Furosemide and Dutasteride Interaction

Drug interaction information between Furosemide and Dutasteride.

Furosemide and Dutasteride have a documented major interaction in FDA labeling.

FDA drug labeling documents a major-severity interaction between Furosemide and Dutasteride. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.

Drug A

Furosemide

Loop Diuretic

Drug B

Dutasteride

5-Alpha Reductase Inhibitor

How They Interact

Furosemide slightly lowers the amount of the other drug in your blood, but the effect is too small to matter.

FDA Label Information

7.5 Furosemide Tamsulosin Tamsulosin had no effect on the pharmacodynamics (excretion of electrolytes) of furosemide. While furosemide produced an 11% to 12% reduction in tamsulosin hydrochloride C max and AUC, these changes are expected to be clinically insignificant and do not require adjustment of the dose of tamsulosin [see Clinical Pharmacology ( 12.3 ) ] .

Dutasteride Also Interacts With

View all Dutasteride interactions →

Frequently Asked Questions

What SPL severity band is on file for Furosemide + Dutasteride?

Compiled FDA labeling labels this pair major. That is a source-record field, not an individual medication-combination decision.

Which drug in this pair has the larger labeled-interaction portfolio?

Furosemide has 36 labeled pairs on file vs Dutasteride's 16. In the major band specifically: Furosemide has 3 (also Dutasteride/Tamsulosin, Tamsulosin); Dutasteride has 1.

What mechanism field is on file for Furosemide and Dutasteride?

Furosemide slightly lowers the amount of the other drug in your blood, but the effect is too small to matter.

Furosemide carries more major-labeled pairs than Dutasteride

SPL source-record counts only. This page's band is major · classes on file: Furosemide (Loop Diuretic); Dutasteride (5-Alpha Reductase Inhibitor).

Furosemide has 3 major-labeled pairs vs Dutasteride's 1.

Furosemide

3 major · 4 moderate · 29 minor · 36 total

Dutasteride

1 major · 2 moderate · 13 minor · 16 total

Dutasteride has no other major-band peer in this dataset besides Furosemide.

Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.