Side effects across medicines

Medicines whose labels list dry skin

199 medicines have an FDA label that names dry skin in its boxed warning, warnings, adverse reactions, trial table, patient leaflet or Drug Facts “stop use” warning (of the labels PlainMeds reads: each medicine's quoted label and up to eight more, by route and wording). Among them, the most FAERS reports of dry skin name adapalene (45,426), omeprazole (2,870) and isotretinoin (2,425), through July 30, 2026. A label lists what its studies and reports found, and a report does not show that a medicine caused the event.

Check it at the source: the FDA FAERS public dashboard; FDA labels on DailyMed.

Which medicines' labels list dry skin?

Ordered by where the label names it, the boxed warning first, then by FAERS reports. The first 150 of the 199 are below; every other one is on its medicine record. A medicine whose own indications name it, because it treats it, is not counted.

Medicine	Where a label names it	FAERS reports of dry skin
Palovarotene	warnings and precautions	none in the top 1,000
Adapalene	adverse reactions	45,426
Omeprazole	adverse reactions	2,870
Isotretinoin	adverse reactions	2,425
Lenalidomide	adverse reactions	2,336
Palbociclib	adverse reactions	1,432
Cabozantinib	adverse reactions	1,309
Peginterferon alfa 2a	adverse reactions	1,203
Ribavirin	adverse reactions	1,088
Pregabalin	adverse reactions	916
Sunitinib	adverse reactions	773
Tacrolimus	adverse reactions (topical label)	741
Citalopram	adverse reactions	674
Ribociclib	adverse reactions	663
Panitumumab	adverse reactions	656
Celecoxib	adverse reactions	550
Sorafenib	adverse reactions	509
Cyclosporine	adverse reactions	508
Fulvestrant	adverse reactions	494
Bevacizumab	adverse reactions	461
Tiotropium	adverse reactions	450
Everolimus	adverse reactions	439
Cetuximab	adverse reactions	425
Fluorouracil	adverse reactions	414
Lamotrigine	adverse reactions	412
Lapatinib ditosylate	adverse reactions	397
Pomalidomide	adverse reactions	371
Oxaliplatin	adverse reactions	331
Nilotinib	adverse reactions	319
Mirtazapine	adverse reactions	287
Trametinib	adverse reactions	280
Olanzapine	adverse reactions	262
Mupirocin	adverse reactions	240
Pertuzumab	adverse reactions	238
Enzalutamide	adverse reactions	236
Axitinib	adverse reactions	220
Ripretinib	adverse reactions	220
Metronidazole	adverse reactions (topical label)	218
Afatinib	adverse reactions	199
Erlotinib	adverse reactions	193
Gefitinib	adverse reactions	193
Dabrafenib	adverse reactions	191
Natalizumab	adverse reactions	179
Leuprolide	adverse reactions	178
Imatinib	adverse reactions	169
Paroxetine	adverse reactions	163
Vemurafenib	adverse reactions	155
Oxybutynin	adverse reactions	150
Ponatinib	adverse reactions	148
Risperidone	adverse reactions	145
Pazopanib	adverse reactions	141
Varenicline	adverse reactions	137
Buspirone	adverse reactions	136
Alpelisib	adverse reactions	129
Acitretin	adverse reactions	126
Enfortumab vedotin	adverse reactions	123
Divalproex	adverse reactions	116
Thalidomide	adverse reactions	103
Brensocatib	adverse reactions	96
Testosterone	adverse reactions (transdermal label)	96
Calcium chloride, icodextrin, magnesium chloride, sodium chloride and sodium lactate	adverse reactions	91
Sirolimus	adverse reactions (topical label)	82
Goserelin	adverse reactions	81
Talquetamab	adverse reactions	78
Medroxyprogesterone	adverse reactions (intramuscular label)	73
Encorafenib	adverse reactions	72
Glatiramer	adverse reactions	65
Eszopiclone	adverse reactions	64
Glycopyrrolate	adverse reactions	60
Binimetinib	adverse reactions	59
Ammonium lactate	adverse reactions	57
Halobetasol	adverse reactions	53
Bicalutamide	adverse reactions	52
Neratinib	adverse reactions	52
Niacin	adverse reactions	51
Calcipotriene	adverse reactions	49
Voriconazole	adverse reactions	46
Glycopyrronium	adverse reactions	43
Tazarotene	adverse reactions	42
Vandetanib	adverse reactions	41
Temozolomide	adverse reactions	39
Selumetinib	adverse reactions	38
Avutometinib and defactinib	adverse reactions	36
Olodaterol and tiotropium	adverse reactions	35
Cobimetinib	adverse reactions	34
Amivantamab	adverse reactions	32
Azelaic acid	adverse reactions	31
