Prescription medicine
Anhydrous citric acid and magnesium oxide and sodium picosulfate Brand names: Clenpiq
Anhydrous citric acid and magnesium oxide and sodium picosulfate (Clenpiq) is a prescription medicine. No generic is listed; pharmacies paid $0.518 per mL (Clenpiq 175 mL solution) in the October 7, 2026 NADAC survey.
- No generic listed
Check it at the source: the anhydrous citric acid and magnesium oxide and sodium picosulfate FDA label on DailyMed (effective April 15, 2026); every anhydrous citric acid and magnesium oxide and sodium picosulfate label on DailyMed.
Highlights of the record
FDA label of April 15, 2026; NDC Directory, Drugs@FDA and Orange Book, October 8, 2026; NADAC October 7, 2026
Used for
From the label: indications and usageCLENPIQ is indicated for cleansing of the colon as a preparation for colonoscopy in adults and pediatric patients 9 years of age and older.
Forms and strengths
- 10 mg/175ml / 3.5 g/175ml / 12 g/175ml
Liquid.
On the market
- Generic approvals
- No generic approved
- Labelers listed (NDC)
- 1 of which 0 under generic applications, 1 under brand applications, repackagers included
Supply and safety
- Pharmacy cost (NADAC)
- $0.518 per mL Clenpiq 175 mL solution
- Shortage (FDA)
- No current entry
- Recalls by its makers (FDA)
- No recall recorded
- FAERS reports
- 722 through July 30, 2026
What is anhydrous citric acid and magnesium oxide and sodium picosulfate used for?
From the label: indications and usageCLENPIQ is indicated for cleansing of the colon as a preparation for colonoscopy in adults and pediatric patients 9 years of age and older. CLENPIQ ® is a combination of sodium picosulfate, a stimulant laxative, and magnesium oxide and anhydrous citric acid, which form magnesium citrate, an osmotic laxative, indicated for cleansing of the colon as a preparation for colonoscopy in adults and pediatric patients ages 9 years and older.
FDA pharmacologic class: Anti-coagulant, Calculi Dissolution Agent, Osmotic Laxative and Stimulant Laxative.
Source: FDA drug label (CLENPIQ), Ferring Pharmaceuticals Inc., effective April 15, 2026 (SPL set e95fff66-4ec0-4001-a727-33e66a5ec7d5), via openFDA; the full label on DailyMed
What does the patient leaflet for anhydrous citric acid and magnesium oxide and sodium picosulfate say first?
The FDA-approved Medication Guide or Patient Information that comes with the medicine, in its own words.
From the patient leaflet: What is the most important information I should know about CLENPIQ?CLENPIQ and other bowel preparations can cause serious side effects, including: Serious loss of body fluid (dehydration) and changes in blood salts (electrolytes) in your blood. These changes can cause: abnormal heartbeats that can cause death. seizures. This can happen even if you have never had a seizure. kidney problems. fainting. Your chance of having fluid loss and changes in blood salts with CLENPIQ is higher if you: have heart problems have kidney problems take water pills or non-steroidal anti-inflammatory drugs (NSAIDS) Tell your healthcare provider right away if you have any of these symptoms of a loss of too much body fluid (dehydration) while taking CLENPIQ: vomiting urinating less often than normal dizziness headache See "What are the possible side effects of CLENPIQ?" for more information about side effects.
From the patient leaflet: How should I store CLENPIQ?Store CLENPIQ at room temperature, between 68° to 77°F (20° to 25°C). Do not put CLENPIQ in the refrigerator or freezer. Keep CLENPIQ and all medicines out of the reach of children.
Source: FDA drug label (CLENPIQ), Ferring Pharmaceuticals Inc., effective April 15, 2026 (SPL set e95fff66-4ec0-4001-a727-33e66a5ec7d5), via openFDA; the full label on DailyMed
Is there a generic for anhydrous citric acid and magnesium oxide and sodium picosulfate (Clenpiq)?
No generic anhydrous citric acid and magnesium oxide and sodium picosulfate is approved (Drugs@FDA, October 8, 2026).
Source: Drugs@FDA, FDA NDC Directory and the Orange Book (openFDA bulk files, October 8, 2026)
What do pharmacies pay for anhydrous citric acid and magnesium oxide and sodium picosulfate (Clenpiq)?
In CMS's NADAC survey of October 7, 2026, pharmacies paid $0.518 per mL (Clenpiq 175 mL solution), up 4% from $0.498 on October 8, 2025. The chart's scale runs from the lowest to the highest price shown, not from zero. NADAC is what retail pharmacies paid their wholesalers, per unit, in CMS's monthly survey; what a patient pays depends on insurance and the pharmacy.
- Clenpiq 175 mL solution (brand)
| Strength and form | Brand or generic | Pharmacy cost | 30 tablets, or one pen or vial | 12-month change |
|---|---|---|---|---|
| Clenpiq 175 mL solution | Brand | $0.518 per mL | n/a | +4% |
Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price
What does the anhydrous citric acid and magnesium oxide and sodium picosulfate label say about other medicines?
The anhydrous citric acid and magnesium oxide and sodium picosulfate label names 4 other medicines in its interaction, contraindication or warning sections. The sentences are the labels' own; a label lists what its studies and reports found, not every interaction.
| Medicine named | Section | What the label says |
|---|---|---|
| Chlorpromazine | drug interactions | Administer tetracycline and fluoroquinolone antibiotics [see Drug Interactions (7.3) ], iron, digoxin, chlorpromazine, and penicillamine at least 2 hours before and not less than 6 hours after administration of CLENPIQ to avoid chelation with magnesium. |
| Digoxin | drug interactions | Administer tetracycline and fluoroquinolone antibiotics [see Drug Interactions (7.3) ], iron, digoxin, chlorpromazine, and penicillamine at least 2 hours before and not less than 6 hours after administration of CLENPIQ to avoid chelation with magnesium. |
| Penicillamine | drug interactions | Administer tetracycline and fluoroquinolone antibiotics [see Drug Interactions (7.3) ], iron, digoxin, chlorpromazine, and penicillamine at least 2 hours before and not less than 6 hours after administration of CLENPIQ to avoid chelation with magnesium. |
| Tetracycline | drug interactions | Administer tetracycline and fluoroquinolone antibiotics [see Drug Interactions (7.3) ], iron, digoxin, chlorpromazine, and penicillamine at least 2 hours before and not less than 6 hours after administration of CLENPIQ to avoid chelation with magnesium. |
Check anhydrous citric acid and magnesium oxide and sodium picosulfate against other medicines
Source: FDA drug label (CLENPIQ), Ferring Pharmaceuticals Inc., effective April 15, 2026 (SPL set e95fff66-4ec0-4001-a727-33e66a5ec7d5), via openFDA; the full label on DailyMed
What do FAERS reports show for anhydrous citric acid and magnesium oxide and sodium picosulfate?
The FDA Adverse Event Reporting System holds 722 reports that list anhydrous citric acid and magnesium oxide and sodium picosulfate among the medicines taken, through July 30, 2026, each a report of something that happened, not proof the medicine caused it; 2 are coded as a death and 40 as a hospital stay. Counts follow how widely a medicine is used and watched, and they are not a measure of how risky it is.
Reports received each year
The most reported reactions
Source: FDA Adverse Event Reporting System (FAERS) via openFDA, reports through July 30, 2026
What next?
- Other anti-coagulants
- the pharmacologic class, with prices and generics
- Anhydrous citric acid and magnesium oxide and sodium picosulfate side effects
- the label's list beside FAERS reports
- Check an interaction
- what two or more labels say about each other