Trandolapril and Furosemide Interaction
Drug interaction information between Trandolapril and Furosemide.
Trandolapril and Furosemide have a documented minor interaction in FDA labeling.
FDA drug labeling documents a minor-severity interaction between Trandolapril and Furosemide. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
Studies show that these two medications do not interfere with each other in the body. They can be processed by the body at the same time without issues.
FDA Label Information
Other No clinically significant pharmacokinetic interaction has been found between trandolaprilat and food, cimetidine, digoxin, or furosemide.
Trandolapril Also Interacts With
- Aliskiren major
- Spironolactone moderate
- Lithium moderate
- Amiloride moderate
- Warfarin minor
Furosemide Also Interacts With
- Dutasteride major
- Dutasteride/Tamsulosin major
- Tamsulosin major
- Cyclosporine moderate
- Lithium moderate
Frequently Asked Questions
What SPL severity band is on file for Trandolapril + Furosemide?
Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Furosemide has 36 labeled pairs on file vs Trandolapril's 8. In the minor band specifically: Trandolapril has 4 (also Warfarin, Digoxin, Cimetidine); Furosemide has 29 (also Methotrexate, Norepinephrine, Ethacrynic Acid, Indomethacin).
What mechanism field is on file for Trandolapril and Furosemide?
Studies show that these two medications do not interfere with each other in the body. They can be processed by the body at the same time without issues.
Furosemide carries more major-labeled pairs than Trandolapril
SPL source-record counts only. This page's band is minor · classes on file: Trandolapril (ACE Inhibitor); Furosemide (Loop Diuretic).
Furosemide has 3 major-labeled pairs vs Trandolapril's 1. This page itself is in the minor band, not the major band.
1 major · 3 moderate · 4 minor · 8 total
- Other minor peers for Trandolapril
- Warfarin
- Digoxin
- Cimetidine
3 major · 4 moderate · 29 minor · 36 total
- Other minor peers for Furosemide
- Methotrexate
- Norepinephrine
- Ethacrynic Acid
- Indomethacin
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.