Side effects across medicines
Medicines whose labels list upper abdominal pain
264 medicines have an FDA label that names upper abdominal pain in its boxed warning, warnings, adverse reactions, trial table, patient leaflet or Drug Facts “stop use” warning (of the labels PlainMeds reads: each medicine's quoted label and up to eight more, by route and wording). Among them, the most FAERS reports of upper abdominal pain name apremilast (4,896), tocilizumab (4,478) and celecoxib (4,331), through July 30, 2026. A label lists what its studies and reports found, and a report does not show that a medicine caused the event.
Check it at the source: the FDA FAERS public dashboard; FDA labels on DailyMed.
Which medicines' labels list upper abdominal pain?
Ordered by where the label names it, the boxed warning first, then by FAERS reports. The first 150 of the 264 are below; every other one is on its medicine record. A medicine whose own indications name it, because it treats it, is not counted.
| Medicine | Where a label names it | FAERS reports of upper abdominal pain |
|---|---|---|
| Apremilast | adverse reactions | 4,896 |
| Tocilizumab | adverse reactions | 4,478 |
| Celecoxib | adverse reactions | 4,331 |
| Rituximab | adverse reactions | 3,892 |
| Lenalidomide | adverse reactions | 2,932 |
| Dulaglutide | adverse reactions | 2,473 |
| Treprostinil | adverse reactions (oral label) | 2,271 |
| Nintedanib | adverse reactions | 1,876 |
| Valsartan | adverse reactions | 1,680 |
| Pirfenidone | adverse reactions | 1,510 |
| Tadalafil | adverse reactions | 1,477 |
| Tramadol | adverse reactions | 1,417 |
| Mesalamine | adverse reactions | 1,352 |
| Buprenorphine | adverse reactions (transdermal label) | 1,285 |
| Octreotide | adverse reactions (oral label) | 1,270 |
| Voxelotor | adverse reactions | 1,171 |
| Atomoxetine | adverse reactions | 1,147 |
| Capecitabine | adverse reactions | 1,143 |
| Duloxetine | adverse reactions | 1,115 |
| Mepolizumab | adverse reactions | 1,087 |
| Dabigatran | adverse reactions | 1,008 |
| Omalizumab | adverse reactions | 982 |
| Linaclotide | adverse reactions | 942 |
| Cabozantinib | adverse reactions | 902 |
| Upadacitinib | adverse reactions | 899 |
| Fentanyl | adverse reactions (transdermal label) | 839 |
| Budesonide | adverse reactions (oral label) | 836 |
| Nilotinib | adverse reactions | 802 |
| Aripiprazole | adverse reactions | 780 |
| Olanzapine | adverse reactions | 737 |
| Levetiracetam | adverse reactions | 722 |
| Abaloparatide | adverse reactions | 716 |
| Risankizumab | adverse reactions | 695 |
| Deferasirox | adverse reactions | 673 |
| Sunitinib | adverse reactions | 630 |
| Moxifloxacin | adverse reactions (intravenous label) | 611 |
| Lenvatinib | adverse reactions | 597 |
| Risperidone | adverse reactions | 584 |
| Trastuzumab | adverse reactions | 552 |
| Cinacalcet | adverse reactions | 549 |
| Lisdexamfetamine | adverse reactions | 539 |
| Fulvestrant | adverse reactions | 535 |
| Sodium oxybate | adverse reactions | 513 |
| Sorafenib | adverse reactions | 496 |
| Teduglutide | adverse reactions | 494 |
| Elexacaftor and ivacaftor and tezacaftor | adverse reactions | 474 |
| Bortezomib | adverse reactions | 433 |
| Patiromer | adverse reactions | 426 |
| Mycophenolic acid | adverse reactions | 418 |
| Imatinib | adverse reactions | 416 |
| Fluticasone and vilanterol | adverse reactions | 413 |
| Carbidopa and levodopa | adverse reactions (enteral label) | 381 |
| Rifaximin | adverse reactions | 371 |
| Venetoclax | adverse reactions | 357 |
| Lanreotide | adverse reactions | 311 |
| Bupropion and naltrexone | adverse reactions | 267 |
| Voclosporin | adverse reactions | 264 |
| Armodafinil | adverse reactions | 249 |
| Bosutinib | adverse reactions | 246 |
| Axitinib | adverse reactions | 243 |
| Pertuzumab | adverse reactions | 241 |
| Fluvastatin | adverse reactions | 228 |
| Naloxegol | adverse reactions | 228 |
| Hydrocodone | adverse reactions | 220 |
| Sapropterin | adverse reactions | 217 |
| Ketoconazole | adverse reactions (oral label) | 212 |
| Eluxadoline | adverse reactions | 210 |
| Olaparib | adverse reactions | 199 |
| Trametinib | adverse reactions | 194 |
| Ropinirole | adverse reactions | 178 |
| Lurasidone | adverse reactions | 165 |
| Fesoterodine | adverse reactions | 152 |
| Vilazodone | adverse reactions | 152 |
| Rivastigmine | adverse reactions | 143 |
| Ivacaftor and lumacaftor | adverse reactions | 138 |
| Deflazacort | adverse reactions | 137 |
| Tucatinib | adverse reactions | 136 |
| Ibandronate | adverse reactions | 131 |
| Guselkumab | adverse reactions | 121 |
| Ozanimod | adverse reactions | 106 |
| Pegvaliase | adverse reactions | 102 |
| Ascorbic acid, polyethylene glycol 3350 and 4 other ingredients | adverse reactions | 101 |
| Crizotinib | adverse reactions | 101 |
