Prescription medication · Echinocandin Antifungal
anidulafungin
Also sold as Eraxis. Eraxis treats candidemia and other Candida infections, like intra-abdominal abscesses and peritonitis.
Data updated 2026-05-15
- 1,527
- FDA reportsRarely reported
- 4
- InteractionsFew interactions
- Rx
- Availability
What the data shows
anidulafungin (Eraxis) is a prescription Echinocandin Antifungal, among the least-reported drugs the FDA tracks (1,527 FDA reports), with 4 documented drug interactions.
Reporting volume reflects how widely a drug is used and studied, not how dangerous it is, a FAERS report documents a temporal association, never proof of cause.
anidulafungin (Eraxis) is a prescription Echinocandin Antifungal. Eraxis treats candidemia and other Candida infections, like intra-abdominal abscesses and peritonitis.
Eraxis is an antifungal medicine. It treats certain Candida infections in your body.
Verify with FDA → · CMS NADAC pricing →
What it does
Eraxis treats candidemia and other Candida infections, like intra-abdominal abscesses and peritonitis.
Common side effects
Low potassium levels, Nausea, Diarrhea
Key warnings
Eraxis can cause liver problems.
The sections below are summarized in plain English from anidulafungin's FDA-approved prescribing information. They describe what the official label says, and are not personal medical advice.
How It Works
Eraxis belongs to a class of drugs called echinocandins. It works by stopping the growth of the fungus Candida. It does this by blocking a key part of the fungal cell wall.
How to Take It
Eraxis is given to you through a vein (IV). The medicine is mixed with sterile water and then with a solution like dextrose or saline. The IV should be given slowly, at a rate no faster than 1.1 mg per minute. Your doctor will decide the right dose and how long you need treatment.
This is a plain-language summary of anidulafungin's FDA labeling, not individualized dosing advice. Ask a pharmacist or prescriber before changing how you take this medication.
Pregnancy & Breastfeeding
Eraxis may harm your unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. It is not known if Eraxis passes into breast milk. Talk to your doctor about the risks and benefits of breastfeeding while taking Eraxis.
This is a plain-language summary of anidulafungin's FDA labeling, not individualized advice. Ask a pharmacist or prescriber about pregnancy or breastfeeding on this medication.
Missed Dose
Call your doctor right away if you miss a dose of Eraxis. They will tell you when to get your next dose.
This is a plain-language summary of anidulafungin's FDA labeling, not individualized advice. Ask a pharmacist or prescriber what to do about your specific missed dose.
Storage
Keep Eraxis vials in the refrigerator between 36°F and 46°F (2°C – 8°C). Do not freeze.
Side Effects (from patient reports)
Based on 1,527 FDA adverse event reports.
Most-reported reactions
Adverse reactions in FAERS for anidulafungin, by number of reports
- Many organs stop working right
Many organs stop working right
171 reports
- Dangerous drop in blood pressure due to infection
Dangerous drop in blood pressure due to infection
127 reports
- Blood infection
Blood infection
115 reports
- Lung infection
Lung infection
94 reports
- Fever
Fever
90 reports
- Yeast infection
Yeast infection
89 reports
- Death
Death
81 reports
- Low white blood cell count
Low white blood cell count
78 reports
- Kidney failure 68
Kidney failure
68 reports
- Lung failure 63
Lung failure
63 reports
What this shows Bars show how often each reaction was reported, not how likely it is to happen, a report records a temporal association, never proof that the drug caused it.
Reports over time
Adverse-event reports filed for anidulafungin each year to the FDA Adverse Event Reporting System (FAERS).
Year-to-year volume tracks usage, prescribing, and scrutiny, not a change in per-patient risk. Source: FDA FAERS.
Where anidulafungin sits
anidulafungin has more FDA adverse-event reports than 10% of the drugs FAERS tracks. A high position reflects how widely a drug is used and watched, not how dangerous it is.
