What the FDA labels say about taking them together
Cyclosporine and furosemide
Furosemide's FDA label of September 30, 2025 names cyclosporine in its drug interactions section; the cyclosporine labels PlainMeds reads (4) do not name furosemide. The furosemide label: “Cyclosporine Increased risk of gouty arthritis secondary to furosemide-induced hyperuricemia and cyclosporine impairment of renal urate excretion. Monitor serum urate levels.”
Check it at the source: the cyclosporine FDA label on DailyMed (effective August 10, 2026, Novartis Pharmaceuticals Corporation); the furosemide FDA label on DailyMed (effective September 30, 2025, Validus Pharmaceuticals LLC).
What does the cyclosporine label say about furosemide?
Cyclosporine's label (effective August 10, 2026) and its 3 other brand-application labels do not name furosemide in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Neoral), Novartis Pharmaceuticals Corporation, effective August 10, 2026 (SPL set 94461af3-11f1-4670-95d4-2965b9538ae3), via openFDA; the full label on DailyMed
What does the furosemide label say about cyclosporine?
Furosemide label, drug interactionsConcomitant use of cyclosporine and LASIX is associated with increased risk of gouty arthritis secondary to LASIX-induced hyperurecemia and cyclosporine impairment of renal urate excretion.
Furosemide label (Hikma Pharmaceuticals USA Inc., March 10, 2025), drug interactionsCyclosporine Increased risk of gouty arthritis secondary to furosemide-induced hyperuricemia and cyclosporine impairment of renal urate excretion. Monitor serum urate levels.
Source: FDA drug label (Furosemide, NDA018267), Hikma Pharmaceuticals USA Inc., effective March 10, 2025 (SPL set ddfc41a9-37d4-49c1-bbf3-969a98cd649c), via openFDA
Source: FDA drug label (Lasix), Validus Pharmaceuticals LLC, effective September 30, 2025 (SPL set 2c9b4d8f-0770-482d-a9e6-9c616a440b1a), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Cyclosporine | Furosemide | |
|---|---|---|
| Labeled for | Organ transplant rejection, Rheumatoid arthritis | Heart failure, High blood pressure, Edema (fluid retention) |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $1.04 per unit 0.05% eye emulsion | $0.490 per mL 20 mg/2 mL vial |
| Shortage now | No current entry | In shortage |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once