Erdafitinib	adverse reactions	31
Acamprosate	adverse reactions	none in the top 1,000
Adagrasib	adverse reactions	none in the top 1,000
Amivantamab and hyaluronidase	adverse reactions	none in the top 1,000
Amoxicillin and clarithromycin and lansoprazole	adverse reactions	none in the top 1,000
Amoxicillin and omeprazole and rifabutin	adverse reactions	none in the top 1,000
Amphotericin b	adverse reactions	none in the top 1,000
Arformoterol	adverse reactions	none in the top 1,000
Arsenic trioxide	adverse reactions	none in the top 1,000
Asparaginase	adverse reactions	none in the top 1,000
Atropine and pralidoxime	adverse reactions	none in the top 1,000
Azacitidine	adverse reactions	none in the top 1,000
Bedaquiline	adverse reactions	none in the top 1,000
Bendamustine	adverse reactions	none in the top 1,000
Benzoyl peroxide and clindamycin	adverse reactions	none in the top 1,000
Bevacizumab-maly	adverse reactions	none in the top 1,000
Bexarotene	adverse reactions	none in the top 1,000
Brentuximab vedotin	adverse reactions	none in the top 1,000
Brigatinib	adverse reactions	none in the top 1,000
Caffeine	adverse reactions	none in the top 1,000
Capivasertib	adverse reactions	none in the top 1,000
Cefpodoxime	adverse reactions	none in the top 1,000
Cevimeline	adverse reactions	none in the top 1,000
Cidofovir	adverse reactions	none in the top 1,000
Clindamycin and tretinoin	adverse reactions	none in the top 1,000
Clomipramine	adverse reactions	none in the top 1,000
Dacomitinib	adverse reactions	none in the top 1,000
Daraxonrasib	adverse reactions	none in the top 1,000
Darifenacin	adverse reactions	none in the top 1,000
Dasatinib	adverse reactions	none in the top 1,000
Datopotamab deruxtecan	adverse reactions	none in the top 1,000
Decitabine	adverse reactions	none in the top 1,000
Diclofenac and menthol and methyl salicylate	adverse reactions	none in the top 1,000
Elranatamab	adverse reactions	none in the top 1,000
Ensartinib	adverse reactions	none in the top 1,000
Estazolam	adverse reactions	none in the top 1,000
Etravirine	adverse reactions	none in the top 1,000
Etuvetidigene autotemcel	adverse reactions	none in the top 1,000
Floxuridine	adverse reactions	none in the top 1,000
Fluoxetine and olanzapine	adverse reactions	none in the top 1,000
Flurbiprofen	adverse reactions (oral label)	none in the top 1,000
Fluvoxamine	adverse reactions	none in the top 1,000
Ganciclovir	adverse reactions	none in the top 1,000
Glycopyrrolate and neostigmine methylsulfate	adverse reactions	none in the top 1,000
Hyaluronidase and pertuzumab and trastuzumab	adverse reactions	none in the top 1,000
Inavolisib	adverse reactions	none in the top 1,000
Lazertinib	adverse reactions	none in the top 1,000
Levoketoconazole	adverse reactions	none in the top 1,000
Levomilnacipran	adverse reactions	none in the top 1,000
Lidocaine and tetracaine	adverse reactions	none in the top 1,000
Lopinavir and ritonavir	adverse reactions	none in the top 1,000
Lutetium lu 177 vipivotide tetraxetan	adverse reactions	none in the top 1,000
Mexiletine	adverse reactions	none in the top 1,000
Miconazole and petrolatum and zinc oxide	adverse reactions	none in the top 1,000
Midodrine	adverse reactions	none in the top 1,000
Midostaurin	adverse reactions	none in the top 1,000
Mosunetuzumab	adverse reactions	none in the top 1,000
Nefazodone	adverse reactions	none in the top 1,000
Nilutamide	adverse reactions	none in the top 1,000
Nisoldipine	adverse reactions	none in the top 1,000
Nitisinone	adverse reactions	none in the top 1,000
Pasireotide	adverse reactions (subcutaneous label)	none in the top 1,000
Pegvaliase	adverse reactions	none in the top 1,000

Source: FDA drug labels via openFDA, read October 8, 2026; FAERS via openFDA, reports through July 30, 2026

Which of them have the most dry skin reports in FAERS?

Counts follow how widely a medicine is used and watched, and they are not a measure of how risky it is.

Source: FDA Adverse Event Reporting System (FAERS) via openFDA, reports through July 30, 2026; MedDRA preferred term “Dry Skin”

What next?

Side effects across medicines: every reaction on PlainMeds
Report a side effect to the FDA: MedWatch