| Fostamatinib | adverse reactions | 98 |
| Guanfacine | adverse reactions | 98 |
| Neratinib | adverse reactions | 97 |
| Binimetinib | adverse reactions | 95 |
| Azacitidine | adverse reactions | 94 |
| Abacavir and dolutegravir and lamivudine | adverse reactions | none in the top 1,000 |
| Abemaciclib | adverse reactions | none in the top 1,000 |
| Abrocitinib | adverse reactions | none in the top 1,000 |
| Acoramidis | adverse reactions | none in the top 1,000 |
| Aflibercept | adverse reactions (intravenous label) | none in the top 1,000 |
| Alectinib | adverse reactions | none in the top 1,000 |
| Almotriptan | adverse reactions | none in the top 1,000 |
| Alosetron | adverse reactions | none in the top 1,000 |
| Amoxicillin and omeprazole and rifabutin | adverse reactions | none in the top 1,000 |
| Anhydrous citric acid and magnesium oxide and sodium picosulfate | adverse reactions | none in the top 1,000 |
| Anidulafungin | adverse reactions | none in the top 1,000 |
| Asciminib | adverse reactions | none in the top 1,000 |
| Ascorbic acid, peg 3350 and 4 other ingredients | adverse reactions | none in the top 1,000 |
| Asenapine | adverse reactions | none in the top 1,000 |
| Asparaginase | adverse reactions | none in the top 1,000 |
| Atazanavir and cobicistat | adverse reactions | none in the top 1,000 |
| Avacopan | adverse reactions | none in the top 1,000 |
| Avapritinib | adverse reactions | none in the top 1,000 |
| Avelumab | adverse reactions | none in the top 1,000 |
| Avibactam and aztreonam | adverse reactions | none in the top 1,000 |
| Avibactam and ceftazidime | adverse reactions | none in the top 1,000 |
| Azelastine and fluticasone | adverse reactions | none in the top 1,000 |
| Balsalazide | adverse reactions | none in the top 1,000 |
| Baricitinib | adverse reactions | none in the top 1,000 |
| Bazedoxifene and estrogens conjugated | adverse reactions | none in the top 1,000 |
| Bedaquiline | adverse reactions | none in the top 1,000 |
| Belatacept | adverse reactions | none in the top 1,000 |
| Belumosudil | adverse reactions | none in the top 1,000 |
| Bendamustine | adverse reactions | none in the top 1,000 |
| Berotralstat | adverse reactions | none in the top 1,000 |
| Bremelanotide | adverse reactions | none in the top 1,000 |
| Brigatinib | adverse reactions | none in the top 1,000 |
| Brincidofovir | adverse reactions | none in the top 1,000 |
| Bulevirtide | adverse reactions | none in the top 1,000 |
| Bupropion and dextromethorphan | adverse reactions | none in the top 1,000 |
| Cabazitaxel | adverse reactions | none in the top 1,000 |
| Cabotegravir | adverse reactions | none in the top 1,000 |
| Cabotegravir and rilpivirine | adverse reactions | none in the top 1,000 |
| Carfilzomib | adverse reactions | none in the top 1,000 |
| Cariprazine | adverse reactions | none in the top 1,000 |
| Casimersen | adverse reactions | none in the top 1,000 |
| Caspofungin | adverse reactions | none in the top 1,000 |
| Cedazuridine and decitabine | adverse reactions | none in the top 1,000 |
| Ceftobiprole medocaril | adverse reactions | none in the top 1,000 |
| Ceftolozane and tazobactam | adverse reactions | none in the top 1,000 |
| Cemiplimab | adverse reactions | none in the top 1,000 |
| Ceritinib | adverse reactions | none in the top 1,000 |
| Chenodiol | adverse reactions | none in the top 1,000 |
| Clofarabine | adverse reactions | none in the top 1,000 |
| Cobicistat | adverse reactions | none in the top 1,000 |
| Crizanlizumab | adverse reactions | none in the top 1,000 |
| Cytarabine and daunorubicin | adverse reactions | none in the top 1,000 |
| Daprodustat | adverse reactions | none in the top 1,000 |
| Daratumumab and hyaluronidase | adverse reactions | none in the top 1,000 |
| Decitabine | adverse reactions | none in the top 1,000 |
| Dextroamphetamine | adverse reactions (transdermal label) | none in the top 1,000 |
| Dinutuximab | adverse reactions | none in the top 1,000 |
| Dolutegravir | adverse reactions | none in the top 1,000 |
| Dolutegravir and lamivudine | adverse reactions | none in the top 1,000 |
| Dolutegravir and rilpivirine | adverse reactions | none in the top 1,000 |
| Doravirine | adverse reactions | none in the top 1,000 |
| Doravirine and islatravir | adverse reactions | none in the top 1,000 |
Source: FDA drug labels via openFDA, read October 8, 2026; FAERS via openFDA, reports through July 30, 2026
Which of them have the most upper abdominal pain reports in FAERS?
Counts follow how widely a medicine is used and watched, and they are not a measure of how risky it is.
Source: FDA Adverse Event Reporting System (FAERS) via openFDA, reports through July 30, 2026; MedDRA preferred term “Abdominal Pain Upper”
What next?
- Side effects across medicines
- every reaction on PlainMeds
- Report a side effect to the FDA
- MedWatch