
| Nortriptyline | adverse reactions | 45 |
| Nilotinib | adverse reactions | 44 |
Source: FDA drug labels via openFDA, read October 8, 2026; FAERS via openFDA, reports through July 30, 2026
Which of them have the most flushing reports in FAERS?
Counts follow how widely a medicine is used and watched, and they are not a measure of how risky it is.
Source: FDA Adverse Event Reporting System (FAERS) via openFDA, reports through July 30, 2026; MedDRA preferred term “Flushing”
What next?
- Side effects across medicines
- every reaction on PlainMeds
- Report a side effect to the FDA
- MedWatch