Percentile across all drugs PlainMeds tracks by FAERS report volume. The dot is anidulafungin; the line is the median (50th percentile).
FDA Adverse Event Report Analysis
Detailed analysis of 1,527 reports from the FDA Adverse Event Reporting System (FAERS). Reports span 2006–2025.
Total Reports
1,527
Reports Mentioning Death
665
43.5% of reports — not proof of cause
Hospitalization Reports
741
Top Indication
Product Used For Unknown Indication
Gender Distribution
Age Distribution
Most Reported Adverse Reactions (FAERS)
| # | Reaction | Reports |
|---|---|---|
| 2 | MULTIPLE ORGAN DYSFUNCTION SYNDROME | 171 |
| 4 | SEPTIC SHOCK | 127 |
| 5 | SEPSIS | 115 |
| 6 | PNEUMONIA | 94 |
| 7 | PYREXIA | 90 |
| 8 | CANDIDA INFECTION | 89 |
| 9 | DEATH | 81 |
| 10 | NEUTROPENIA | 78 |
| 11 | RENAL FAILURE | 68 |
| 12 | RESPIRATORY FAILURE | 63 |
| 13 | CONDITION AGGRAVATED | 59 |
| 14 | DRUG RESISTANCE | 58 |
| 15 | HYPOTENSION | 57 |
| 16 | ACUTE KIDNEY INJURY | 56 |
| 17 | THROMBOCYTOPENIA | 56 |
Reactions in Death Reports
Reactions in Hospitalization Reports
Source: FDA FAERS (Adverse Event Reporting System) FDA FAERS (Adverse Event Reporting System) Reports are voluntary and do not establish causation
Serious Warnings
Eraxis can cause liver problems. Your doctor should check your liver function while you are taking Eraxis. Allergic reactions, including shock, can happen. Tell your doctor right away if you have any signs of an allergic reaction, like rash, hives, flushing, itching, trouble breathing, or low blood pressure. Eraxis contains fructose. If you have hereditary fructose intolerance, you should not take Eraxis.
Known Drug Interactions
7 DRUG INTERACTIONS 7.1 Cyclosporine Administration of multiple doses of anidulafungin and cyclosporine to healthy subjects resulted in no significant alteration in the steady state pharmacokinetics of either drug. No dosage adjustment of cyclosporine or anidulafungin is needed when the two drugs are co-administered [see Clinical Pharmacology (12.3) ] .
Mechanism: These two drugs do not change how the body processes or breaks down each other. They can be used together without affecting the amount of medicine in your blood.
What to do: No dose changes are needed when taking these two medications at the same time.
7.4 Rifampin Administration of multiple doses of anidulafungin and rifampin to patients resulted in no significant alteration in the steady state pharmacokinetics of anidulafungin. No dosage adjustment of anidulafungin is needed when it is co-administered with rifampin [see Clinical Pharmacology (12.3) ] .
Mechanism: Taking these medicines together does not change the level of either drug in your system. They do not interfere with how the body handles the medication.
What to do: You do not need to adjust your dosage when these drugs are used together.
7.2 Voriconazole Administration of multiple doses of anidulafungin and voriconazole to healthy subjects resulted in no significant alteration in the steady state pharmacokinetics of either drug. No dosage adjustment of voriconazole or anidulafungin is needed when the two drugs are co-administered [see Clinical Pharmacology (12.3) ] .
Mechanism: These drugs do not affect how the body uses or removes either medication. Their levels in the blood stay the same when they are taken together.
What to do: No dosage adjustments are necessary for either drug when used together.
7.5 Amphotericin B Liposome for Injection Administration of multiple doses of anidulafungin and liposomal amphotericin B to patients resulted in no significant alteration in the steady state pharmacokinetics of anidulafungin. No dosage adjustment of anidulafungin is needed when it is co-administered with liposomal amphotericin B [see Clinical Pharmacology (12.3) ] .
Mechanism: These medications do not interfere with each other's levels in the body. They do not change how the body processes the medicine.
