Side effects across medicines
Medicines whose labels list excessive sweating
147 medicines have an FDA label that names excessive sweating (hyperhidrosis) in its boxed warning, warnings, adverse reactions, trial table, patient leaflet or Drug Facts “stop use” warning (of the labels PlainMeds reads: each medicine's quoted label and up to eight more, by route and wording). Among them, the most FAERS reports of excessive sweating name omeprazole (4,623), levothyroxine (4,062) and quetiapine (2,714), through July 30, 2026. A label lists what its studies and reports found, and a report does not show that a medicine caused the event.
Check it at the source: the FDA FAERS public dashboard; FDA labels on DailyMed.
Which medicines' labels list excessive sweating?
Ordered by where the label names it, the boxed warning first, then by FAERS reports. A medicine whose own indications name it, because it treats it, is not counted.
| Medicine | Where a label names it | FAERS reports of excessive sweating |
|---|---|---|
| Mecamylamine | precautions | none in the top 1,000 |
| Omeprazole | adverse reactions | 4,623 |
| Levothyroxine | adverse reactions | 4,062 |
| Esomeprazole | adverse reactions (intravenous label) | 2,589 |
| Oxycodone | adverse reactions | 2,020 |
| Sertraline | adverse reactions | 1,786 |
| Duloxetine | adverse reactions | 1,778 |
| Hydromorphone | adverse reactions | 1,387 |
| Fentanyl | adverse reactions (transdermal label) | 1,351 |
| Buprenorphine | adverse reactions (transdermal label) | 1,256 |
| Interferon beta 1a | adverse reactions | 1,153 |
| Exenatide | adverse reactions | 1,108 |
| Temazepam | adverse reactions | 1,094 |
| Sodium oxybate | adverse reactions | 1,037 |
| Relugolix | adverse reactions | 764 |
| Desvenlafaxine | adverse reactions | 762 |
| Methylphenidate | adverse reactions | 751 |
| Varenicline | adverse reactions | 700 |
| Moxifloxacin | adverse reactions | 651 |
| Octreotide | adverse reactions (oral label) | 611 |
| Glatiramer | adverse reactions | 593 |
| Atomoxetine | adverse reactions | 478 |
| Lisdexamfetamine | adverse reactions | 478 |
| Metronidazole | adverse reactions (intravenous label) | 459 |
| Almotriptan | adverse reactions | 448 |
| Clarithromycin | adverse reactions | 411 |
| Cyclophosphamide | adverse reactions | 387 |
| Vortioxetine | adverse reactions | 305 |
| Milnacipran | adverse reactions | 286 |
| Pomalidomide | adverse reactions | 286 |
| Calcium oxybate, magnesium oxybate, potassium oxybate and sodium oxybate | adverse reactions | 266 |
| Iron sucrose | adverse reactions | 261 |
| Tapentadol | adverse reactions | 234 |
| Bupropion and naltrexone | adverse reactions | 219 |
| Hydrocodone | adverse reactions | 200 |
| Medroxyprogesterone | adverse reactions (intramuscular label) | 196 |
| Nilotinib | adverse reactions | 192 |
| Naloxegol | adverse reactions | 185 |
| Aprepitant | adverse reactions | 169 |
| Iopromide | adverse reactions | 169 |
| Bupivacaine | adverse reactions | 154 |
| Liothyronine | adverse reactions | 153 |
| Vilazodone | adverse reactions | 148 |
| Acetaminophen and butalbital and caffeine | adverse reactions | 146 |
| Brexpiprazole | adverse reactions | 138 |
| Iohexol | adverse reactions | 134 |
| Lubiprostone | adverse reactions | 129 |
| Lacosamide | adverse reactions | 119 |
| Gadobutrol | adverse reactions | 110 |
| Ospemifene | adverse reactions | 107 |
| Gadobenate | adverse reactions | 105 |
| Cariprazine | adverse reactions | 103 |
| Bupropion and dextromethorphan | adverse reactions | 99 |
| Solriamfetol | adverse reactions | 95 |
| Gadoterate | adverse reactions | 85 |
| Ranolazine | adverse reactions | 84 |
| Levomilnacipran | adverse reactions | 83 |
| Degarelix | adverse reactions | 82 |
| Dextroamphetamine | adverse reactions (transdermal label) | 75 |
| Agalsidase beta | adverse reactions | 74 |
| Carfilzomib | adverse reactions | 69 |
| Tetrabenazine | adverse reactions | 69 |
| Dexmethylphenidate | adverse reactions | 65 |
| Fosinopril | adverse reactions | 63 |
| Ioversol | adverse reactions | 61 |
| Febuxostat | adverse reactions | 54 |
| Acetaminophen and butalbital | adverse reactions | none in the top 1,000 |
| Acetaminophen and ibuprofen | adverse reactions (intravenous label) | none in the top 1,000 |
| Acetaminophen, butalbital, caffeine and codeine | adverse reactions | none in the top 1,000 |
| Alglucosidase alfa | adverse reactions | none in the top 1,000 |
| Amlodipine and benazepril | adverse reactions | none in the top 1,000 |
| Amoxicillin and clarithromycin and lansoprazole | adverse reactions | none in the top 1,000 |
| Amoxicillin and omeprazole and rifabutin | adverse reactions | none in the top 1,000 |
| Aripiprazole lauroxil | adverse reactions | none in the top 1,000 |
| Aspirin, butalbital, caffeine and codeine | adverse reactions | none in the top 1,000 |
| Avalglucosidase alfa | adverse reactions | none in the top 1,000 |
| Belatacept | adverse reactions | none in the top 1,000 |