What to do: No dose adjustment is required when taking these two medications together.
This is a plain-language summary of interactions documented in FDA labeling, not individualized advice. Ask a pharmacist or prescriber before combining medications.
Common Questions
How long will I need to take Eraxis?
Can Eraxis be given to children?
What should I tell my doctor before taking Eraxis?
Can I take other medicines with Eraxis?
What is a loading dose?
How will Eraxis be given to me?
What if I have side effects from Eraxis?
Can Eraxis cure my infection?
What does 'not approved' mean for Esophageal candidiasis in children?
What is Candida?
What are the common side effects of anidulafungin?
Does anidulafungin interact with other medications?
What drug class is anidulafungin?
Is anidulafungin safe during pregnancy?
Related Medications in Echinocandin Antifungal
Other drugs grouped near anidulafungin - same-class peers and common alternatives.
acyclovir
Zovirax
Acyclovir is an antiviral medicine.
Compare with anidulafungin →
albendazole
Albenza
Albendazole is a medicine that fights parasites.
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amphotericin B
Ambisome, Fungizone
Amphotericin B liposome is an antifungal medicine.
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atovaquone/proguanil
Malarone
Malarone is a drug used to prevent and treat malaria.
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baloxavir marboxil
Xofluza
Xofluza is an antiviral medicine that can treat the flu.
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What the FDA Data Shows for anidulafungin
The FDA label for anidulafungin (sold under brand names such as Eraxis) classifies it as a prescription-only medication in the Echinocandin Antifungal class. Eraxis treats candidemia and other Candida infections, like intra-abdominal abscesses and peritonitis. Official labeling lists 17 commonly reported side effects, including Low potassium levels, Nausea, Diarrhea.
Post-market surveillance from the FDA Adverse Event Reporting System (FAERS) captures real-world experience. For this drug, FAERS contains 1,527 voluntary reports. The database also lists 4 documented drug interactions derived from FDA labeling, with the top-flagged interaction rated minor severity. Acquisition-cost data is surveyed weekly by CMS and updated as manufacturers report changes.
Report counts do not establish causation, a FAERS entry documents a temporal association, not proof that the drug produced the outcome. Widely prescribed medications naturally accumulate more reports than niche therapies, so raw totals must be interpreted alongside total exposure. Shortage status, recall history, and patent information further shape supply and switching decisions. This page summarizes public FDA data for educational purposes only and is not a substitute for professional medical advice, always consult a licensed healthcare provider before starting, stopping, or changing any medication.
Data Sources
Drug labeling: FDA Drug Labels (SPL/DailyMed). Adverse events: FDA Adverse Event Reporting System (FAERS).
FAERS reports are voluntary and do not establish causation. Drug interactions are derived from FDA labeling and clinical references. Always consult a healthcare professional before making medication decisions.
Last updated: August 19, 2025
Read our methodology - how this data is sourced, computed, and verified.
Data currency: FDA FAERS adverse-event reports through 2025, CMS NADAC acquisition-cost pricing effective December 2024, compiled and last refreshed May 2026. See our methodology for per-source dates and refresh cadence. Spot a figure that looks wrong? Report a correction.
All federal data sources used on this page
- FDA Orange Book - approved drug products with therapeutic equivalence. accessdata.fda.gov/cder/ob
- FDA DailyMed - NIH-hosted drug labeling for FDA-approved meds. dailymed.nlm.nih.gov
- FDA Adverse Event Reporting System (FAERS) - post-marketing safety surveillance. fda.gov/drugs/faers
- NLM RxNorm - standardized clinical drug nomenclature. nlm.nih.gov/research/umls/rxnorm
- CMS Medicare Part B Drug Average Sales Price Files - federal drug pricing data. cms.gov/medicare/part-b-drugs/asp
- FDA Drug Shortages Database - current and resolved drug shortage tracking. accessdata.fda.gov/drugshortages