| Bendamustine | adverse reactions | none in the top 1,000 |
| Bupivacaine and epinephrine | adverse reactions | none in the top 1,000 |
| Bupivacaine and meloxicam | adverse reactions | none in the top 1,000 |
| Carglumic acid | adverse reactions | none in the top 1,000 |
| Cevimeline | adverse reactions | none in the top 1,000 |
| Chloroprocaine | adverse reactions | none in the top 1,000 |
| Chlorpheniramine and codeine | adverse reactions | none in the top 1,000 |
| Chlorpheniramine and hydrocodone | adverse reactions | none in the top 1,000 |
| Cilastatin and imipenem | adverse reactions | none in the top 1,000 |
| Cipaglucosidase alfa | adverse reactions | none in the top 1,000 |
| Cladribine | adverse reactions (intravenous label) | none in the top 1,000 |
| Codeine and phenylephrine and promethazine | adverse reactions | none in the top 1,000 |
| Codeine and promethazine | adverse reactions | none in the top 1,000 |
| Dasatinib | adverse reactions | none in the top 1,000 |
| Deferiprone | adverse reactions | none in the top 1,000 |
| Dexmedetomidine | adverse reactions | none in the top 1,000 |
| Dexmethylphenidate and serdexmethylphenidate | adverse reactions | none in the top 1,000 |
| Doxylamine and pyridoxine | adverse reactions | none in the top 1,000 |
| Emapalumab | adverse reactions | none in the top 1,000 |
| Eravacycline | adverse reactions | none in the top 1,000 |
| Esketamine | adverse reactions | none in the top 1,000 |
| Esmolol | adverse reactions | none in the top 1,000 |
| Estradiol and norethindrone and relugolix | adverse reactions | none in the top 1,000 |
| Ethinyl estradiol and norgestimate | adverse reactions | none in the top 1,000 |
| Etravirine | adverse reactions | none in the top 1,000 |
| Fexinidazole | adverse reactions | none in the top 1,000 |
| Fish oil, medium-chain triglycerides, olive oil and soybean oil | adverse reactions | none in the top 1,000 |
| Gadoteridol | adverse reactions | none in the top 1,000 |
| Gadoxetate | adverse reactions | none in the top 1,000 |
| Ganciclovir | adverse reactions | none in the top 1,000 |
| Gepirone | adverse reactions | none in the top 1,000 |
| Gepotidacin | adverse reactions | none in the top 1,000 |
| Homatropine methylbromide and hydrocodone | adverse reactions | none in the top 1,000 |
| Hydralazine and isosorbide dinitrate | adverse reactions | none in the top 1,000 |
| Ifosfamide | adverse reactions | none in the top 1,000 |
| Inotuzumab ozogamicin | adverse reactions | none in the top 1,000 |
| Iopamidol | adverse reactions | none in the top 1,000 |
| Isradipine | adverse reactions | none in the top 1,000 |
| Itraconazole | adverse reactions | none in the top 1,000 |
| Laronidase | adverse reactions | none in the top 1,000 |
| Macimorelin | adverse reactions | none in the top 1,000 |
| Mepivacaine | adverse reactions (infiltration label) | none in the top 1,000 |
| Mesna | adverse reactions | none in the top 1,000 |
| Methylnaltrexone | adverse reactions | none in the top 1,000 |
| Midostaurin | adverse reactions | none in the top 1,000 |
| Naldemedine | adverse reactions | none in the top 1,000 |
| Nalmefene | adverse reactions (nasal label) | none in the top 1,000 |
| Naxitamab | adverse reactions | none in the top 1,000 |
| Oliceridine | adverse reactions | none in the top 1,000 |
| Omadacycline | adverse reactions | none in the top 1,000 |
| Pindolol | adverse reactions | none in the top 1,000 |
| Plerixafor | adverse reactions | none in the top 1,000 |
| Rifapentine | adverse reactions | none in the top 1,000 |
| Ropeginterferon alfa 2b | adverse reactions | none in the top 1,000 |
| Ropivacaine | adverse reactions | none in the top 1,000 |
| Rotigotine | adverse reactions | none in the top 1,000 |
| Tafasitamab | adverse reactions | none in the top 1,000 |
| Tiopronin | adverse reactions | none in the top 1,000 |
| Triclabendazole | adverse reactions | none in the top 1,000 |
| Zopapogene imadenovec | adverse reactions | none in the top 1,000 |
| Sotalol | trial table | 179 |
| Quetiapine | patient leaflet | 2,714 |
| Olanzapine | patient leaflet | 1,236 |
| Leuprolide | patient leaflet | 930 |
| Alemtuzumab | patient leaflet | 256 |
| Voriconazole | patient leaflet | 85 |
| Selegiline | patient leaflet | 67 |
| Fluoxetine and olanzapine | patient leaflet | none in the top 1,000 |
| Iomeprol | patient leaflet | none in the top 1,000 |
| Tranylcypromine | patient leaflet | none in the top 1,000 |
Source: FDA drug labels via openFDA, read October 8, 2026; FAERS via openFDA, reports through July 30, 2026
Which of them have the most excessive sweating reports in FAERS?
Counts follow how widely a medicine is used and watched, and they are not a measure of how risky it is.
Source: FDA Adverse Event Reporting System (FAERS) via openFDA, reports through July 30, 2026; MedDRA preferred term “Hyperhidrosis”
What next?
- Side effects across medicines
- every reaction on PlainMeds
- Report a side effect to the FDA
- MedWatch